Protein Alignment CG4049 and csb-1

DIOPT Version :10

• Sequence 1: NP_611885.3
• Gene: CG4049 / 37860
• FlyBaseID: FBgn0034976
• Length: 1669
• Species: Drosophila melanogaster
• Sequence 2: NP_510607.2
• Gene: csb-1 / 181674
• WormBaseID: WBGene00000803
• Length: 957
• Species: Caenorhabditis elegans
• Alignment Length: 1071
• Identity: 228/1071 - (21%)
• Similarity: 374/1071 - (34%)
• Gaps: 370/1071 - (34%)

  Fly   277 DFPEE---EIASDTFDDSNSSSLSGGSIEDVLHKGASVQPSEVVTIDDSSDDDCILLSEEEEEE- 337
            ||.|:   |:..:.|.::::..|:.........|......||.|..::|.||:...:.|:..::
 Worm    50 DFDEKWEPELDEEDFCENDADVLAEPISSKSRKKSRRSDSSEFVPSEESDDDEEYEVLEKSRKKG 114

  Fly   338 ---------DDEDLNESDDATNSGMHVKDIYNVPD-ENGQVVVNMAHPEG-----EETLYLAPQI 387
                     ..:|..||||  |.......:.:..| :|.:..::...||.     :..:..:.:.
 Worm   115 RKSGSSSRSSSDDFIESDD--NEDYKSAGLLDDNDSKNFKARIDKLKPEATSELVDTRMVTSEEY 177

  Fly   388 AKVIKPHQI-GGV-----RFLYDNIIESTRRYNKSSGFGCILAHSMGLGKTLQVVSFCDIFLRH- 445
            .|..||.:: .||     :|..:.:....::.:..|  |.|||..||||||:|.|    :|||.
 Worm   178 GKSSKPWKVNAGVWNKLHKFQQEGVEWLQKKTDHRS--GGILADEMGLGKTIQSV----VFLRSI 236

  Fly   446 ----------TSAKTVLCVMPINTLQNWLSEFNMWIPR------YSTDSNVRPRNF--DIFVLND 492
                      |...|.|.|..::.:..|:.|.|.|.|:      :|..|..|..::  .||
 Worm   237 QETARTHYKTTGLDTALIVCHVSIIAQWIKELNQWFPKARVFLLHSHCSTGRQEDYVGSIF---- 297

  Fly   493 QQKTLTARAKVILNWVHDGGVLLIGYELFRLLALKLVKTRKRKGSVIRPDGMDSSSDLMNLVYEA 557
              :.|..|.|.    ..||.::|..|.||         |:.:|                     .
 Worm   298 --RKLQRRRKE----YPDGAIILTTYSLF---------TKLKK---------------------P 326

  Fly   558 LVKPGPDLVICDEGHRIKNSHAGISLALKEIRTRRRIVLTGYPLQNNLLEYWCMVDFVRPNYLGT 622
            :||....:||.||||.|:|.:...|:|::::.|.:|.:|||.|.||.|.|:|.:||||.|..|..
 Worm   327 IVKHLWQVVILDEGHYIRNENTKCSIAMRKLMTTQRFILTGTPFQNRLSEFWKLVDFVHPGRLSD 391

  Fly   623 RTEFCNMFERPIQNGQCVDSTPDDIKLMRYRAHV-LH----SLLLGFVQRRSHTVLQLTLPQKYE 682
            ...|...|...|..|..::.:| :.....|...| ||    .|:|..:|.....|||  ||:|.|
 Worm   392 SATFHRNFTHIINAGANLNCSP-EAAAKAYECLVALHIAVKPLILRRLQEDHKEVLQ--LPEKQE 453

  Fly   683 YVILVKMTAFQRKLYDTFMTDVVRTKAFPNPLKAFA-------VCCKIWNHPDVLYNFLKKCETD 740
            .|:..:::..||:||..:.......:.....||||.       :|    |||.:.
 Worm   454 IVLSCELSKRQRRLYMEYGNSHQVNEIIERRLKAFVGINHLTNIC----NHPGIY---------- 504

  Fly   741 LDLEIDEEVTKGAATPIVEPSADSSLSLASPLEKKINGSGDPINSIETFSKAENQTLFNIPASSD 805
                                   .|||.|||
 Worm   505 -----------------------RSLSPASP---------------------------------- 512

  Fly   806 LNAKYLNKSPSFYDEKPEPLNYGSFGSEGKNNYWMDSSILPKPGCVEVIKQTDTNMSSNFESITG 870
                                .:||....||
 Worm   513 --------------------KFGSIKDSGK----------------------------------- 522

  Fly   871 SSEIVDLDTNEIKTVETTIQAPCSNNQLDNGCNAGKPSEWNAAGSKNSSGVAAAEPFKKLLKSKQ 935
                          ||.|.:.      .|         :|                ||
 Worm   523 --------------VEMTFKL------FD---------DW----------------FK------- 535

  Fly   936 RNEEFSCSWAVDLMKNYVSGLISNSPKMEIFFCILKESLNLGDRILLFSQSLLTLNLLEVYLKSS 1000
                                    ||.               :|::||:|....:.::|.:|..
 Worm   536 ------------------------SPT---------------NRVILFTQRRTVITMMEYFLAE- 560

  Fly  1001 YVPGSNQLWTKNSSYFRLDGSTSSQERERLVNEFNANSNVKLFLISTRAGSLGINLTGANRVIIF 1065
                      |......|.|:.|:..|.:::.:|..:.::|:||::||||.||:|||.||:||||
 Worm   561 ----------KGIKCVSLTGADSAAARPKIIKKFEDDVSIKVFLMTTRAGGLGLNLTCANKVIIF 615

  Fly  1066 DASWNPCHDTQAVYRIYRYGQTKPCFVYRIVMDRCLEKKIYDRQIKKQGMSDRIVDECNPEAHLS 1130
            |..|||..|.||..||||.|||....:||:|.:..:|...:.:|::|:.::.|::.....:..:.
 Worm   616 DPDWNPQADNQAKNRIYRMGQTNDVAIYRLVSNGTIEDLKFFKQVQKENLAARLLHNAEIDQFVP 680

  Fly  1131 MKDITNLCQDYDSDEDTVEEVNKSTGDLSKPGSPSEEGSKPGSANMSPNASNKSNNGPTKPL--- 1192
            ...:.:|.:......:..|......|::::.||..::..|...........||......|.|
 Worm   681 NNTLADLFRLKPKGLEGSEIGVYLDGEIAREGSKKQKRDKVEKKAAKKRMKNKLAGFEDKKLLLS 745

  Fly  1193 ---DD------QNTPKSPNGASHSPIKTEK-----NDGQEHAVHVDGIINTILDMHRHCVTKEPF 1243
               ||      :::....|.:|.:.|:..|     :|.....:|.:|         |...|.:..
 Worm   746 LFDDDKLVAMREHSISLQNSSSMNRIEKMKMRKSIDDAVGSLLHTEG---------RLAHTWKQV 801

  Fly  1244 MHESLLVDQKDRKLSQAEKRQAHRSYELEKK 1274
            .|         ::|.:..|:..:..|.:|::
 Worm   802 FH---------KQLRKTLKKSINGDYFVEEE 823

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG4049	NP_611885.3	DEXHc_ARIP4	391..653	CDD:350827	80/286 (28%)
		HepA	<392..1121	CDD:440319	177/765 (23%)
csb-1	NP_510607.2	HepA	<193..670	CDD:440319	173/753 (23%)