DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG43775 and pi15a

DIOPT Version :9

Sequence 1:	NP_726425.3	Gene:	CG43775 / 37863	FlyBaseID:	FBgn0264297	Length:	272	Species:	Drosophila melanogaster
Sequence 2:	NP_001153449.1	Gene:	pi15a / 561978	ZFINID:	ZDB-GENE-040724-135	Length:	260	Species:	Danio rerio

Alignment Length:	240	Identity:	56/240 - (23%)
Similarity:	87/240 - (36%)	Gaps:	80/240 - (33%)

- Green bases have known domain annotations that are detailed below.

  Fly    57 ASIPDTLKVR----KDTLAVLNTFRDMLAGGELDTAENKTFPSAKRMRALQWDSELAYMARTHAA 117
            |:||.|.:.|    .|.||:|: :.:.:.|        |.||.|..|..:.||..||..|...|:
Zfish    53 ANIPKTRRKRYISQNDMLAILD-YHNKVRG--------KVFPPASNMEYMVWDDTLAKTAEQWAS 108

  Fly   118 TVSFMHSECRSTLRFPLAGEVLALSPPVGHRLSLTELLRMVFAHIFDEYKTVQDPQSFARRFDSK 182
            |..:.|.. |:.|||  .|:  .||...|...|:.:|::    ...||.|...        |...
Zfish   109 TCIWEHGP-RNLLRF--LGQ--NLSVRTGRYRSILQLVK----PWHDEVKDYS--------FPYP 156

  Fly   183 RDYS-----------VGHFSIIVNDRVSRVGCGFAVGSNCEKDGKVGFCH-------------FL 223
            ||.:           ..|::.:|....::|||.            :..||             :|
Zfish   157 RDCNPRCPLKCYGPMCTHYTQMVWATSNKVGCA------------INTCHNMNVWGSVWKRATYL 209

  Fly   224 TCHFDYTNVNGSYV----YKTGKATTGCNDWKTIASIKYSNLCEN 264
            .|::   :..|:::    ||.|...:.|..       .|...|.|
Zfish   210 VCNY---SPKGNWIGEAPYKVGVPCSMCPP-------SYGGSCSN 244

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG43775	NP_726425.3	SCP_euk	66..228	CDD:240180	44/189 (23%)
pi15a	NP_001153449.1	SCP_euk	71..214	CDD:240180	41/183 (22%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C170585795
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG2340
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D1528782at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR10334
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X35
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	6	5.850