DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG43775 and crispld1b

DIOPT Version :9

Sequence 1:	NP_726425.3	Gene:	CG43775 / 37863	FlyBaseID:	FBgn0264297	Length:	272	Species:	Drosophila melanogaster
Sequence 2:	XP_009296842.1	Gene:	crispld1b / 393442	ZFINID:	ZDB-GENE-040426-1204	Length:	509	Species:	Danio rerio

Alignment Length:	288	Identity:	55/288 - (19%)
Similarity:	90/288 - (31%)	Gaps:	87/288 - (30%)

- Green bases have known domain annotations that are detailed below.

  Fly     6 LLAGLLLLLLPMVAGYNYCNNRTHVCDLAQRKHFMCR---LGELKPYGGRAKYYASIPDTLKVRK 67
            |.:|.:||:...........|.||:..:.::  :|.:   ..:.|..|.||           :.:
Zfish     9 LFSGFVLLVTVQTVVSMVIPNATHLEAILEK--YMDKDETWWQSKSRGKRA-----------ISQ 60

  Fly    68 DTLAVLNTFRDMLAGGELDTAENKTFPSAKRMRALQWDSELAYMARTHAATVSFMHSECRSTLRF 132
            ..:.::....:.|.|        :.:|.|..|..:.||:||...|...|.|..:.|.......|.
Zfish    61 SDMQLILDLHNKLRG--------QVYPPASNMEYMVWDTELERSAEHWAHTCLWEHGPSHLLTRI 117

  Fly   133 PLAGEVLAL-----SPPVGHRLSLTELLRMVFAHIFDEYKTVQDPQSFARRFDSKRDYS------ 186
               |:.|..     .||..|                     ||      ..:|..||:|
Zfish   118 ---GQNLGAHWGRDRPPTFH---------------------VQ------AWYDEVRDFSYPYPQE 152

  Fly   187 -------------VGHFSIIVNDRVSRVGCGFAVGSNCEKDGKV-GFCHFLTCHFDYT-NVNGSY 236
                         ..|::.:|....:::||...|..|....|.: ....:|.|::... |..|..
Zfish   153 CNPHCPYRCSGPVCTHYTQLVWATSNKIGCAINVCYNMNVWGMIWAKAVYLVCNYSPPGNWWGHA 217

  Fly   237 VYKTGKATTGCNDWKTIASIKYSNLCEN 264
            .||.|...:.|..       .|...|.|
Zfish   218 PYKHGTPCSACPP-------SYGGGCRN 238

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG43775	NP_726425.3	SCP_euk	66..228	CDD:240180	34/186 (18%)
crispld1b	XP_009296842.1	SCP_euk	64..208	CDD:240180	34/181 (19%)
		LCCL	301..385	CDD:128866
		LCCL	404..501	CDD:281766
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C170585732
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG2340
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D1528782at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR10334
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X35
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	6	5.850