Protein Alignment CG4049 and Smarcad1

DIOPT Version :10

• Sequence 1: NP_611885.3
• Gene: CG4049 / 37860
• FlyBaseID: FBgn0034976
• Length: 1669
• Species: Drosophila melanogaster
• Sequence 2: NP_031984.1
• Gene: Smarcad1 / 13990
• MGIID: 95453
• Length: 1021
• Species: Mus musculus
• Alignment Length: 1227
• Identity: 264/1227 - (21%)
• Similarity: 432/1227 - (35%)
• Gaps: 370/1227 - (30%)

  Fly     2 DNPEANMEESN-PNYDVNQRLQK---PEGWPHVNEFHPSMM----------YPD---DPRRYFHN 49
            :|.|.....:| |:.||.::.:.   ||  |..||...|:.          |.|   |......|
Mouse    43 ENAEGEGSRANTPDSDVTEKTEDSSVPE--PPDNERKASLSCFQNQRAIQEYIDLSSDTEDVSPN 105

  Fly    50 ASTDPQHQPQQHPQ----QQPEQHPEQHPQHPL---HSQQQPQQHPQQQPQQHPQQQTQQPPQLQ 107
            .|:..|.:......    .:|.:..|.|....:   :...:.:...:.:..:..:.||.:  :|.
Mouse   106 CSSTVQEKKFSKDTVIIVSEPSEDEESHDLPSVTRRNDSSELEDLSELEDLKDAKLQTLK--ELF 168

  Fly   108 PQQHPQAQIQPPIPVPISTPMEGTMEVPVKM-------PEYCPETSQPVEPDRVINPLAEVAKNT 165
            ||:.....::   .:..::.|:|.:...:.|       |.....:|...|.|  :|....|.:..
Mouse   169 PQRSDSDLLK---LIESTSTMDGAIAAALLMFGDAGGGPRKRKLSSSSEEDD--VNDDQSVKQPR 228

  Fly   166 VPYGHKRKNSAGEDQAANKKLSMAAAEEKKNSHL-RKNIRDVMNENNLDTTTLAAQREESERLAR 229
            ...|.:...||.......|:.|:....:|:..:. ::.:|:|:.|:....|      |..|.|..
Mouse   229 GDRGEESNESAEASSNWEKQESIVLKLQKEFPNFDKQELREVLKEHEWMYT------EALESLKV 287

  Fly   230 VAGQQKSMREIQKQVVH-KQIFRILQLDESEGIESCAVANPVEHHPPVDF----------PEEEI 283
            .|..|......|.:|.: |::.|  ..:.|:......:...:...|...|          |::.:
Mouse   288 FAEDQDVQCASQSEVTNGKEVAR--NQNYSKNATKIKMKQKISVKPQNGFNKKRKKNVFNPKKAV 350

  Fly   284 ASDTFDDSN--SSSLSG--GSIEDVLHKG-----------ASVQPSEVVTIDDSSDDDCILLSEE 333
            ....:|..:  .|||..  .|.|:|:..|           :|:  :|:..|...|......::|.
Mouse   351 EDSEYDSGSDAGSSLDEDYSSCEEVMEDGYKGKILHFLQVSSI--AELTLIPKCSQKKAQKITEL 413

  Fly   334 EEEEDDEDLNESDDATNSGMHVKDIYNVPD--ENGQVVVNMAHPEGEETLYLAPQIAKV------ 390
            ....:.|.|.......| |:....|:|...  :...||:.:.:...:.:..|..|:..:
Mouse   414 RPFNNWEALFTKMSKIN-GLSEDLIWNCKTVIQERDVVIRLMNKCEDISNKLTKQVTMLTGNGGG 477

  Fly   391 --------------IKPHQIGGVRFLYDNIIESTRRYNKSSGFGCILAHSMGLGKTLQVVSFCDI 441
                          :||:|..|:.:|         ......|...|||..||||||:|.::|...
Mouse   478 WNREQPSLLNQSLSLKPYQKVGLNWL---------ALVHKHGLNGILADEMGLGKTIQAIAFLAY 533

  Fly   442 FLRHTSAKTVLCVMPINTLQNWLSEFNMWIPR------YSTDSNVRPRNFDIFVLNDQQKTLTAR 500
            ..:..:....|.|:|.:|:.|||.|.|:|.|.      |.:....:...|:|.
Mouse   534 LFQEGNKGPHLIVVPASTIDNWLREVNLWCPSLNVLCYYGSQEERKQIRFNIH------------ 586

  Fly   501 AKVILNWVHDGGVLLIGY----------ELFRLLALKLVKTRKRKGSVIRPDGMDSSSDLMNLVY 555
                 |...|..|::..|          .|||.|.|
Mouse   587 -----NKYEDYNVIVTTYNCAISSSDDRSLFRRLKL----------------------------- 617

  Fly   556 EALVKPGPDLVICDEGHRIKNSHAGISLALKEIRTRRRIVLTGYPLQNNLLEYWCMVDFVRPNYL 620
                    :..|.||||.:||..:.....|..|..|.|::|||.|:||||||...:::||.|:..
Mouse   618 --------NYAIFDEGHMLKNMGSIRYQHLMTINARNRLLLTGTPVQNNLLELMSLLNFVMPHMF 674

  Fly   621 GTRT-EFCNMFERPIQNGQCVDSTPDDIKLMRYRAHVLHS--LLLGFVQRR-SHTVLQLTLPQKY 681
            .:.| |...||..        .:.|.|.:.:..:..:.|:  ::..|:.|| ...||:| ||.|.
Mouse   675 SSSTSEIRRMFSS--------KTKPADEQSIYEKERIAHAKQIIKPFILRRVKEEVLKL-LPPKK 730

  Fly   682 EYVILVKMTAFQRKLYDTFMTDVVRTKAFPNPLKAFAVCCKIWNHPDVLYNFLKKCETDLDLEID 746
            :.:.|..|:..|.:||..                              |:|.|||
Mouse   731 DRIELCAMSEKQEQLYSG------------------------------LFNRLKK---------- 755

  Fly   747 EEVTKGAATPIVEPSADSSLSLASPLEKKINGSGDPINSIETFSKAENQTLFNIPASSDLNAKYL 811
                                               .||::|     :|..:.|:.......|.:.
Mouse   756 -----------------------------------SINNLE-----KNTEMCNVMMQLRKMANHP 780

  Fly   812 NKSPSFYDEKPEPLNYGSFGSEGKNNYWMDSSILPKPGCVEVIKQTDTNMSSNFESITGSSEIVD 876
            .....:|  .||.|..            |...:|.:|          |:..:|.:.|....|::
Mouse   781 LLHRQYY--TPEKLKE------------MSQLMLKEP----------THCEANPDLIFEDMEVM- 820

  Fly   877 LDTNEIKTVETTIQAPCSNNQLDNGCNAGKPSEWNAAGSKNSSGVAAAEPFKKLLKSKQRNEEFS 941
                    .:..:...|...|..|
Mouse   821 --------TDFELHVLCKQYQHIN----------------------------------------- 836

  Fly   942 CSWAVDLMKNYVSGLISNSPKMEIFFCILKESLNLGDRILLFSQSLLTLNLLEVYLKSSYVPGSN 1006
             |:.:|:      .||.:|.|.....|||.|....|||::||||..:.|::|||.||.
Mouse   837 -SYQLDM------DLILDSGKFRALGCILSELKQKGDRVVLFSQFTMMLDILEVLLKH------- 887

  Fly  1007 QLWTKNSSYFRLDGSTSSQERERLVNEFNANSNVKLFLISTRAGSLGINLTGANRVIIFDASWNP 1071
                ....|.||||.|...||..|::|||.:.::.:||:||:||.||||||.||.||:.|...||
Mouse   888 ----HQHRYLRLDGKTQISERIHLIDEFNTDMDIFVFLLSTKAGGLGINLTSANVVILHDIDCNP 948

  Fly  1072 CHDTQAVYRIYRYGQTKPCFVYRIVMDRCLEK---KIYDRQIK-KQGMSDRIVDECN 1124
            .:|.||..|.:|.||||...|.:::....:|:   ||..:::| :|.|:  .|||.:
Mouse   949 YNDKQAEDRCHRVGQTKEVLVIKLISQGTIEESMLKINQQKLKLEQDMT--TVDEAD 1003

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG4049	NP_611885.3	DEXHc_ARIP4	391..653	CDD:350827	70/278 (25%)
		HepA	<392..1121	CDD:440319	180/752 (24%)
Smarcad1	NP_031984.1	Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	1..82		12/40 (30%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	124..151		3/26 (12%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	201..246		9/46 (20%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	329..366		6/36 (17%)
		HepA	<480..992	CDD:440319	177/755 (23%)
		DEGH box	623..626		2/2 (100%)
		Nuclear localization signal. /evidence=ECO:0000255	716..733		8/17 (47%)
		DEAD box	1000..1003		2/2 (100%)