Protein Alignment Nop60B and dkc1

DIOPT Version :10

• Sequence 1: NP_525120.1
• Gene: Nop60B / 37873
• FlyBaseID: FBgn0259937
• Length: 508
• Species: Drosophila melanogaster
• Sequence 2: NP_001028279.2
• Gene: dkc1 / 613144
• ZFINID: ZDB-GENE-031118-120
• Length: 506
• Species: Danio rerio
• Alignment Length: 514
• Identity: 341/514 - (66%)
• Similarity: 412/514 - (80%)
• Gaps: 20/514 - (3%)

  Fly     1 MADVEVRKEKKKKKIKEEPLDGDDIGTLQKQGNFQIKPSSKIAELDTSQWPLLLKNFDKLNIRSN 65
            |||.|.:||||:|..|   :..:::|.:|:.|:|.|||.||:|.|||||||||||||||||||:.
Zfish     1 MADTESKKEKKRKSKK---ISDEEVGDIQESGDFLIKPESKVASLDTSQWPLLLKNFDKLNIRTA 62

  Fly    66 HYTPLAHGSSPLNRDIKEYMKTGFINLDKPSNPSSHEVVAWIKKILKVEKTGHSGTLDPKVTGCL 130
            |||||.|||:||.|.|.:|:::||||||||:||||||||||||:||:||||||||||||||||||
Zfish    63 HYTPLPHGSNPLKRGIHDYVRSGFINLDKPANPSSHEVVAWIKRILRVEKTGHSGTLDPKVTGCL 127

  Fly   131 IVCIDRATRLVKSQQSAGKEYVAIFKLHGAVESVAKVRQGLEKLRGALFQRPPLISAVKRQLRVR 195
            |||::|||||||||||||||||.|.:||.|:|:..::.:.||.|.||||||||||:|||||||||
Zfish   128 IVCVERATRLVKSQQSAGKEYVGIVRLHNALENEHQLARALECLTGALFQRPPLIAAVKRQLRVR 192

  Fly   196 TVYDSKLLDYDETRNMGVFWVSCEAGSYIRTMCVHLGLVLGVGGQMLELRRVRSGIQSERDGMVT 260
            |:|:|||::||..|.:|:||||||||:||||:||||||:|||||||.||||||||:..|:|.:||
Zfish   193 TIYESKLIEYDPERRLGIFWVSCEAGTYIRTLCVHLGLLLGVGGQMQELRRVRSGVLGEKDNLVT 257

  Fly   261 MHDVLDAMWLYENHKDESMLRRVIKPLEGLLVNHKRIIMKDSSVNAVCYGAKITLPGVLRYEDGI 325
            |||||||.|.::::|||:.|||||.|||.||::||||:||||:|||:||||||.|||||||||||
Zfish   258 MHDVLDAQWQFDHNKDETYLRRVIFPLEKLLISHKRIVMKDSAVNAICYGAKIMLPGVLRYEDGI 322

  Fly   326 EIDQEIVICTTKGEAICLAIALMTTATMASCDHGVVAKIKRVIMERDTYPRKWGLGPKASAKKAL 390
            |::|:||:.||||||||.|:||||||.:::||||||||||||||||||||||||||||||.||.:
Zfish   323 EVNQDIVVITTKGEAICTAVALMTTAVISTCDHGVVAKIKRVIMERDTYPRKWGLGPKASQKKMM 387

  Fly   391 IAAGKLDKFGRPNENTPKEWLTGYVDYNAKKPAAQEVSPTNGSSEPSKRKLSTSSVEETAAAAV- 454
            |..|.|||.|:||.:||.:|..|||||:..|       ...|....:|||...|..|..||||.
Zfish   388 IQKGLLDKHGKPNNSTPSDWKEGYVDYSTTK-------VKKGGEASAKRKRDESGSEGEAAAAAQ 445

  Fly   455 ----SEETPSKDKKKKKKKHK---GDEEAPEA-AEEEAEPVEK-EKKKKKKKDKDRDRD 504
                :||...|:||||||:.|   .:|.|.|| ||||.|..|. :|||||||.|:.:.|
Zfish   446 DTSKTEEESKKEKKKKKKEKKQKLAEEAAAEAPAEEETEVTESAKKKKKKKKAKETEAD 504

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Nop60B	NP_525120.1	CBF5	54..379	CDD:273073	246/324 (76%)
dkc1	NP_001028279.2	Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	1..26		11/27 (41%)
		CBF5	51..376	CDD:273073	246/324 (76%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	391..410		10/18 (56%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	419..506		39/86 (45%)