Protein Alignment Naa35 and mak10

DIOPT Version :9

• Sequence 1: NP_611891.1
• Gene: Naa35 / 37866
• FlyBaseID: FBgn0034982
• Length: 784
• Species: Drosophila melanogaster
• Sequence 2: NP_596720.1
• Gene: mak10 / 2539689
• PomBaseID: SPBC1861.03
• Length: 708
• Species: Schizosaccharomyces pombe
• Alignment Length: 758
• Identity: 154/758 - (20%)
• Similarity: 287/758 - (37%)
• Gaps: 171/758 - (22%)

  Fly    79 GWVDVTKEFHDACAELQPGELAQDMLFGLFEAMSAIEIMDPKMDVGMGFDKQDLPPPSFEAAIAT 143
            |:||.||.:.:|...|:..:|..|..|.|.:::||.|||:||||.|:     |..|
pombe    36 GYVDCTKSYFEATKSLKEEQLVCDPKFTLLDSISAFEIMEPKMDSGI-----DYQP--------- 86

  Fly   144 GAIKLD---DLTPSELIGIYDALFSCLVSWLEGNSMDQVLFTCLYL----HAP-AQIKDK----- 195
              :::|   ||:..|::.:.|.:.|....|..|:.:.:.|....::    .:| :|:.|.
pombe    87 --LRVDFSRDLSYLEILALMDLIVSAEKEWHYGSPLSESLLCSAHVFSICKSPISQVGDSGFSSG 149

  Fly   196 --------ALRVFCTAVRNLIVVIKKIIAVAAVNEEEDFQ--LYGNSAL--LAAEKAQPATVYSS 248
                    .|..|..||.....::.:...:..:.:|||..  .|..|.|  ...||.. ..:.||
pombe   150 SGRNTTDIVLFPFVLAVIKCCDIVHREFLMGNLYDEEDISSFSYHMSFLQNYPIEKLN-YLLQSS 213

  Fly   249 LKDVEDELIRKCKKLTSTEDWMAVVHRLRFMRHLFQVIYHVEQMASNDTVDDKVDIYKILLVASE 313
            ::.:..|:|:...:|....:  .:::|::....:.:|   .|:.....|:|       .|.:...
pombe   214 IEYLASEVIKFSAELRQIIE--GILNRIQLRIGILRV---YERSDIKTTID-------ALHLIKN 266

  Fly   314 MLPGIRNTLDRGTQPEKGSDAPNPMGFSPRIHDRSQPPAFPRSIKIRDRPSSYQ----FLEEM-- 372
            ::|.|:||:.......|.|.......|  |:..:....|..|:|.......|||    |.::|
pombe   267 LVPEIQNTVSVVDSSIKESILKQYWDF--RVQAQLVATAPVRNIPPTGIEHSYQRILYFADDMLL 329

  Fly   373 -ISRFKYACKVTKYKDYYSALNFFIEYSKKSGQCILS-------RSVLQTLFSANMRMAHGKLPM 429
             ::....|..:..|:       |.:::::      |:       ||.||.|.:||..:.....|
pombe   330 ILNSHTLASSLAVYQ-------FCLDFTR------LNRTPEPYVRSSLQALITANNAVNLRDQP- 380

  Fly   430 KQFLRHSVQVFNSPPVLNAKHP------------VAADPKVQQHLENFFRYCINMNTFTQFIRIC 482
            ..::...::.|:..| .|..:|            .|..|.|:..:.:      :.|.....:|||
pombe   381 TSYMLECIREFSGLP-SNFYNPNTRTVIEKNSISSAYGPLVESLIAH------STNIMVDLVRIC 438

  Fly   483 GFNRARQRDKLARLIENFDTIQVDAARLDSMMNQLANERAMEGNEPMATALKHSTHFSTWVLYNC 547
            ..|..|.|..|..|:........:|..||...              :|.:|..:..||:::.:..
pombe   439 SHNPCRFRRNLINLLPEITVAHFEAEALDLKF--------------VAKSLPSNGPFSSFIYHVK 489

  Fly   548 FRAMLIFLMSGFELELYAVHEFLYIYWYPYEFLIGFLVSALTRTENILLAQEEYAEHQSKTQSGG 612
            ..|:...|:|.||.:|:..      |.:|:.|.:               ....::.||:..:..|
pombe   490 LNAIEHILLSSFEQKLHQP------YQWPHFFAV---------------LDHVFSIHQTHLELHG 533

  Fly   613 SGAAKNRKAAKPKKNKKTQRPYRAEIVFYHALLSLCGGMYKAMGALT----KDGRVRLPLSKFDN 673
                         |::.|....:..:.:.|.:|:.....|.....||    :...::.|....|.
pombe   534 -------------KDRNTPPMAKTFVTYLHRILNAIKETYSGYLLLTVLCMRLNIIKTPSFTLDE 585

  Fly   674 --EEIRYNRRFLPFATLTSPPPVSYAEFKNVREHMMRHSVEDLYTYAAKHFDQARNVLESI---- 732
              :|..|...:.|...|..|.|:..:|...:.:::...|.:||...:.:.|..|:|.|.::
pombe   586 KIQESYYMAHYRPLINLRQPKPLLRSEADCIIKNLQNFSTDDLIIKSNEKFTAAKNSLINVIKSG 650

  Fly   733 --QN--------PDQEMLDLLQIARTNFVVMNVLARGHQKEVK 765
              ||        ....:.:||....||.|.:.:|::.|...:|
pombe   651 FEQNEFINPYFLQTNYLKNLLCCCITNLVSLAILSKDHSANLK 693

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Naa35	NP_611891.1	Mak10	96..230	CDD:282030	35/156 (22%)
mak10	NP_596720.1	Mak10	53..205	CDD:282030	38/167 (23%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG2343
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	70	1.000	Inparanoid score	I1930
OMA	1	1.010	-	-		QHG55136
OrthoFinder	1	1.000	-	-		FOG0004758
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	1	0.900	-	-		OOG6_103368
Panther	1	1.100	-	-	LDO	PTHR21373
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R6180
SonicParanoid	1	1.000	-	-		X4443
TreeFam	0	0.000	Not matched by this tool.
	10	9.900