Protein Alignment CG4049 and zranb3

DIOPT Version :10

• Sequence 1: NP_611885.3
• Gene: CG4049 / 37860
• FlyBaseID: FBgn0034976
• Length: 1669
• Species: Drosophila melanogaster
• Sequence 2: XP_017208927.2
• Gene: zranb3 / 553237
• ZFINID: ZDB-GENE-060712-1
• Length: 1079
• Species: Danio rerio
• Alignment Length: 1364
• Identity: 236/1364 - (17%)
• Similarity: 424/1364 - (31%)
• Gaps: 500/1364 - (36%)

  Fly   360 NVPDENGQVVVNMAHPEGEETLYLAPQ-IAKVIKPHQIGGVRFLYDNIIESTRRYNKSSGFGCIL 423
            :.|:|   |.:|     |::.|.|.|| :.:.:.|.|..||.|..            |....|::
Zfish    12 SAPEE---VSLN-----GKDALQLLPQKLREKLMPFQREGVCFAL------------SRNGRCMI 56

  Fly   424 AHSMGLGKTLQVVSFCDIFLRHTSAKTVLCVMPINTLQNWLSEFNMWIPRYSTDSNVRPRNFDIF 488
            |..||||||:|.:|...||.:..   .:|.|:|.:....|:.|...|||      .:.||  ||.
Zfish    57 ADEMGLGKTIQAISVAYIFKQEW---PLLIVVPSSLKYPWIEELEKWIP------ELDPR--DIN 110

  Fly   489 VLNDQQKTLTARAKVILNWVHDGGVLLIGYELFRLLALKLVKTRKRKGSVIRPDGMDSSSDLMNL 553
            ::..:..|::         :....|.::||.|....|..|:
Zfish   111 LVESKTDTMS---------ISTSKVTILGYGLLTTDARALL------------------------ 142

  Fly   554 VYEALVKPGPDLVICDEGHRIKNSHAGISLALKEI--RTRRRIVLTGYPLQNNLLEYWCMVDFVR 616
              |||.|....:|:.||.|.:|:.:|..|..|..|  ..:|.|:|||.|......|.:..:|.:.
Zfish   143 --EALNKQQFAVVLVDESHYLKSRNAARSKILVPIIQSAKRAILLTGTPALGRPEELFMQIDALY 205

  Fly   617 PNYLGTRTEFCNMFERPIQNGQCVDSTPDDIKLMRYRAHVLHSLLLGFVQRRSHTVLQLTLPQKY 681
            |...||.:::.|.:        |             .||                         |
Zfish   206 PRRFGTWSDYANKY--------C-------------NAH-------------------------Y 224

  Fly   682 EYVILVKMTAFQRKLYDTFMTDVVRTKAFPNPLKAFAVCCKIWNHPDVLYNFLKKCETDLDLEID 746
            .|.       ..|:.:|                      |:..:|.|.|:..|.:.
Zfish   225 RYF-------GARRQWD----------------------CRGASHLDELHKRLSEI--------- 251

  Fly   747 EEVTKGAATPIVEPSADSSLSLASPLEKKINGSGDPINSIETFSKAENQTLFNIPASSDLNAKYL 811
                                                     ...:.:||.|..:|      .|..
Zfish   252 -----------------------------------------MIRRLKNQVLTQLP------PKIR 269

  Fly   812 NKSPSFYDEKPEPLNYGSFGSEGKNNYWMDSSILPKPGCVEVIKQTDTNMSSNFESITGSSEIVD 876
            .:.|  :|                         |||....|.        |::||
Zfish   270 QRIP--FD-------------------------LPKDAAKEA--------SASFE---------- 289

  Fly   877 LDTNEIKTVETTIQAPCSNNQLDNGCNAGKPSEWNAAGSKNSSGVAAAEPFKKLLKSKQRNEEFS 941
                                            :|                 :||:.|:..|:
Zfish   290 --------------------------------QW-----------------EKLMSSESENQ--- 302

  Fly   942 CSWAVDLMK----NYVSGLISNSPKMEIFFCILKESLNLGDRILLFSQSLLTLN-LLEVYLKSSY 1001
               .|::|.    .|....::.:..::.:..::.||..|  :.|:|:..|..|. ..|..:::
Zfish   303 ---FVEVMSLITHMYKQTAVAKAGAVKDYIKMMLESEQL--KFLVFAHHLSMLQACTEAVIEA-- 360

  Fly  1002 VPGSNQLWTKNSSYFRLDGSTSSQERERLVNEFNANSNVKLFLISTRAGSLGINLTGANRVIIFD 1066
                      .:.|.|:|||..|.||.:||:.|..:.:.::.::|.:|...|:..|.|:.|:..:
Zfish   361 ----------KAGYIRIDGSVPSAERIQLVHRFQNDPDTRVAVLSIQAAGQGLTFTAASHVVFAE 415

  Fly  1067 ASWNPCHDTQAVYRIYRYGQTKPCFVYRIVMDRCLEKKIYDRQIKKQ--------GMSDRIVDEC 1123
            ..|||.|..||..|.:|.|||....::.::.....:..::....:|:        |..:.:..|
Zfish   416 LYWNPGHIKQAEDRAHRIGQTATVHIHYLIAKGTFDTVMWAMLNRKETVTGSALNGKKEYLKAE- 479

  Fly  1124 NPEAHLSMKDITNLCQ----------DYDSDEDTV-----------------------EEVNKST 1155
              |......|..|..|          |.:.|:|.|                       |:..|.|
Zfish   480 --EGDQEKWDFLNFAQAWTPNQMLKGDSEDDKDGVFFSHFERDKQHDIRSFFSPSVHKEKKRKRT 542

  Fly  1156 GDLSKPGSPSEE---GSKPGSA--------------NMSPNASN-------KSNNGPTKPLDDQN 1196
            .|.:..|||..:   |::|...              :.||....       ....|...||....
Zfish   543 EDSTSDGSPLPQLPAGAEPTQTPETQSFDLTADQGEDFSPQVKRFRQVSPLSRRGGKKSPLSPLF 607

  Fly  1197 TPKSPNGASHSPIKTEKNDGQEHAVHVDGII--NTILDMHRHCVTK---------EPFMHESLLV 1250
            .|:..:....:|...:|.:.........|::  ..:.|..|: |.|         :|....||..
Zfish   608 APRRLSAGLQAPRHNQKWNCSSCTFSNSGLLLRCEMCDSPRN-VQKALSPPSSLADPSSSSSLTT 671

  Fly  1251 ------DQKDRKLSQAEKRQAHRSYELEKKAAVNQRFTY---------APAKMNYKIVNNDGTVI 1300
                  |.::...:.::.:..|:  ...::|:.|...|:         .|...|....|:||...
Zfish   672 ICISDSDTENEPSTSSKIQTPHK--HPNQQASPNVAETHKDISEEQGSTPKTFNGDSANDDGAYE 734

  Fly  1301 TK----PMNQQIKTNTSSSTGGRSTRWIPAD---VWQRQGMTAQEMTLPLDVVIP---------T 1349
            ..    .:...:|...|.:|          |   :..:.|:......:|||:.:.         .
Zfish   735 ESGDCVSVYDCLKFCASKNT----------DRIYIHDKDGLPLHCNFIPLDIRLQNWEELPPEFN 789

  Fly  1350 NSADKANII--------LKAGQRVMVLKSAKGIYMQLDSGKIIAIRTTAKTEPEKTNKDDVIDIT 1406
            :|.::..::        |.|.::.||.||.:..:     ..|:.:....:::...::....:...
Zfish   790 HSQNRRQVVRFVREWSSLTAMKQRMVRKSGRVFH-----SPILLLEELTQSQRRHSSTSRYLSKH 849

  Fly  1407 DDGDTDTTKPQSPEEDVKDLTADDEPRVVKNKES---NPATTSRP-EMPAKDRKSTENVQHFKSQ 1467
            |...|.....|.....::          :.||:|   ...:||:| :.|.::.:|:..|     |
Zfish   850 DVAQTSIAVAQKEGGALR----------IINKDSVAFKRTSTSKPADPPNREPESSACV-----Q 899

  Fly  1468 TQPNTTLATTTNQHQLPSDLTYSQP------------------------QQSHQQPQQQASQQQP 1508
            |.|:.......:....|..|:..:|                        .|::.:.:...::|..
Zfish   900 TDPSAGFLQAVDSSGTPLCLSCQKPSGEQHGWAGGFCSPTCMEDFQLRSSQAYMRARVLEAEQGM 964

  Fly  1509 AQQPPPPAYKHQNHLPAAGEGYSNANSIQPNVPLPPHPGAPNSSEAPPPADSSYFQPKPFQHTY 1572
            .||....|  ||.:|.......::...:..|..|...|....:.....||:..::|....:..|
Zfish   965 CQQCGLNA--HQLYLQVRDAPLTHRKDMLDNTWLAQLPLKQLNEMIQSPAEGQFWQVDHIKPVY 1026

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG4049	NP_611885.3	DEXHc_ARIP4	391..653	CDD:350827	63/263 (24%)
		HepA	<392..1121	CDD:440319	134/743 (18%)
zranb3	XP_017208927.2	None