DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment CG3253 and large2

DIOPT Version :9

Sequence 1:	NP_001246488.1	Gene:	CG3253 / 37861	FlyBaseID:	FBgn0041706	Length:	389	Species:	Drosophila melanogaster
Sequence 2:	NP_001096468.1	Gene:	large2 / 100125087	XenbaseID:	XB-GENE-5871953	Length:	723	Species:	Xenopus tropicalis

Alignment Length:	337	Identity:	81/337 - (24%)
Similarity:	132/337 - (39%)	Gaps:	80/337 - (23%)

- Green bases have known domain annotations that are detailed below.

  Fly    52 VCLATQTSVERLNSLPQVAANWQGKMSVALFAAGPEEFVVLQYFVTYMRLC-FANIRENATFHLL 115
            |.|..|.|::||..|..:..:|.|.||:||:.:..|    .|.|:.|.:.. ....|.|..:|::
Frog   441 VTLVAQLSMDRLQMLELICRHWDGPMSLALYLSDAE----AQQFLRYAQASEVLQSRTNVAYHVV 501

  Fly   116 TPRDFDKLPRVAALPLNMRGKFDCQYPDRTLKALLKFRSLKTLQWRQRNTYPQNHMRNLARKGCQ 180
                                                        :::...||.|.:||:|.|..|
Frog   502 --------------------------------------------YKEGQLYPVNLLRNVALKNSQ 522

  Fly   181 TKYVFLTDIDIVPSTNSVPQLNHFFRTANCT-KSCAYVIPTFE-IDVRATFPRSKNALVRLIRKG 243
            |.||||:|||.:|.......|.......:.| ...|.::|.|| :..|.:||:||..|:.::..|
Frog   523 TPYVFLSDIDFLPMYGLYEYLRKSISQQDLTGPPKALIVPAFETLRYRLSFPKSKAELLSMLDTG 587

  Fly   244 LARPFHEKVFIYNQYATNFSKWLSPNTNETEVSVSHVVTNFEFLYEPFYIAVDNAPAHDERFLGY 308
            ....|...|:......|:::||   .|..|...|.....     :||:.:...:.|.:|:||||:
Frog   588 ALYTFRYHVWEKGHAPTDYAKW---RTATTPYRVEWAPD-----FEPYVVVRRDCPEYDQRFLGF 644

  Fly   309 GFTRNSQVYEMHIAGYQFYVLSPVFTGHWGLQRKQARPAWREQQNNANRRKFDVFKSEIFVRYKN 373
            |:.:.|.:.|:....::..||...|..|.                 .:...||:.|    .|...
Frog   645 GWNKVSHIMELDAQEHELLVLPNAFIIHM-----------------PHAPSFDISK----FRSSE 688

  Fly   374 DPRLLLKAKKNQ 385
            :.||.::|.|.:
Frog   689 NYRLCVQALKEE 700

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG3253	NP_001246488.1	Glyco_transf_49	52..371	CDD:290607	76/321 (24%)
large2	NP_001096468.1	GT8_LARGE_C	107..386	CDD:133053
large2	NP_001096468.1	Glyco_transf_49	440..709	CDD:290607	81/337 (24%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D729091at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	1.010