DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG43775 and vap-2

DIOPT Version :9

Sequence 1:	NP_726425.3	Gene:	CG43775 / 37863	FlyBaseID:	FBgn0264297	Length:	272	Species:	Drosophila melanogaster
Sequence 2:	NP_001300377.1	Gene:	vap-2 / 181273	WormBaseID:	WBGene00011462	Length:	507	Species:	Caenorhabditis elegans

Alignment Length:	211	Identity:	54/211 - (25%)
Similarity:	85/211 - (40%)	Gaps:	37/211 - (17%)

- Green bases have known domain annotations that are detailed below.

  Fly    66 RKDTLAVLNTFRDMLAGG-ELDTAENKTFPSAKRMRALQWDSELAYMARTHAATVSFMHSECRST 129
            |..||...|.:|..||.| |.:...|.:.|.|.:|..:::|..|...|:..|....|.||   :.
Worm   316 RNFTLEQHNFYRSRLAKGFEWNGETNTSQPKASQMIKMEYDCMLERFAQNWANNCVFAHS---AH 377

  Fly   130 LRFPLAGEVL---ALSPPVGHRLSLTELLRMVFAHIFDEYKTVQDPQSFARRFDSKRDYSVGHFS 191
            ...|..|:.|   :.|.|....|..|.:.:  :....:|:.|..|.......:|.| ..::||::
Worm   378 YERPNQGQNLYMSSFSNPDPRSLIHTAVEK--WWQELEEFGTPIDNVLTPELWDLK-GKAIGHYT 439

  Fly   192 IIVNDRVSRVGCGFAVGSNCEKDGKVGFCHFLTCHFDYT-NVNGSYVYKTGKAT---------TG 246
            .:..||..|:|||.|   ||.|      ..::.||:... |...:.:|:.|...         |.
Worm   440 QMAWDRTYRLGCGIA---NCPK------MSYVVCHYGPAGNRKNNKIYEIGDPCEVDDDCPIGTD 495

  Fly   247 CNDWKTIASIKYSNLC 262
            |.        |.::||
Worm   496 CE--------KTTSLC 503

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG43775	NP_726425.3	SCP_euk	66..228	CDD:240180	46/165 (28%)
vap-2	NP_001300377.1	SCP	104..253	CDD:214553
vap-2	NP_001300377.1	SCP	315..468	CDD:214553	46/166 (28%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG2340
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D1528782at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR10334
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X35
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	5	4.920