Protein Alignment CG4049 and dom

DIOPT Version :10

• Sequence 1: NP_611885.3
• Gene: CG4049 / 37860
• FlyBaseID: FBgn0034976
• Length: 1669
• Species: Drosophila melanogaster
• Sequence 2: NP_001286676.1
• Gene: dom / 45655
• FlyBaseID: FBgn0020306
• Length: 3233
• Species: Drosophila melanogaster
• Alignment Length: 1911
• Identity: 379/1911 - (19%)
• Similarity: 648/1911 - (33%)
• Gaps: 570/1911 - (29%)

  Fly   144 ETSQPVEPDRVINPLAEVAKN-------TVPYGHKRKNSAGEDQAANKKLSMAAAEEKKNSHLRK 201
            |.:|.::..||.:.:|...|:       .|.|.|:.|......||.::.||....:.:|.|   :
  Fly   602 EKAQELQLKRVASFIAREVKSFWSNVEKLVEYKHQTKIEEKRKQALDQHLSFIVDQTEKFS---Q 663

  Fly   202 NIRDVMNENNLDTTTL------AAQREESERLARVAGQQKSMREIQKQV-----VHKQIFRILQ- 254
            .:.:.||::..||.:|      :.:||..:.....:|.:.....|.|..     |.:::..:.:
  Fly   664 QLVEGMNKSVADTPSLNSSRLTSPKRESDDDFRPESGSEDDEETIAKAEEDAADVKEEVTALAKE 728

  Fly   255 ----------------LDESEGIESCAVANPVEHHPPVDFPEEEI----ASDTFDDSNSSSL--- 296
                            |:..:.:.....::.::...|.|..:.|.    |||  ||.|:.|.
  Fly   729 SEMDFDDFLNDLPPGYLENRDKLMKEEQSSAIKTETPDDSDDSEFEAKEASD--DDENTISKQEE 791

  Fly   297 -----------------SGGSIEDVLHKGASVQP-----SEVVTID---DSSDDDCILLSEEEEE 336
                             :..|:|.:|.|..|.||     .::...|   ||.||...:.|.||.|
  Fly   792 AEQEIDHKKEIDELEADNDLSVEQLLAKYKSEQPPSPKRRKLAPRDPELDSDDDSTAVDSTEESE 856

  Fly   337 ----EDDEDL------------NESDDATNSGMHVKDIYNVPDENGQVVVNMAHPEGEETLYLAP 385
                ||:|||            :|.:|...|.|...|..:....:|...  .|....::.|..|.
  Fly   857 DAATEDEEDLSTVKTDTDMEEQDEQEDGLKSLMADADATSGAAGSGSTA--GASGNKDDMLNDAA 919

  Fly   386 QIAKVIKP--------HQIGGVRFLYDNIIESTRRY-------------NKSSGFGCILAHSMGL 429
            .:|:.::|        :.:..|.||   :..|.|.|             .|.:|   |||..|||
  Fly   920 ALAESLQPKGNTLSSTNVVTPVPFL---LKHSLREYQHIGLDWLVTMNERKLNG---ILADEMGL 978

  Fly   430 GKTLQVVSFCDIFLRHTS-AK----TVLCVMPINTLQNWLSEFNMWIPRYSTDSNVRPRNFDIFV 489
            |||:|.::    .|.|.: ||    ..|.|:|.:.:.||..||..|.|           .|.|..
  Fly   979 GKTIQTIA----LLAHLACAKGNWGPHLIVVPSSVMLNWEMEFKKWCP-----------GFKILT 1028

  Fly   490 LNDQQKTLTARAKVILNWVHDGG--VLLIGYELFRLLALKLVKTRKRKGSVIRPDGMDSSSDLMN 552
            ....||   .|....:.|.....  |.:..|   :|:.......|::|...:
  Fly  1029 YYGSQK---ERKLKRVGWTKPNAFHVCITSY---KLVVQDQQSFRRKKWKYL------------- 1074

  Fly   553 LVYEALVKPGPDLVICDEGHRIKNSHAGISLALKEIRTRRRIVLTGYPLQNNLLEYWCMVDFVRP 617
                          |.||...|||..:.....|....|.||::|||.||||:|:|.|.::.|:.|
  Fly  1075 --------------ILDEAQNIKNFKSQRWQLLLNFSTERRLLLTGTPLQNDLMELWSLMHFLMP 1125

  Fly   618 NYLGTRTEFCNMFERPIQNGQCVDSTPDDIKLMRYRAHV---LHSLLLGFVQRRSHTVLQLTLPQ 679
            ....:..||...|..|:..  .::..      |.|...:   ||.::..|:.||....::..:|:
  Fly  1126 YVFSSHREFKEWFSNPMTG--MIEGN------MEYNETLITRLHKVIRPFLLRRLKKEVEKQMPK 1182

  Fly   680 KYEYVILVKMTAFQRKLYDTFMT-----DVVRTKAFPNPLKAFAVCCKIWNHPDVL--------- 730
            |||:||..:::..||.||:.||:     :.::|....:.:.......|:.|||::.
  Fly  1183 KYEHVITCRLSNRQRYLYEDFMSRAKTRETLQTGNLLSVINVLMQLRKVCNHPNMFEARPTISPF 1247

  Fly   731 -----------------------------YNFL----------------------KKCETDLD-- 742
                                         .|.|                      :|...|:|
  Fly  1248 QMDGITFHTPRLVCDIMEYDPFTQINLETLNLLLLHLEQTMTAYVSHKSRLLAPPRKLIEDIDTA 1312

  Fly   743 --------------------LEIDEEV----TKGAATPIVEPSADSSLSLASPLE-----KKING 778
                                .|:.:.:    .|..|:|.:.......:.:.:.|.     |:::.
  Fly  1313 PLPAPRCPNGKYRFHIRVRSAELAQRIKLNAVKVGASPAMRLEGSKIMPMRNLLPSGRVLKRVSA 1377

  Fly   779 SGDP---------INSIETFSKAENQTLFNIPASSDL-NAKYLNKSPSFYDEKPEPLNYGSFGSE 833
            |.:|         |||:.|.:.:.........|.|.| |:|.|......  ..|.|........:
  Fly  1378 SINPVNMALKPVVINSVVTTTSSSTTASSPTGALSVLSNSKLLGARSQI--NAPTPAKVAKTMQD 1440

  Fly   834 GKNNYWMDSSI--------LPKPGCVEVIKQTDTNMSSNFESITGSSEIV------DLDTNEIKT 884
            ||..:::..:.        |...........|.|:.::...|.|...:::      ||.|:...|
  Fly  1441 GKPFFYLTPATNSGAAGARLTLTSKTTASASTTTSRTTVTASTTSGQQLIRDPIVKDLATHVKST 1505

  Fly   885 V--------------ETTIQAPCSNNQL-----------------------------DNGCNAG- 905
            |              ||..:.|....:|                             ...|...
  Fly  1506 VQKQSIANGKTEPEEETEAEDPYKVQELIQMRKEQRLAALKRMAMINRRRTDATPIYGEDCREAI 1570

  Fly   906 ----------KPSEWNAAGSKNSSGVAAAE---PFKKLLKS-KQRNEEFSCSWA----------V 946
                      |.|.|...|..|.....|..   ....|||| ::|..:....:|          .
  Fly  1571 QRCMQATRSLKRSTWQTRGYANCCTAMAHRNGWSLNHLLKSFEERCADLKPVFANFVIYVPSVCA 1635

  Fly   947 DLMKNYVSGLISN----------------SPKMEIFFCILKE----------------------- 972
            ..::.||..|.|.                .||:.:...|:.|
  Fly  1636 PRIRRYVQNLSSTHWQHEQRIENIVDQALRPKLALLHPIISEMTTKFPDPRLIQYDCGKLQTMDR 1700

  Fly   973 -----SLNLGDRILLFSQSLLTLNLLEVYLKSSYVPGSNQLWTKNSSYFRLDGSTSSQERERLVN 1032
                 .:| |.|:|:|:|....|::||.:|  :|         ....|.||||||..::|:.|:.
  Fly  1701 LLRQLKVN-GHRVLIFTQMTKMLDVLEAFL--NY---------HGHIYLRLDGSTRVEQRQILME 1753

  Fly  1033 EFNANSNVKLFLISTRAGSLGINLTGANRVIIFDASWNPCHDTQAVYRIYRYGQTKPCFVYRIVM 1097
            .||.:..:..|::|||:|.:|||||||:.||.:|:.|||..|.||..|.:|.|||:...:||:|.
  Fly  1754 RFNGDKRIFCFILSTRSGGVGINLTGADTVIFYDSDWNPTMDAQAQDRCHRIGQTRDVHIYRLVS 1818

  Fly  1098 DRCLEKKIYDRQIKKQGMSDRIVDECNPEA----HLSMKDITNLCQDYDSDEDTVEEVNK----S 1154
            :|.:|..|..:..:|:.:||..::..|...    ..::||:..:.|....:....:..||    :
  Fly  1819 ERTIEVNILKKANQKRMLSDMAIEGGNFTTTYFKSSTIKDLFTMEQSEQDESSQEKSENKDRIVA 1883

  Fly  1155 TGDLSKPGS---PSEEGSKPGSANMSPNASNKSNNGPTKPLD----------DQNTP---KSPNG 1203
            |..||...|   .:|:.|.....:....|.::.:...||...          |:|.|   :.||.
  Fly  1884 TTTLSDTPSTVVETEKQSLRAFEHALAAAEDEQDVQATKTAKAEVAADLAEFDENIPIATEDPNA 1948

  Fly  1204 ASHSPIKTEKNDGQEHAVHVDGIINTILDMHRHCV-----TKEPFMHESLLVDQKDRKLSQAEKR 1263
            .....::..|.|     :.:..::..:..:.|:.:     |...:..|.|...:.:   .:|:||
  Fly  1949 EGGPQVELSKAD-----LEMQNLVKQLSPIERYAMRFVEETGAAWTAEQLRAAEAE---LEAQKR 2005

  Fly  1264 --QAHRSYELEKKAAVNQRFTYAPAKMNYKIVNNDGTVITKPMNQQIKTNTSSSTGGRSTRWIPA 1326
              :|:|...:.|:..:.::.|.|...:.|.         .|..:.|:              ||
  Fly  2006 EWEANRLAAMHKEEELLKQETEAEEMLTYS---------RKDSSNQV--------------WI-- 2045

  Fly  1327 DVWQRQGMTAQEMTLPLDVVIPTNSADKANIILKAGQRVMVLKSAKGIYMQLDSGKIIAIRTTAK 1391
               .|..|....|..|     ||...|..|                .||:......:..:...|:
  Fly  2046 ---SRNTMEQMPMWCP-----PTPPQDNDN----------------DIYIDYSLSFMYELEPIAE 2086

  Fly  1392 TE--PEKTNKDDVIDITD---DGDTDTTKPQSPEEDVKDLTADDEP--------RVVKN------ 1437
            |:  |....|:.....||   ||.....|.:..:..|...:..|.|        |.:|:
  Fly  2087 TDLPPVYVRKEHKRSRTDAGYDGSRRPNKMRREDNYVPPRSLFDRPTPQLARLRRELKSQRFRGS 2151

  Fly  1438 -KESNPATTSRPEMPAKDRKSTENVQHFKSQTQPNTTLATTTNQHQLPSDLTYSQPQQS------ 1495
             |.:.|....:|::|.|.....|.:..: ...:....|....|...||..|....|.|:
  Fly  2152 FKPNMPIPGLKPQLPTKPLTEPEAMAEW-CVFEDMAILHVLVNLQGLPCSLMLLSPGQTPNWDLV 2215

  Fly  1496 HQQPQQQASQQQPAQQPPPPAYKHQNHLPAAGEGYSNANSIQPNVPLPPHPGAPNSSEAPPPADS 1560
            .:.....:...:.|:|   ..::::.|:....||    ..::          :|...:...|...
  Fly  2216 SEMVNFCSKTYRSARQ---CRWRYETHIQPREEG----KVVE----------SPKKQKKLKPTLR 2263

  Fly  1561 SYFQPKPFQHTYPPQYYDYYDNKHKSAPPGSGYHINNYTSYGNLNFAPYHSNLHPPASYIGAPSS 1625
            :.:...|.::....|.| ..||       .:.::....:.:.::..| |.....||.....|||.
  Fly  2264 TEYLKSPLRYLRTTQLY-VSDN-------NASFYKTMRSRFDSIKTA-YLKKAPPPKRQFSAPSL 2319

  Fly  1626 YVNSNVFPRQHWSSVVNSSPASSESM 1651
            ....::...|.:..:....|.|.:::
  Fly  2320 MNPKHMEVLQEFGILNYDQPVSPQNI 2345

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG4049	NP_611885.3	DEXHc_ARIP4	391..653	CDD:350827	70/289 (24%)
		HepA	<392..1121	CDD:440319	212/991 (21%)
dom	NP_001286676.1	HSA	543..614	CDD:214727	4/11 (36%)
		HepA	692..>1235	CDD:440319	137/608 (23%)
		DEXQc_SRCAP	949..1171	CDD:350761	69/280 (25%)
		SF2_C_SNF	1685..1817	CDD:350180	50/143 (35%)
		DISARM_DrmD_b	<1702..>1936	CDD:468472	72/245 (29%)
		HEC1	<1858..>2031	CDD:444066	32/180 (18%)
		SP1-4_N	2486..>2819	CDD:425404