Protein Alignment CG4049 and rad-54.L

DIOPT Version :10

• Sequence 1: NP_611885.3
• Gene: CG4049 / 37860
• FlyBaseID: FBgn0034976
• Length: 1669
• Species: Drosophila melanogaster
• Sequence 2: NP_492438.1
• Gene: rad-54.L / 172728
• WormBaseID: WBGene00004298
• Length: 818
• Species: Caenorhabditis elegans
• Alignment Length: 1120
• Identity: 261/1120 - (23%)
• Similarity: 407/1120 - (36%)
• Gaps: 405/1120 - (36%)

  Fly   192 EEKKNSH---------LRKNIRDVMNENNLDTTTLAAQREESERLARVAGQQKSMREIQKQVVHK 247
            |..::||         |.|..|:|..| ||.:|:..|..::.:.|. .:|:.:..:.|.|..:..
 Worm     7 ENLEDSHGKDVNIPVELPKRKREVTPE-NLPSTSSTAPTQKRKSLG-YSGRTEEPKNIHKTFISP 69

  Fly   248 QIFRILQLDESEGIESCAVANP-VEHHPPVDFPE-------------EEIASDTFD--------- 289
              |........:|:.....|.| :|  |||...|             ..:||::.|
 Worm    70 --FSTSVSPSKQGLRRRKKALPAIE--PPVSVEEASPLRFVNIDVFSRRMASESSDHDAMIAKLL 130

  Fly   290 -------------DSNSSSLSGG----SIEDVLHKGASV--QPSEVVTIDDSSDDDCILLSEEEE 335
                         ...|..|.|.    ::.|..|:||.:  .|..              |||..:
 Worm   131 SRKFSIPMEGYMLSGRSLGLGGNRRKCALFDPYHEGALILYAPEH--------------LSEHAQ 181

  Fly   336 EEDDEDLNESDDATNSGMHVKDIYNVPDENGQVVVNMAHPEGEETLYLAPQIAKVIKPHQIGGVR 400
            .::|:|              :.::.|.|                     |.:.|:::|||..||:
 Worm   182 LKEDKD--------------RKVHVVAD---------------------PVVGKILRPHQRDGVK 211

  Fly   401 FLYD-----NIIESTRRYNKSSGFGCILAHSMGLGKTLQVVSFCDIFLRH------TSAKTVLCV 454
            |::|     ||.|.         .|||:|..||||||||.:|.....||.      |.:|::: |
 Worm   212 FMWDCVTGINIPEF---------HGCIMADEMGLGKTLQCISLLWTLLRQSPDACPTVSKSII-V 266

  Fly   455 MPINTLQNWLSEFNMWIPRYSTDSNVRP-----RNFDIFVLNDQQKTLTARAKVILNWVHDGGVL 514
            .|.:.::||..|...|:   .|..|..|     |...|..||........|..:        .||
 Worm   267 CPSSLVKNWDKEIKKWL---GTRLNAMPVDSGKREQIIACLNSFMADSKMRCAI--------PVL 320

  Fly   515 LIGYELFRLLALKLVKTRKRKGSVIRPDGMDSSSDLMNLVYEALVKPGPDLVICDEGHRIKNSHA 579
            :|.||.|||.|                          |:::...|    .:||||||||:|||..
 Worm   321 IISYETFRLYA--------------------------NILHSGDV----GIVICDEGHRLKNSEN 355

  Fly   580 GISLALKEIRTRRRIVLTGYPLQNNLLEYWCMVDFVRPNYLGTRTEFCNMFERPIQNGQCVDSTP 644
            ....||..::..||::::|.|:||:||||:.:|:||.|..|||.:||...||..|..|:..|::.
 Worm   356 LTYQALSGLKCARRVLISGTPIQNDLLEYFSLVNFVNPGLLGTASEFRKKFENAILKGRDADASS 420

  Fly   645 DDIKLMRYRAHVLHSLLLGFVQRRSHTVLQLTLPQKYEYVILVKMTAFQRKLYDTFMTDVVRTKA 709
            :|.|....:...:.||:...:.||:..:|...||.|||::|
 Worm   421 EDQKKGEEKTKEMISLVEKCIIRRTSALLTKYLPVKYEHII------------------------ 461

  Fly   710 FPNPLKAFAVCCKIWNHPDVLYNFLKKCETDLDLEIDEEVTKGAATPIVEPSADSSLSLASPLEK 774
                      |||.....:.|||.|.:||....:   .|..|||..        |:||..:.|:|
 Worm   462 ----------CCKNSTLQETLYNKLIECEKQNRI---VEKDKGATA--------SALSFITHLKK 505

  Fly   775 KINGSGDPINSIETFSKAENQTLFNIPASSDLNAKYLNKSPSFYDEKPEPLNYGSFGSEGKNNYW 839
            ..|   .|....:.|.|.:|              ::.||..|.:   ||..|..||.
 Worm   506 LCN---HPYLVYDEFQKPDN--------------RFRNKCLSIF---PESFNPKSFD-------- 542

  Fly   840 MDSSILPKPGCVEVIKQTDTNMSSNFESITGSSEIVDLDTNEIKTVETTIQAPCSNNQLDNGCNA 904
                                      .|.:|..:::|
 Worm   543 --------------------------PSFSGKMKVLD---------------------------- 553

  Fly   905 GKPSEWNAAGSKNSSGVAAAEPFKKLLKSKQRNEEFSCSWAVDLMKNYVSGLISNSPKMEIFFCI 969
                                  :...:..|..:::|.      |:.||...:   ...||:  |.
 Worm   554 ----------------------YILAVTRKTTDDKFV------LVSNYTQTI---DQFMEL--CK 585

  Fly   970 LKESLNLGDRILLFSQSLLTLNLLEVYLKSSYVPGSNQLWTKNSSYFRLDGSTSSQERERLVNEF 1034
            |                                        :...:.|||||.|.::|.::|:.|
 Worm   586 L----------------------------------------RGYDFVRLDGSMSIKQRSKIVDTF 610

  Fly  1035 N-ANSNVKLFLISTRAGSLGINLTGANRVIIFDASWNPCHDTQAVYRIYRYGQTKPCFVYRIVMD 1098
            | ..|.:..||:|::||..|:||.||||:::||..|||.:|.||:.|::|.||.|.||:||::..
 Worm   611 NDPASTIFCFLLSSKAGGCGLNLIGANRLVMFDPDWNPANDDQAMARVWRDGQKKMCFIYRLLAT 675

  Fly  1099 RCLEKKIYDRQIKKQGMSDRIVDECNPEA-HLSMKDITNLCQ-DYDSDEDT------------VE 1149
            ..:|:|::.||..|:.:|..:||.....| |.|.:.:..|.: :.....||            ||
 Worm   676 GSIEEKMFQRQTHKKALSSCVVDAGEDVARHFSSEQLRELFKLESTVASDTHEKLKCKRCIQGVE 740

  Fly  1150 EVNKST-----GDLSKPGSPSEEGSKPGS---------ANMSPNASNKSNNGPTKPLDDQNTPKS 1200
            .|:..|     .|||......:...|...         .::|.....||:|...|.:.::.....
 Worm   741 SVDPPTNADCASDLSNWFHSQKSARKVADNVLRAVFECGSISFVFHQKSHNVEVKKVQEKVEEVD 805

  Fly  1201 PNGASHSPIKTEKND 1215
            .:   :.|.:.|:||
 Worm   806 ED---YVPSEAEEND 817

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG4049	NP_611885.3	DEXHc_ARIP4	391..653	CDD:350827	91/277 (33%)
		HepA	<392..1121	CDD:440319	191/745 (26%)
rad-54.L	NP_492438.1	HepA	<202..698	CDD:440319	191/746 (26%)
		DEAD-like_helicase_N	202..444	CDD:475120	93/292 (32%)