DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment enok and tth

DIOPT Version :9

Sequence 1:	NP_001286823.1	Gene:	enok / 37859	FlyBaseID:	FBgn0034975	Length:	2291	Species:	Drosophila melanogaster
Sequence 2:	NP_001285216.1	Gene:	tth / 32318	FlyBaseID:	FBgn0030502	Length:	428	Species:	Drosophila melanogaster

Alignment Length:	358	Identity:	62/358 - (17%)
Similarity:	113/358 - (31%)	Gaps:	124/358 - (34%)

- Green bases have known domain annotations that are detailed below.

  Fly   287 YRCKTCSKQGFDTPKL-----VKKDNSRIKMEAERMTPSY-----------KYASNKRQSIKK-- 333
            :..:.||::....|.|     |.:::|::.::..:..|.:           ::..::||.:.|
  Fly    37 FNTRLCSERRHRLPFLDPQTGVAQNHSQLFLDKRQRMPGFRQGQIYTYPAARWRKSRRQYLSKMY 101

  Fly   334 ---------------------------------------DGNIESPSTSKLCVYNDGNGQRRKVP 359
                                                   ..::.|.|:..|.:...|..    .|
  Fly   102 SRFPERPFQALRKEHEALVASGVNLGLSSLTSGVGSMPGSNSLASSSSLTLNMLTGGGA----AP 162

  Fly   360 ASLSSRKMNHSEDQFEFPSKQKRSQILQGGYLASQETRKRTFSDLSSTSSSSESEDEDDEDDDRN 424
            |.|.|.   ||:...:|           .|..:.:|         ||:..::..:..|.:|..:.
  Fly   163 AVLGSL---HSDTAHDF-----------NGAFSLEE---------SSSLGAAGGDTSDSKDSQQQ 204

  Fly   425 RNGDDNDQDESTSSDSCTS-------SSSDSDSSESSSDTSEWDDEYDEEEDYDTDRSTIREKNV 482
            ::.....|.::...:....       ..:|.||.|...  |..|||||.:..|...:   |.|.
  Fly   205 QHQQHQHQQQAVKEELLPKEWFYDDMDMNDVDSLEEPK--SPADDEYDYDPRYGNKK---RRKR- 263

  Fly   483 FESGKQSCAKLSTGDGLGSPQNNELGSENWGFAAVAKNPIDIFVKSKHNSNVKGIGYSKPAASTF 547
             ..||:.......|.|.|:.     |..|.|.::.::.                  .|..|.|..
  Fly   264 -RPGKRGGDSGGGGGGGGAG-----GGGNSGGSSSSRR------------------RSAAARSRI 304

  Fly   548 ATSPAA-NRVQKSTPVASSTPEKNSAPI--GGM 577
            .|:.|| :...::.....|.|..|..||  ||:
  Fly   305 TTTDAALDASLEAIESGESVPGSNGGPISSGGI 337

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
enok	NP_001286823.1	H15	95..152	CDD:294056
		PHD_SF	183..>215	CDD:304600
		PHD	248..292	CDD:214584	0/4 (0%)
		NAT_SF	713..989	CDD:302625
		MOZ_SAS	768..947	CDD:280097
		Ehrlichia_rpt	<1150..>1539	CDD:118064
tth	NP_001285216.1	Requiem_N	24..94	CDD:290758	7/56 (13%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C45463868
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	1	0.930