Protein Alignment CG4049 and rad-54.B

DIOPT Version :10

• Sequence 1: NP_611885.3
• Gene: CG4049 / 37860
• FlyBaseID: FBgn0034976
• Length: 1669
• Species: Drosophila melanogaster
• Sequence 2: NP_001255913.1
• Gene: rad-54.B / 190999
• WormBaseID: WBGene00013792
• Length: 833
• Species: Caenorhabditis elegans
• Alignment Length: 873
• Identity: 192/873 - (21%)
• Similarity: 310/873 - (35%)
• Gaps: 365/873 - (41%)

  Fly   386 QIAKVIKPHQIGGVRFLYDNIIESTRRYNKSSGFGCILAHSMGLGKTLQVVSFCDIFLRHTS--- 447
            :.|:.::|||..|::|::|.:...:.:  ...|.|.|||..|||||:||.::.....|:.:.
 Worm   201 RFARHLRPHQKSGIQFIFDRLRRGSGK--NGGGGGAILADDMGLGKSLQTMAATWALLKGSKTAQ 263

  Fly   448 --AKTVLCVMPINTLQNWLSEFNMWIPRYSTDSNVRPRNFDIFVLNDQQKTLTARAKVILNWVHD 510
              |.:.|.::|.:.:.||.:||:.|         .|...|...:........|.::.:.|.
 Worm   264 QLANSCLIIVPSSLVNNWKAEFDKW---------WRLMRFPAVIALTANDITTYQSTIKLM---- 315

  Fly   511 GGVLLIGYELFRLLALKLVKTRKRKGSVIRPDGMDSSSDLMNLVYEALVKPGPDLVICDEGHRIK 575
             ..|:|.|:|.:....||        .:||                      .|:::|||||::|
 Worm   316 -PYLVISYDLAQRHVEKL--------KIIR----------------------FDVMVCDEGHKLK 349

  Fly   576 NSHAGISLALKEIRTRRRIVLTGYPLQNNLLEYWCMVDFVRPNYLGTRTEFCNM-FERPIQNGQC 639
            |....:...|..:...||::|||.|:||:..|::.::|||||:..|:..||..| .:||.|..:.
 Worm   350 NLDGKLRKTLLSLEIPRRLILTGTPMQNDFEEFYSLLDFVRPSVFGSIVEFRKMCSDRPEQLNEL 414

  Fly   640 VDS-----TPDDIKLMRYRAHVLHSLLLGFVQRRSHTVLQLTLPQKYEYVILVKMTAFQRKLYD- 698
            :|.     |..|:.|..                         ||:|:||::....:..|:.::.
 Worm   415 IDECMLRRTAADVDLKH-------------------------LPEKHEYILFCAASPIQKHVHSE 454

  Fly   699 --TFMT-DVVRTKAFPNPLKAFAVCCKIWNHPDVLYNFLKKCETDLDLEIDEEVTKGAATPIVEP 760
              .:|| |.:....|...|.         |||.:|.:.|:           |:..|
 Worm   455 ICDYMTGDALSLIFFARQLA---------NHPKLLLDNLR-----------EKTEK--------- 490

  Fly   761 SADSSLSLASPLEKKINGSGDPINSIETFSKAENQTLFNIPASSDLNAKYLNKSPSFYDEKPEPL 825
                                         |||                           .|..||
 Worm   491 -----------------------------SKA---------------------------HKHSPL 499

  Fly   826 NYGSFGSEGKNNYWMDSSILPKPGCVEVIKQTDTNMSSNFESITGSSEIVDLDTNEIKTVETTIQ 890
            ...           .|.:.:|:.|..|
 Worm   500 LLA-----------FDGAHMPRGGVKE-------------------------------------- 515

  Fly   891 APCSNNQLDNGCNAGKPSEWNAAGSKNSSGVAAAEPFKKLLKSKQRNEEFSCSWAVDLMKNYVSG 955
                                        ||...|                    .||::|
 Worm   516 ----------------------------SGKLTA--------------------LVDMIK----- 527

  Fly   956 LISNSPKMEIFFCILKESLNLGDRILLFSQSLLTLNLLE---VYLKSSYVPGSNQLWTKNSSYFR 1017
                      .|.:|:|.      .::.|..:.||::::   .||              |....|
 Worm   528 ----------CFRLLQEC------TVIVSNYIETLDMIQQLCEYL--------------NFKVLR 562

  Fly  1018 LDGSTSSQERERLVNEFNAN---SNVKLFLISTRAGSLGINLTGANRVIIFDASWNPCHDTQAVY 1079
            |||.|...:|::||..||.:   ||:  ||:||:||.:|:||.||:|:::||:.|||.:|.||:.
 Worm   563 LDGKTQVPDRQKLVRTFNDHRDPSNI--FLLSTKAGGVGLNLIGASRLVLFDSDWNPANDQQAMA 625

  Fly  1080 RIYRYGQTKPCFVYRIVMDRCLEKKIYDRQIKKQGM---------SDRI---VDECNPEAHLSMK 1132
            ||:|.||.:||.:||::....:|:|:..|||||.|:         .|.|   .||       .:|
 Worm   626 RIWRDGQVRPCHIYRLITTGTIEEKMLQRQIKKTGLGCVIDAIEVGDTIATFTDE-------DLK 683

  Fly  1133 DI------------TNLCQ-------------DYDSDEDTV-----EEVNKSTGDLSKPGSPSEE 1167
            ||            .:||:             |.:.|.|.|     |:::|| |.:.|..|..:|
 Worm   684 DIFTFTGSATECNTHDLCECPCDGCGMLENEMDEEDDGDDVVENDAEKIDKS-GKIDKIDSDDDE 747

  Fly  1168 --GSKPGSANMSPNASNKSNNGP--TKP 1191
              ..:...|:::......|...|  |||
 Worm   748 EADDEELEADVTDEVVEDSQEPPEATKP 775

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG4049	NP_611885.3	DEXHc_ARIP4	391..653	CDD:350827	73/272 (27%)
		HepA	<392..1121	CDD:440319	167/761 (22%)
rad-54.B	NP_001255913.1	HepA	<206..661	CDD:440319	164/744 (22%)