Protein Alignment ocm and Tbx3

DIOPT Version :10

• Sequence 1: NP_611894.1
• Gene: ocm / 37874
• FlyBaseID: FBgn0266083
• Length: 2175
• Species: Drosophila melanogaster
• Sequence 2: NP_035665.2
• Gene: Tbx3 / 21386
• MGIID: 98495
• Length: 741
• Species: Mus musculus
• Alignment Length: 640
• Identity: 126/640 - (19%)
• Similarity: 214/640 - (33%)
• Gaps: 186/640 - (29%)

  Fly  1546 SSATG---IRSNIEFRKVN-HNDVDE-----LQIPELHQT---DHRWVVLDIFDDFSHIFVPSFS 1598
            |.|||   :...:.|.|:. .|::.:     |..|..|.|   ::.:....|.:.. |.:.|.|
Mouse   190 SPATGEQWMSKVVTFHKLKLTNNISDKHGFTLAFPSDHATWQGNYSFGTQTILNSM-HKYQPRF- 252

  Fly  1599 DMISLTRIHSVMQVAEERQKVVKLQFFPNAPYDAFVTPSSKKKIYFGPLSLDMPPPVLVLLQSVD 1663
               .:.|.:.::::.   ....:...||...:.| ||.....||  ..|.:|..|.......:.:
Mouse   253 ---HIVRANDILKLP---YSTFRTYLFPETEFIA-VTAYQNDKI--TQLKIDNNPFAKGFRDTGN 308

  Fly  1664 -RKMMLREVYQREHSIPVQRHRRSMAFWVLQINGQVHFEIDTESTAKLAAQQKNAIGTPPGLNV- 1726
             |:...:::..:...:..:||::               |...||:::.||....|..:.|.:::
Mouse   309 GRREKRKQLTLQSMRVFEERHKK---------------ETSDESSSEQAAFNCFAQASSPAVSIV 358

  Fly  1727 ----LK--IPSQL--SVEIEKNQDEVP---PVVVIDSDEEDDDG--------ERQLVIDEQDDEQ 1772
                ||  .||:.  ..|.|..::..|   ....|.:...::.|        ..||.       .
Mouse   359 GTSNLKDLCPSEAESDAEAESKEEHGPEACDAAKISTTTAEEPGRDKGSPATRAQLF-------P 416

  Fly  1773 AETDVKQEVERTGFTIQTLPSSGALQITISDSA----------------------ETSSHPAKDV 1815
            ||....::..|..   :..|.|.....|||.|.                      |..:.||||.
Mouse   417 AEPSRARDTARLD---KASPDSRHSPATISSSTRVPGADERRSPGREGPVATKVDEARAIPAKDA 478

  Fly  1816 ---------NTCHFSGGFMPFIANVPAKFGET----APTTQFLTP---------------QVQVT 1852
                     .|.|.:.|.:|.:...|...|:.    .|.  ||.|               ...:.
Mouse   479 FAPLSVQTDATAHLAQGPLPGLGFAPGLAGQQFFNGHPL--FLHPGQFAMGGAFSSMAAGMGPLL 541

  Fly  1853 TSQSGPETLTSSSSSHLPASKSAYPKINESLQELFSSGVPPGGITITKVDSQEKTLPNETVQVVK 1917
            .:.||..|..|...|...||.:|...:         ||            :...|||....|.|.
Mouse   542 ATVSGASTGVSGLESTAMASAAAAQGL---------SG------------ASAATLPFHLQQHVL 585

  Fly  1918 NKKSIAITGI-----HKQVTKAASSTATVTAARAPVVKPQSTSVSKVAPPIRPGATTQP------ 1971
            ..:.:|::..     :.....||::.|:..||.:.|.:....:::.:.|.:|....:.|
Mouse   586 ASQGLAMSPFGSLFPYPYTYMAAAAAASTAAASSSVHRHPFLNLNSMRPRLRYSPYSIPVPVPDS 650

  Fly  1972 -KTLVRLYPKPALAAGRKSLPANAKTPVATPRQSQPVACDKPPLVSGSTLPALVEPSARKSLPSK 2035
             ..|....|..|.|||  .|...|....|:|..   ||.|     |||.|      ::|    |.
Mouse   651 SSLLATALPSMASAAG--PLDGKAAALAASPAS---VAVD-----SGSEL------NSR----SS 695

  Fly  2036 PLAAGEHLRPRQSLPAKVTANPPAAARPDAASTSAQNLTN-VSKAQLAKEEICYG 2089
            .|::|           .|:.:|...:..:||::..|::.. ||..:...:..|.|
Mouse   696 TLSSG-----------SVSLSPKLCSEKEAATSELQSIQRLVSGLEAKPDRSCSG 739

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
ocm	NP_611894.1	MGA_dom	771..821	CDD:464998
		PRK12323	<1933..>2053	CDD:481241	30/126 (24%)
Tbx3	NP_035665.2	T-box_TBX2_3-like	101..305	CDD:410314	26/125 (21%)
		TBX	323..402	CDD:432659	17/93 (18%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	369..469		17/109 (16%)