DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment ocm and tbx16

DIOPT Version :9

Sequence 1:	NP_001188998.1	Gene:	ocm / 37874	FlyBaseID:	FBgn0266083	Length:	2175	Species:	Drosophila melanogaster
Sequence 2:	NP_571133.1	Gene:	tbx16 / 30264	ZFINID:	ZDB-GENE-990615-5	Length:	470	Species:	Danio rerio

Alignment Length:	382	Identity:	71/382 - (18%)
Similarity:	115/382 - (30%)	Gaps:	131/382 - (34%)

- Green bases have known domain annotations that are detailed below.

  Fly    18 YRHIKRKYPVSKDFLHSNWWNVERFIVYALSPRCVIRNY-----------------AWRRRRTRS 65
            :|:..|.:.|..|.|:|..|:|.:...:..:....:..|                 .:|...|.|
Zfish   154 HRYHPRFHIVQADDLYSVRWSVFQTFTFPETSFTAVTAYQNTKITKLKIDHNPFAKGFRDEGTNS 218

  Fly    66 VCIIRRVRILLFDPRLKRMIKRRLQNVRHWSKGLVNYYKKMGRIEEHEETEVYRVAEPLAAEELS 130
                            ||...|.|.:....:       |||.:..||...:   ..:|.:.|.|.
Zfish   219 ----------------KRRANRNLPDPERVA-------KKMSKDSEHGSPQ---DVQPSSCEALD 257

  Fly   131 KQMKQQLELLKTGKRSLSLIEETTAIAEVP--------------PKKPKQFPDITEEARVINDSD 181
            .:        ..|::.|    |..|....|              |:.|.              ..
Zfish   258 DE--------HAGRKEL----EVKAERYSPWGGACDRDSGHALRPESPL--------------GS 296

  Fly   182 DRLDAAPSKQAAERTPTKSPAQVAASEDVPTPATPSKEQSGQTSTCSSAEKTDKVEKVGGGSKFL 246
            |..|...|:|......|..|.:.......|:|:  |....|.:|.|.||.:.....:|      |
Zfish   297 DHRDVYSSEQLVPGQNTYQPYRFHEYGKSPSPS--SSSSVGGSSACGSAGRPSFESRV------L 353

  Fly   247 DMLI-------SKVRVKNFARENNMPAEPSAVTFCTSEDEGSADFVG-FDESVHQ--PGMLLTPL 301
            |:..       ||   .:.|.|.::|..|||         |..::.| .:.::.|  ||||.|..
Zfish   354 DVATVPDTDSSSK---PSSAPEFSLPPHPSA---------GHQEYAGVLNMAITQAKPGMLGTHP 406

  Fly   302 VPNNCKTTEGNSAFVSESLDAY----MREHHINDSDSQDDKDKLLEPMGHDGQVTSH 354
            :.::..|.:....:...:...|    ...||:              |..:..|...|
Zfish   407 LYSHYSTEQSLGQWSGAAASQYPPPPPPHHHL--------------PTEYSSQAVHH 449

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
ocm	NP_001188998.1	DUF4801	771..821	CDD:292677
tbx16	NP_571133.1	TBOX	30..217	CDD:238106	10/62 (16%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C170574523
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG3585
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	2	1.830