DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment ocm and tbx-33

DIOPT Version :9

Sequence 1:	NP_001188998.1	Gene:	ocm / 37874	FlyBaseID:	FBgn0266083	Length:	2175	Species:	Drosophila melanogaster
Sequence 2:	NP_499506.2	Gene:	tbx-33 / 190493	WormBaseID:	WBGene00006552	Length:	420	Species:	Caenorhabditis elegans

Alignment Length:	320	Identity:	54/320 - (16%)
Similarity:	108/320 - (33%)	Gaps:	86/320 - (26%)

- Green bases have known domain annotations that are detailed below.

  Fly   325 REHHINDSDSQDDKDKLLEPMGHDGQVTSHSMPPPMDMPAVPEALQRLRTVAERRQYLQRCKNHK 389
            :::|.|......|.........|..::.:.::..|.|:......|...:.|....:.:....|:|
Worm    56 QQYHQNFQGGYSDPFTYQNQYAHQPKIVTVTLQDPQDLWKELHYLSNEQNVLNNGRKIFPALNYK 120

  Fly   390 MGIINNEANVYRELQRKQRQRKVKIGAMQALQASDSQMPFTRQGWQAASYVATEHSKYYYQVIQV 454
            :..:|.|:|...|:..::         |...|...|...::|:..|:...:|.:..|.:  |.:.
Worm   121 VEHLNPESNYKVEILLRR---------MVPYQIQYSNGSWSRKNVQSKKTIAMKTEKVF--VGEF 174

  Fly   455 DGEMVRLPGAQ---------GNNLKREKSPY--LSRLSRKEQEELKCSEQCLDARIQQELKVIPT 508
            .|:.:...|..         |::.|::.:||  :|...::|.:.....::.....:..|.|.||.
Worm   175 TGQDIMRTGLDLSDVKVFNIGSDNKKKVTPYEEMSDAEKREYDTQYSKKKTSMLEVSNECKYIPV 239

  Fly   509 RVSPPRNPKILNQYPLPAIFRPCPLSKKPLQRPLDDDTAALLLAGGSMAVVSMPNVELDVMPQLG 573
                    .|:|:.                                      :||.||.::.:..
Worm   240 --------LIINEI--------------------------------------LPNQELRLVGEFE 258

  Fly   574 RPLDEIA--KRYLQHILPHHDITREWAEFSVSTLQ--APPATMKDAEEQASQTPAGRRKS 629
            ..:.:.|  ..|..||              |..|:  |.|.:..||:::|.|.....|.|
Worm   259 NEITQFATVSSYKNHI--------------VKALRTAANPTSRGDAKQEAVQVGKQWRSS 304

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
ocm	NP_001188998.1	DUF4801	771..821	CDD:292677
tbx-33	NP_499506.2	TBOX	83..296	CDD:214656	47/283 (17%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG3585
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.900