Protein Alignment Naa35 and MAK10

DIOPT Version :10

• Sequence 1: NP_611891.1
• Gene: Naa35 / 37866
• FlyBaseID: FBgn0034982
• Length: 784
• Species: Drosophila melanogaster
• Sequence 2: NP_010861.3
• Gene: MAK10 / 856657
• SGDID: S000000779
• Length: 733
• Species: Saccharomyces cerevisiae
• Alignment Length: 845
• Identity: 179/845 - (21%)
• Similarity: 310/845 - (36%)
• Gaps: 238/845 - (28%)

  Fly    58 DVQRTMRSGSAAEDITQYPMHGWVDVTKEFHDACAELQPGELAQDMLFGLFEAMSAIEIMDPKM- 121
            :|...:.|.|..:|..|.     ||||..|.:.|::|:|..:.:|..|.|||...::|:.:.|:
Yeast     2 EVDSILGSLSITDDFDQL-----VDVTSLFDELCSKLKPEAIVKDPRFDLFEGTHSLEVNNSKLD 61

  Fly   122 -------------DVGMGFDKQDLPPPSFEAAIATGAIKLDDLTPSELIGIYDALFSCLVSWL-E 172
                         ||.:.:|    ||.:..||||                  |.|..|::||| :
Yeast    62 SSLIELTAEEIEFDVNVAYD----PPLASVAAIA------------------DRLLRCVISWLND 104

  Fly   173 GNSMDQVLFTCLYLHA--PAQIK---------------DKALRVFCTAVRNLIVVIKKIIAVAAV 220
            ..::...:.:|.|..:  .:.:|               ||.|......|..|...::|:::...|
Yeast   105 YQTLPTTVLSCRYTESLLSSLVKGTTAGSSWCTGNILYDKVLGSCILGVCYLTKFVQKLLSAGIV 169

  Fly   221 NEEEDF-----------QLYGNSALL--AAEKAQPATVYSSLKDVEDELIRKCKKLTSTEDWMAV 272
            .||||.           .|.|...::  ..|..|....||     :|.|
Yeast   170 FEEEDLNFNNMGFNTFDNLPGQDVVINSLTESLQILEAYS-----DDSL---------------- 213

  Fly   273 VHRLRFMRHLFQVI---YHVEQMASNDTVDD---KVDIYKILLVASEMLPGIRNTLDRGTQPEKG 331
              .|..::|:.::|   .|:|     |.:.|   |......|:..:..:.||...|.  ..|.||
Yeast   214 --HLTMLKHILKIIICLVHLE-----DHLTDYSTKTSHLDELIENANSVNGIFPQLQ--LSPPKG 269

  Fly   332 SDAPNPMGFSPRI--HDRSQPPAFPRSIKIRDRPSSYQFLEEMISRFKYACKVTKYKDYYSALNF 394
            :       ||..|  |..:|.|  ||  ||...|:.|.....:.:..|....|.|.:.......|
Yeast   270 A-------FSTYIQKHRSNQFP--PR--KITKLPTDYSGFITLANDVKTILLVDKAESALETYQF 323

  Fly   395 FIEYSKKSGQCILSRSVLQTLFSANMRMAHGKLPMKQFLRHSVQVFNSPPVLNAKHPVAADPKVQ 459
            ...::|...:.:::|.:....|..:.|...||....||....|:.|      :|:.|...:..:.
Yeast   324 AKFFNKLEQRHVIARILFPLFFIRDDRTVLGKFSYTQFYLLHVKEF------SAQTPSEFESSIG 382

  Fly   460 QHLENFFRYCINMNTFTQFIRICGFNRARQRDKLARLIENFDTIQVDAARLDSMMNQLANERAME 524
            ..|..     .:.|...::.:.|..|..|.|....|.:..:|::|   |:.:|:.:|:
Yeast   383 NELIQ-----ESSNMLLEWYQNCSQNTCRYRQGFNRQLILWDSLQ---AQFESVNSQV------- 432

  Fly   525 GNEPMATALKHSTHFSTWVLYNCFRAMLIFLMSGFELELYAVHEFLYIYWYPYEFLIGFLVSALT 589
                          :.:|..:....:|:.|.:.||:|::|...|...::||.| :|...|.:.|.
Yeast   433 --------------YCSWTYFMKLSSMIEFSLKGFDLDIYKPFEAYSMFWYVY-YLSHHLETFLK 482

  Fly   590 RTENILLAQEEYAEHQSKTQSGGSGAAKNRKAAKPKKNKKTQRPYR-----------AEIVFYHA 643
            .::|         :.:|...:..|...|.:|....:|..:.:..||           |...|.:.
Yeast   483 DSQN---------DIESNINAIHSMNKKLKKLKAGEKKDQLRLKYRFAMDNEMEQLQATKQFLNY 538

  Fly   644 LL-------SLC------GGMYKAMGALTKDGRVRLPLSKFDNEEIRYNRRFLPFATLTSPPPVS 695
            ||       |||      ..:.|:.|.:  |.:...| |||.||.:.:|.||.||.::..|....
Yeast   539 LLKEINITKSLCLIEVFQFAILKSFGLI--DNKNSTP-SKFSNERLIHNLRFKPFNSIGVPELPE 600

  Fly   696 YAEFKNVREHMM---RHSVEDLYTYAAKHF--DQARNVLESIQNPDQEM------------LDLL 743
            |..|:...:..:   :.:..|:....|.:|  .:.|||:.||....|.:            ..|:
Yeast   601 YEVFQQTLKDFVIEEKGAAFDIKLERATNFIETEVRNVVSSIDEIMQGIKGGDNNGVLVTGTRLV 665

  Fly   744 Q----------------IARTNFVVMNVLARGHQKEVKRQPEFDFSKH--------SYFPIIKLK 784
            |                ::..:.|::|.|    :|.:|.:...::...        :||||..|:
Yeast   666 QELSLEYYCKLKHTSKALSVNSKVIVNTL----KKNIKNKDSHEYKVELVHTTEGWNYFPIQTLR 726

  Fly   785  784
            Yeast   727  726

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Naa35	NP_611891.1	Mak10	96..227	CDD:461179	37/173 (21%)
MAK10	NP_010861.3	Mak10	35..193	CDD:461179	39/179 (22%)