Protein Alignment CG4049 and lds

DIOPT Version :10

• Sequence 1: NP_611885.3
• Gene: CG4049 / 37860
• FlyBaseID: FBgn0034976
• Length: 1669
• Species: Drosophila melanogaster
• Sequence 2: NP_524850.2
• Gene: lds / 45894
• FlyBaseID: FBgn0002542
• Length: 1061
• Species: Drosophila melanogaster
• Alignment Length: 1276
• Identity: 264/1276 - (20%)
• Similarity: 427/1276 - (33%)
• Gaps: 433/1276 - (33%)

  Fly     2 DNPEANMEESNPNYDVNQR------LQKPEGWPHVNEFHPSMMYPDDPRRYFHNASTDPQHQPQ- 59
            ||.: |.:||..:.|.:.|      .:||.|.|..:|         |........:..|..:..
  Fly    76 DNSQ-NSQESEDSEDDSVRPSARNTKRKPLGIPSDSE---------DEEDELEQRALSPSTRMSI 130

  Fly    60 --QHPQQQPEQHPEQHPQHPLHSQQQPQQHPQQQPQQH---PQQQTQQPPQLQPQQHPQ------ 113
              ..||...:...|      :....:.|:.|.:.|...   |:..||....:|...|..
  Fly   131 TGVRPQDLSDDDSE------IEYSDEVQEGPTEAPTAEAVVPRYTTQFAGNIQNDLHSTIGAADS 189

  Fly   114 --------------AQIQPPIPVPISTPMEGT-----MEVPVKMPEYCPETSQPVE-PDRVINPL 158
                          :..:.||.:..||..:.|     |..|            |.| |.:.::|.
  Fly   190 EVLDDSSGSDVLILSNKETPIEILSSTDDDATTNKENMSGP------------PFERPSKSLSPR 242

  Fly   159 AEVAKNTVPYGHKRKN-SAGEDQAANKKLSMAAAEEKKNSHLRKNIRDVMNENNLDTTTLAAQRE 222
            :....:.|   ...|| |....||..|:.:..||  .:.|.::...:.|:::...|        |
  Fly   243 SSAGASVV---KTSKNLSQPTIQAVLKQKTSPAA--PRRSRIKSEDQKVVSQVVYD--------E 294

  Fly   223 ESERLARVAGQQKSMREIQKQVVHK------QIF-------RILQLDESEGIESCAVANPVEHHP 274
            |..:||....|.....::.::|.||      ||.       |.|.:|| :.|.:..|...
  Fly   295 EMRKLAEKRVQVSDAEKLFEKVAHKLPDKGSQIMKRIDTLRRELAMDE-QWISALRVQQS----- 353

  Fly   275 PVDFPEEEIASDTFDDSNSSSLSGGSIEDVLHKGASVQPSEVVTIDDSSDDDCILLSEEEEEEDD 339
              :.|...:...|.:...:.|:                                         |.
  Fly   354 --NVPAVRVVKPTLNPPRAPSI-----------------------------------------DT 375

  Fly   340 EDLNESDDATNSGMHVKDIY----NVPDENGQ----------VVVNMAHPEGEETLYLAPQIAKV 390
            .|.:|..:|.|   .:|.:|    .:...|.|          :.|::....|.|.|...|...||
  Fly   376 LDWDELSEAVN---EIKPVYTGAQGMATFNNQKALTLESLKDLHVSLEDLPGPEVLAEDPVGLKV 437

  Fly   391 -IKPHQIGGVRFLYDNIIESTRRYNKSSGFGCILAHSMGLGKTLQVVS---FC------------ 439
             :..||...:.::      |.|  .:....|.|||..|||||||.::|   .|
  Fly   438 SLMNHQKHALAWM------SWR--ERKLPRGGILADDMGLGKTLTMISSVLACKNGQEMSEGKDE 494

  Fly   440 --------DIFLRHTSAKTV----------------LCVMPINTLQNWLSEFNMWIPRYSTDSNV 480
                    |   ::...|:|                |.|.|.:.|:.|.||....:.|
  Fly   495 SSDSDSEDD---KNKKRKSVTGWKSKGRKDTRRGGTLVVCPASLLRQWESEVESKVSR------- 549

  Fly   481 RPRNFDIFVLNDQQKTLTARAKVILNWVHDGGVLLIGYELFRLLALKLVKTRKRKGSVIRPDGMD 545
                        |:.|:.         ||.|                  ..|:.||..:|
  Fly   550 ------------QKLTVC---------VHHG------------------NNRETKGKYLR----- 570

  Fly   546 SSSDLMNLVYEALVKPGPDL----------VICDEGHRIKNSHAGISLALKEIRTRRRIVLTGYP 600
             ..|::...|:.:.:....|          :|.||.|.::|..:..|||:.::|.:.|..|||.|
  Fly   571 -DYDIVVTTYQIVAREHKSLSAVFGVKWRRIILDEAHVVRNHKSQSSLAVCDLRGKYRWALTGTP 634

  Fly   601 LQNNLLEYWCMVDFVRPNYLGTRTEFCNMFE------RPIQN----GQCVDSTPDDIKLMRYRAH 655
            :||..|:.:.::.|:|          |:.|:      :.|.|    ||                :
  Fly   635 IQNKELDVYALLKFLR----------CSPFDDLHTWKKWIDNKSAGGQ----------------N 673

  Fly   656 VLHSLLLGFVQRRSHTVLQL-----TLPQKYEYVILVKMTAFQRKLYDTFMTDVVRTKAFPNPLK 715
            .|:.|:...:.||:...||.     :||.|...:|.:.:...:..:|.|.|| ..||
  Fly   674 RLNLLMKSLMLRRTKAQLQSDGKLNSLPNKELRLIEISLDKEEMNVYQTVMT-YSRT-------- 729

  Fly   716 AFAVCCKIWNHPDVLYNFL-KKCETDLDLEIDEEVTKGAATPIVEPSADSSLSLASPLEKKINGS 779
            .||             .|| ::.|.:.|.....:..|.....|.:|:.    :.....||....:
  Fly   730 LFA-------------QFLHQRAERETDFNYRSDANKPTYNQIKDPNG----AYYKMHEKFARMA 777

  Fly   780 GDPINSIETFSKAENQTLFNIPASSDLNAKYLNKSPSFYDEKPEPLNYGSFGSEGKNNYWMDSSI 844
            |         ||.|.:       |.|:....|..                            ..|
  Fly   778 G---------SKKEVK-------SHDILVLLLRL----------------------------RQI 798

  Fly   845 LPKPGCVEVIKQTDTNMSSNFESITGSSEIVDLDTNEIKTVETTIQAPCSNNQLDNGCNAGKPSE 909
            ...||.::.       |....||.|......|.||.||..:....:...::...|     |:.|.
  Fly   799 CCHPGLIDA-------MLDGEESQTMGDHSSDSDTPEIDLLAQLNKLAITDTSTD-----GQQSV 851

  Fly   910 WNAAGS-----KNSSGVAAAEPFKKLLKSKQRNEEFSCSWAVDLMKNYVSGLISNSPKMEIFFCI 969
            .||...     .:.:.:|.|.  |.|||                ..|.|..|...|.|:.:...|
  Fly   852 ANAGDDGPPLLPDEARIAKAS--KNLLK----------------RSNPVFNLHRPSSKINMVIQI 898

  Fly   970 LKESL--NLGDRILLFSQSLLTLNLLEVYLKSSYVPGSNQLWTKNSSYFRLDGSTSSQERERLVN 1032
            ||.|:  :..|:.::.||....|::|..:|....|           :...|:|:...:.|:.:||
  Fly   899 LKTSILKSSDDKAIVVSQWTSVLDILRDHLSKDGV-----------ATLSLNGTIPVKNRQDIVN 952

  Fly  1033 EFNANSNVK-LFLISTRAGSLGINLTGANRVIIFDASWNPCHDTQAVYRIYRYGQTKPCFVYRIV 1096
            |||..:|.| :.|:|..||.:|:||.|||.:::.|..|||..:.||..||||.||.|...:|:.:
  Fly   953 EFNDRNNQKRVLLLSLTAGGVGLNLIGANHLLLLDLHWNPQLEAQAQDRIYRVGQKKNVIIYKFM 1017

  Fly  1097 MDRCLEKKIYDRQIKKQGMSDRIVDECNPEAHLSMKDITNL 1137
            ....:|::|...|.||..::|.::......:.|::.|:..|
  Fly  1018 CVDTVEQRIKGLQDKKLDLADGVLTGAKVSSKLTIDDLKGL 1058

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG4049	NP_611885.3	DEXHc_ARIP4	391..653	CDD:350827	65/320 (20%)
		HepA	<392..1121	CDD:440319	178/801 (22%)
lds	NP_524850.2	HepA	287..1041	CDD:440319	214/1013 (21%)
		DEXHc_TTF2	439..686	CDD:350830	67/335 (20%)