DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment Naa35 and MAK10

DIOPT Version :9

Sequence 1:	NP_611891.1	Gene:	Naa35 / 37866	FlyBaseID:	FBgn0034982	Length:	784	Species:	Drosophila melanogaster
Sequence 2:	NP_178872.2	Gene:	MAK10 / 815566	AraportID:	AT2G11000	Length:	728	Species:	Arabidopsis thaliana

Alignment Length:	771	Identity:	183/771 - (23%)
Similarity:	309/771 - (40%)	Gaps:	155/771 - (20%)

- Green bases have known domain annotations that are detailed below.

  Fly    80 WVDVTKEFHDACAELQPGELAQDMLFGLFEAMSAIEIMDPKMDVGM-----GFDKQDLPPPSFEA 139
            |.||:.....||::||.|||.....|.||.||||:||||||||.||     ..|:      :.|:
plant    33 WADVSPLLSAACSDLQEGELINGDNFNLFAAMSALEIMDPKMDSGMVSTFYSIDE------AIES 91

  Fly   140 AIATGAIKLDD-LTPSELIGIYDALFSCLVSWLEGNSMDQVLFTCLYLHAPAQIKDKA-LRVFCT 202
            ..|...|..|. :....:|.|.|.|.:|..:|..|:|:.|.:|:|:|:..|.:...:| |..:|.
plant    92 GFAPVPISSDSTVNVQSIIDIMDHLLACEATWHMGHSLAQTVFSCIYVLRPERTSSQALLHSYCR 156

  Fly   203 AVRNLIVVIKKIIAVAAVNEEEDF--QLYG---------NSALL--AAE-------KAQPATVYS 247
            .:|.....:..:::.|..|||||.  ..||         ...||  |.|       :|..||...
plant   157 VIRATCRAVVSVVSDARTNEEEDLFTMTYGLPFSGEEDAKGLLLLNAVEETICRQLRACKATRRR 221

  Fly   248 SLKDVEDELIRK--------CKKLTSTEDWMAVVHRLRFMRHLFQVI------------------ 286
            .|:|.|.|.::.        ||.|         :.|:||.:|....:
plant   222 MLEDAELEPLQSNPHLEESFCKSL---------LCRIRFRKHFLHALNCMRRPQGRGLELARKHI 277

  Fly   287 -YHVEQMASNDTVDDKVDIYKILLVASEMLPGIRNTLDRGTQPEKGSDAPNPMGFSPRIHDRSQP 350
             |.:.::   |:|.|..:..::.:..:    |: |.::..|.    :...:|:||.|.::.|...
plant   278 GYCISEL---DSVLDSAEFLRLDIFEN----GV-NEIEESTT----ASGRSPIGFDPTLNKRLSA 330

  Fly   351 PAFPRSIKIRDRPSSYQFLEEMISRFKYACKVTKYKDYYSALNFFIEYSKKSGQCILSRSVLQTL 415
            |..||:||:.....:..:..:::......|..:...|..:.|.|.|:: :||...:::|:.||.|
plant   331 PTPPRAIKLLSWKKAIDYYVKLLHNLDKICAFSLEPDLEAVLEFVIQF-QKSRPDLVARAHLQLL 394

  Fly   416 FSANMRMAHGKLPMKQFLRHSVQVFNSPPVLNAKHPVAADPKVQQHLENFFRYCINMN-TFTQFI 479
            .     :..|||       :....|    :......:|.|.. :.|..:...|.:.:| .....:
plant   395 L-----VQDGKL-------YGRDTF----LTICARSLALDVS-KNHGLHTNEYILQLNQLMVNLL 442

  Fly   480 RICGFNRARQRDKLARLIENFDTIQVDAARLDSMMNQLANERAMEGNEPMATALKH----STHFS 540
            :|...|...||.||.:::.::....|........|.|....|:.:..:.....|.|    .....
plant   443 KILCANTPWQRRKLGKILNDWSVFHVQMGIAVGQMMQQDTSRSSKNGDKSLLILNHIYGGLEEQI 507

  Fly   541 TWVLYNCFRAMLIFLMSGFELELYAVHEFLYIYWYPYEFLIGFLVSALTRTENILLAQEEYAEHQ 605
            .||       .:.|||.||:|:||:..|:..:|||.|  :|.:.::...|...:::...|
plant   508 NWV-------AIRFLMLGFDLDLYSPSEYCMVYWYMY--IILWKLAERARFRVLIVVNTE----- 558

  Fly   606 SKTQSGGSGAAKNRKAAKPKKNKKTQRPYRAE------IVFYHALLSLCGGMYKAMGALTKDGRV 664
                        .|||   |:||:..|....|      ::|......|..|:...:.||..:|..
plant   559 ------------ERKA---KRNKEYSRDMAREDRISLWVLFLKCQTCLAQGLTVMIAALRNEGMS 608

  Fly   665 RLPLSKFDNEEIRYNRRFLPFATLTSPPPVSYAEFKNVREHMMRHSVEDLYTYAAKHFDQARNVL 729
            ......|:.|..::.:.|......:.|...:|..|.....| .|.....:|.|    |..|:.:.
plant   609 LKSQGPFNTENEKFIQHFELLQKASLPEYDAYESFSKSTSH-ARLDYLPMYEY----FHDAQKIA 668

  Fly   730 ESIQ-----NPDQ--EMLDLLQIARTNFVVMNVLARGHQKEVKRQPEFDFSKHSYF 778
            :.|:     :||:  |:..|.::|..|.|.:|:..:....:|    .|:|:.|.||
plant   669 KDIKVGYANDPDKLAEVTGLEKVAERNIVAVNLFCQDRSLKV----SFEFTHHPYF 720

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Naa35	NP_611891.1	Mak10	96..230	CDD:282030	48/142 (34%)
MAK10	NP_178872.2	Mak10	49..189	CDD:282030	50/145 (34%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	1	1.000	83	1.000	Domainoid score	I2901
eggNOG	1	0.900	-	-		E1_KOG2343
Hieranoid	1	1.000	-	-
Homologene	1	1.000	-	-		H5781
Inparanoid	1	1.050	158	1.000	Inparanoid score	I1657
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D1370304at2759
OrthoFinder	1	1.000	-	-		FOG0004758
OrthoInspector	1	1.000	-	-		oto3275
orthoMCL	1	0.900	-	-		OOG6_103368
Panther	1	1.100	-	-	LDO	PTHR21373
Phylome	1	0.910	-	-
SonicParanoid	1	1.000	-	-		X4443
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	1	0.960	-	-
	13	12.830