DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment enok and SAS2

DIOPT Version :9

Sequence 1:	NP_001286823.1	Gene:	enok / 37859	FlyBaseID:	FBgn0034975	Length:	2291	Species:	Drosophila melanogaster
Sequence 2:	NP_013846.1	Gene:	SAS2 / 855157	SGDID:	S000004734	Length:	338	Species:	Saccharomyces cerevisiae

Alignment Length:	272	Identity:	89/272 - (32%)
Similarity:	143/272 - (52%)	Gaps:	27/272 - (9%)

- Green bases have known domain annotations that are detailed below.

  Fly   695 IEKVNDVSLKSGQNTQSPKSIQIG-KWDIETWYSSP--FPQEYAR-------------------L 737
            |:|.....|....|.::.:.||.| .....|||.|.  |..|..|                   |
Yeast    33 IKKTQKEMLYGILNERNIRQIQFGLNKKFSTWYGSAVYFDPETKRLGCSETKGQLSSVSNSQYWL 97

  Fly   738 LKLFLCEFCLKYTKSRSVLDRHQNKCIWK-QPPGTEIFRQGNISVFEVDGNVNKIYCQNLCLLAK 801
            ..||:||:|.|||..::....|...|.:: :.||...::....::..|.|:..:::||.|||..|
Yeast    98 DTLFVCEYCFKYTDDQTRFVGHVASCPFQYRVPGKIKYKSPEYTIRRVKGSKYQLFCQCLCLFTK 162

  Fly   802 FFLDHKTLYYDVEPFLFYILTKNDQSGCHLVGYFSKEKHCTQKYNVSCILTMPQYQRQGYGRFLI 866
            .:||:|::|:.|:.:.|||:.:...:  ..:|:|||:....|:.|::|||..|.|||:|.|..||
Yeast   163 LYLDNKSMYFKVDHYEFYIVYETGST--KPMGFFSKDLVSYQQNNLACILIFPPYQRRGLGLLLI 225

  Fly   867 DFSYLLSREEGQLGTPEKPLSDLGRLSYFSYWKSVVLEYLYKH--RNYTKITFKDIAIKTGLAIS 929
            :|||.||:.||.:..||.|||..|.:.|..||..::..:|.:.  .:|.|:|.:|::|.||:.::
Yeast   226 EFSYKLSQLEGVISGPEVPLSPFGLIGYLKYWSQILCWHLIEGDLAHYDKVTLEDLSIVTGMRVN 290

  Fly   930 DIALAFELLNFI 941
            |:.|..:.||.|
Yeast   291 DVILTLKHLNCI 302

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
enok	NP_001286823.1	H15	95..152	CDD:294056
		PHD_SF	183..>215	CDD:304600
		PHD	248..292	CDD:214584
		NAT_SF	713..989	CDD:302625	85/254 (33%)
		MOZ_SAS	768..947	CDD:280097	64/176 (36%)
		Ehrlichia_rpt	<1150..>1539	CDD:118064
SAS2	NP_013846.1	SAS2	<31..338	CDD:227360	89/272 (33%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG5027
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	1.810