DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG43775 and GLIPR1L2

DIOPT Version :9

Sequence 1:	NP_726425.3	Gene:	CG43775 / 37863	FlyBaseID:	FBgn0264297	Length:	272	Species:	Drosophila melanogaster
Sequence 2:	NP_001257325.1	Gene:	GLIPR1L2 / 144321	HGNCID:	28592	Length:	344	Species:	Homo sapiens

Alignment Length:	163	Identity:	30/163 - (18%)
Similarity:	54/163 - (33%)	Gaps:	29/163 - (17%)

- Green bases have known domain annotations that are detailed below.

  Fly    94 PSAKRMRALQWDSELAYMARTHAATVSFMHSECRSTL-----RFPLAGEVLALSPPVGHRLSLTE 153
            |....:|.:.||..|:..||.......|.|:.....:     :|...||.:.:.|.  :..:.:.
Human    70 PRGSNLRFMTWDVALSRTARAWGKKCLFTHNIYLQDVQMVHPKFYGIGENMWVGPE--NEFTASI 132

  Fly   154 LLRMVFA----HIFDEYKTVQDPQSFARRFDSKRDYSVGHFSIIVNDRVSRVGCGFAVGSNCEKD 214
            .:|...|    :.|:......|..::.:               :|.|...:|||..   :.|.|.
Human   133 AIRSWHAEKKMYNFENGSCSGDCSNYIQ---------------LVWDHSYKVGCAV---TPCSKI 179

  Fly   215 GKVGFCHFLTCHFDYTNVNGSYVYKTGKATTGC 247
            |.:.......|::..........|:.|...|.|
Human   180 GHIIHAAIFICNYAPGGTLTRRPYEPGIFCTRC 212

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG43775	NP_726425.3	SCP_euk	66..228	CDD:240180	26/142 (18%)
GLIPR1L2	NP_001257325.1	SCP_GLIPR-1_like	52..195	CDD:240185	26/144 (18%)
GLIPR1L2	NP_001257325.1	Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	292..344
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C165151326
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG2340
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D1528782at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	4	3.750