DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment enok and CG1894

DIOPT Version :9

Sequence 1:	NP_001286823.1	Gene:	enok / 37859	FlyBaseID:	FBgn0034975	Length:	2291	Species:	Drosophila melanogaster
Sequence 2:	NP_651620.1	Gene:	CG1894 / 43378	FlyBaseID:	FBgn0039585	Length:	421	Species:	Drosophila melanogaster

Alignment Length:	394	Identity:	131/394 - (33%)
Similarity:	199/394 - (50%)	Gaps:	41/394 - (10%)

- Green bases have known domain annotations that are detailed below.

  Fly   600 EAGKSYEKCEDDIPYLTEETVMKVQLLEEIERSRET-HSQADGKREMN------NDEDAPGESTK 657
            |.|||..:.:..:....:||........|.:|...| ..|.:|.:|.|      .:..:..:..:
  Fly    55 EMGKSQLQNDSSLQKNIQETKTITGSCIEAQRIGATPKKQLEGVKEPNMISLLHTNASSNVDDRQ 119

  Fly   658 RANPFENQPLPPGVTATDVELYQEVLHKAVVQMSNNHIEKVNDVSLKSGQNTQSPKSIQIGKWDI 722
            |....:|:       .:||:..:|   .|.|::..| ||||                 |.|:::|
  Fly   120 RQETIDNE-------KSDVQKEKE---DAKVKVIRN-IEKV-----------------QFGRYEI 156

  Fly   723 ETWYSSPFPQEYARLLKLFLCEFCLKYTKSRSVLDRHQNKCIWKQPPGTEIFRQGNISVFEVDGN 787
            ||..|||:|....:...:::|||||||...|.....|...|..:.|||:.::|:.||.::||||:
  Fly   157 ETTSSSPYPVINDKATTIYVCEFCLKYMCLRKSYSYHLYDCKKRCPPGSLLYRKDNIYIYEVDGH 221

  Fly   788 VNKIYCQNLCLLAKFFLDHKTLYYDVEPFLFYILTKNDQSGCHLVGYFSKEKHCTQKYNVSCILT 852
            ..::|||.|||::|.||::|.:.|....||||||...|:.|.|..|||::|| .....|::|||.
  Fly   222 KEQLYCQCLCLMSKLFLENKKILYSSSSFLFYILCLKDKDGEHFAGYFAREK-TMLNINLNCILV 285

  Fly   853 MPQYQRQGYGRFLIDFSYLLSREEGQLGTPEKPLSDLGRLSYFSYWKSVVLEYLYKHRNYTKITF 917
            :|.|.|:|||:.|||.||.:||.|..:|.|:||||.:.||.|.|||..::|..|..|.:...:|.
  Fly   286 LPPYMRKGYGKLLIDLSYEISRREACIGGPKKPLSKVARLCYLSYWGHILLNLLRHHSSPDLVTI 350

  Fly   918 KDIAIKTGLAISDIALAFELLNFIKLRKNDGDIRYQINVKIEWKKVLAHHNKMANSKTRIIIEPD 982
            ::::..||....||....|.:...|..|.|..:.|..:..||.::.||..     .|.|:.|..:
  Fly   351 EELSKATGFREEDIISTLEFMGMTKYYKVDHIMFYTTSSIIEDRRGLAQF-----KKPRLTIHRN 410

  Fly   983 CLRW 986
            .|.|
  Fly   411 RLSW 414

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
enok	NP_001286823.1	H15	95..152	CDD:294056
		PHD_SF	183..>215	CDD:304600
		PHD	248..292	CDD:214584
		NAT_SF	713..989	CDD:302625	106/274 (39%)
		MOZ_SAS	768..947	CDD:280097	76/178 (43%)
		Ehrlichia_rpt	<1150..>1539	CDD:118064
CG1894	NP_651620.1	NAT_SF	130..395	CDD:302625	109/286 (38%)
CG1894	NP_651620.1	MOZ_SAS	202..378	CDD:280097	75/176 (43%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C45463874
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG5027
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D629545at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	P	PTHR10615
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	5	4.850