DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG43775 and PRY3

DIOPT Version :9

Sequence 1:	NP_726425.3	Gene:	CG43775 / 37863	FlyBaseID:	FBgn0264297	Length:	272	Species:	Drosophila melanogaster
Sequence 2:	NP_012457.1	Gene:	PRY3 / 853367	SGDID:	S000003614	Length:	881	Species:	Saccharomyces cerevisiae

Alignment Length:	186	Identity:	37/186 - (19%)
Similarity:	61/186 - (32%)	Gaps:	78/186 - (41%)

- Green bases have known domain annotations that are detailed below.

  Fly    68 DTLAVLNTFRDMLAGGELDTAENKTFPSAKRMRALQWDSELAYMARTHAATVSFMHSECRSTLRF 132
            |.|...|.||.:    .:|||            .|.|...||..|:.:|.             ::
Yeast    28 DVLNEHNKFRAL----HVDTA------------PLTWSDTLATYAQNYAD-------------QY 63

  Fly   133 PLAGEVLALSPPVGHRLSL----TELLRMVFAHIFDEYKTVQDPQSFARRFDSKRDY-------S 186
            ..:|.:.....|.|..|:|    |..:...:..|                  ||.:|       |
Yeast    64 DCSGVLTHSDGPYGENLALGYTDTGAVDAWYGEI------------------SKYNYSNPGFSES 110

  Fly   187 VGHFSIIVNDRVSRVGCGFAVGSNCEKDGKVGFC-----HFLTCHFDYTNVNGSYV 237
            .|||:.:|....:.:|||:.            :|     :::.|.:   |..|:|:
Yeast   111 TGHFTQVVWKSTAEIGCGYK------------YCGTTWNNYIVCSY---NPPGNYL 151

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG43775	NP_726425.3	SCP_euk	66..228	CDD:240180	34/175 (19%)
PRY3	NP_012457.1	CAP_PRY1-like	24..152	CDD:349403	37/186 (20%)
PRY3	NP_012457.1	ser_rich_anae_1	<598..>855	CDD:411418
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C157344581
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG2340
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	1.830