Protein Alignment CG3328 and Myrf

DIOPT Version :10

• Sequence 1: NP_611893.3
• Gene: CG3328 / 37871
• FlyBaseID: FBgn0034985
• Length: 1423
• Species: Drosophila melanogaster
• Sequence 2: XP_006526990.1
• Gene: Myrf / 225908
• MGIID: 2684944
• Length: 1144
• Species: Mus musculus
• Alignment Length: 1160
• Identity: 386/1160 - (33%)
• Similarity: 527/1160 - (45%)
• Gaps: 269/1160 - (23%)

  Fly    39 GHNG--HLS-AGGGVHSHMESPHTSPMNGLDAHLTNSGRVGST----------PVAAQAQSHVHP 90
            |.:|  ||| .|.|.......|...|..|...:..|:..:|:.          |:.|:.::...|
Mouse    68 GSSGLHHLSPPGSGPSPGRHGPLPPPTYGTPLNCNNNNGMGTAPKPFLGGSGPPIKAEPKAPYAP 132

  Fly    91 -QLPESPPDS-QPAYSP--LGEAHGMAMPLQRELIYPGLAPMQHQANMLQTDLGQYASPPQQQHH 151
             .||:||||| ..||||  :.:.|.:.......|.:.|::............|.....||....|
Mouse   133 GTLPDSPPDSGSEAYSPQQVNDPHLLRTITPETLCHVGVSSRLEHPPPPPAHLPGPPPPPPPPPH 197

  Fly   152 FAAPQADVRIKHESELIINPSNLLGQQQPQQQQMQQQQQQLNEQMFAQH-------------HQQ 203
            :...|.|:.:|.|..  :.|...:|......:....||.|:..|:..||             |.:
Mouse   198 YPVLQRDLYMKAEPP--VPPYAAMGPGLVPPELHHTQQTQVLHQLLQQHGAELPPHPSKKRKHSE 260

  Fly   204 HQDSILQDQMLYYDNGAGAGMYATGSYQNLSTCTLTSALGLGDRVQVIGT-SQLSLNRVSAPSTP 267
            ...:.|..|||       .||..                      |..|| :.|..:...|||.|
Mouse   261 SPPNTLNAQML-------NGMIK----------------------QEPGTVTALPPHPARAPSPP 296

  Fly   268 VHSLSRKRKMSTQLDCPEFPSAPKVDAGLQMSPLRASHHSLATPTPAPSHCSASVSPALSAVNSQ 332
            ..              |:.|.:|    |....||     |:|.....|.|...:.||
Mouse   297 WP--------------PQGPLSP----GTGSLPL-----SIARAQTPPWHPPGAPSP-------- 330

  Fly   333 ADNSLDGQPGGVVTGSGSGSGSGSGSGSEAGDPAGGQCIRFNAFQPENWHKLFDQSLQELSVIYY 397
                      |::..|.|.|||..       || ..|.|::...|...|..|:|.:.:||.::.|
Mouse   331 ----------GLLQDSDSLSGSYL-------DP-NYQSIKWQPHQQNKWATLYDANYKELPMLTY 377

  Fly   398 RVDADKGFNFSVSDDAYVCQKKNHFQVTCHARLQGDAKFVKTPSGFEKIKSFHLHFYGVKFEAPN 462
            ||||||||||||.|||:|||||||||||.:..:.|:.|:||||.|.:.:..|:|..:|||.||.|
Mouse   378 RVDADKGFNFSVGDDAFVCQKKNHFQVTVYIGMLGEPKYVKTPEGLKPLDCFYLKLHGVKLEALN 442

  Fly   463 QTIRVEQSQSDRSKKAFHPVPIDLQKHIVSKITVGRLHFSETTNNNMRKKGRPNPEQRFFQLVVG 527
            |:|.:|||||||||:.|:||.::|....|:|:|||||||||||.|||||||:|||:||:|.|||.
Mouse   443 QSINIEQSQSDRSKRPFNPVTVNLPPEQVTKVTVGRLHFSETTANNMRKKGKPNPDQRYFMLVVA 507

  Fly   528 LHVHTISGNFPVVSHGSEKIIVRASNPGQFESDVDLCWQRGLTPESVFHTGRVGINTDRPDESLV 592
            |..|..:.|:.:.:..||:||||||||||||||.|:.|||...|::|||.||||||||||||:||
Mouse   508 LQAHAQNQNYTLAAQISERIIVRASNPGQFESDSDVLWQRAQLPDTVFHHGRVGINTDRPDEALV 572

  Fly   593 VHGNLKVSGHIVQPSDSRAKQEIGELDTSVQLRNLQKIRIVRYRYMPEFAVHSGLRRESDTREIE 657
            ||||:||.|.::.|||.|||:.:.|:||:.||:.:.::|:|.|||.||||..:|:...:     .
Mouse   573 VHGNVKVMGSLMHPSDLRAKEHVQEVDTTEQLKRISRMRLVHYRYKPEFAASAGIEATA-----P 632

  Fly   658 DTGVIAQEVREVIPDAVQEAGSVVLPNGNVIEKFLLVNKDRILMENIGAVKELCKVTCSLETRIE 722
            :||||||||:|::|:||::.|.||..||..||.||:|||:||.|||:||||||||:|.:|||||:
Mouse   633 ETGVIAQEVKEILPEAVKDTGDVVFANGKTIENFLVVNKERIFMENVGAVKELCKLTDNLETRID 697

  Fly   723 HLERANIGQNSQQLRAKDLLE---------------------PRCILPERAAITSYGSRRDGYEV 766
            .|||.:  ....:||..|.|:                     |....|.:.|..|..:..|  :.
Mouse   698 ELERWS--HKLAKLRRLDSLKSTGSSGAFSHAGSQFSRAGSVPHKKRPPKLANKSSPAVPD--QA 758

  Fly   767 C-SSRSLQIVIFLLIIVMAACLAAVSTLYFVEHNKQQ---QADGFFGAGMFRQEAGPTHLSDEER 827
            | |.|.||..|..|::|||..:.::||||.:....::   .|||
Mouse   759 CISQRFLQGTIIALVVVMAFSVVSMSTLYVLSLRSEEDLVDADG--------------------- 802

  Fly   828 HYFHNLHTLFKNKTHGPWPMRQMYATSTSRPPGSRQAEEEAEDLAAVLTKPQVSSGQQQL----- 887
                                  ..|.|||              ....|.:||...|.:.:
Mouse   803 ----------------------SLAVSTS--------------CLLALLRPQDPGGSEAMCPCRS 831

  Fly   888 SLKHGVITTTAPRFSNKTISSKKGKWPPTQEVLRQAAGQKLHL-----PQPVHVVPAAPAKVPPA 947
            |...|   ||..|.|:.| :...|..|....|.:.|:|..|..     .||..:|..:|....||
Mouse   832 SQSFG---TTQLRQSSMT-TGLPGTQPSLLLVTKSASGPALRALDLCSSQPCPIVCCSPPVSSPA 892

  Fly   948 ---ALNDTVASTEKPP---------QAIPLP-QDFENNSIDIDAQQKQSQLKLDEHIVVVGTIAS 999
               ||..|:..|..|.         |..||| .:....|..|.|    :.:...:|...:..:||
Mouse   893 TDPALGPTLTPTPSPSSNPKHSGPGQMAPLPVTNIRAKSWGISA----NGISYSKHSKSLEPLAS 953

  Fly  1000 -----PASDAYDSNSPSVAAHPIRKFNPGTVYTHVYKTVSPPTANLALTTNKVST---EPAQS-- 1054
                 |...:...||||        ||..:.........||..|....|..::::   :||.|
Mouse   954 PVVPFPGGQSKTKNSPS--------FNLQSRARRGAPQPSPSPAQFTQTQGQLASLLPDPAPSLT 1010

  Fly  1055 ---------PLTHALDVPPPA---------LPVRNSSDNPDALDLQNLSNTNESV 1091
                     |:|....||..|         :||.:|:....:|.||..|:|..||
Mouse  1011 SIQLLENSMPITSQYCVPEGACRLGNFTYHIPVSSSTPLHLSLTLQMNSSTPVSV 1065

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG3328	NP_611893.3	NDT80_PhoG	413..560	CDD:398753	88/146 (60%)
		Peptidase_S74_CIMCD	607..729	CDD:381748	66/121 (55%)
Myrf	XP_006526990.1	NDT80_PhoG	393..540	CDD:398753	88/146 (60%)
		Peptidase_S74_CIMCD	587..705	CDD:381748	66/124 (53%)
		PHA03247	<816..1096	CDD:223021	66/266 (25%)
		MRF_C2	1009..1143	CDD:464020	15/57 (26%)