DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment enok and mst1

DIOPT Version :9

Sequence 1:	NP_001286823.1	Gene:	enok / 37859	FlyBaseID:	FBgn0034975	Length:	2291	Species:	Drosophila melanogaster
Sequence 2:	NP_594630.1	Gene:	mst1 / 2543506	PomBaseID:	SPAC637.12c	Length:	463	Species:	Schizosaccharomyces pombe

Alignment Length:	446	Identity:	156/446 - (34%)
Similarity:	221/446 - (49%)	Gaps:	75/446 - (16%)

- Green bases have known domain annotations that are detailed below.

  Fly   554 NRVQKSTPVASSTPEKNSAPIG-GMTIKRQTANGQKKKI-VPLKSMPLEAGKSYEKCEDDIPYLT 616
            :.:..|..:....|||.....| |.:.||..|..:::.| .|.|:.|  :..|.||.|...|
pombe    70 DNIDLSKGIEYPPPEKPKKAHGKGKSSKRPKAVDRRRSITAPSKTEP--STPSTEKPEPSTP--- 129

  Fly   617 EETVMKVQLLEEIERSRETHSQADGKREMNNDEDAPGESTKRANPFENQPLPPGVTATDVELYQE 681
                                               .|||...:|. .|:.||         |.:|
pombe   130 -----------------------------------SGESDHGSNA-GNESLP---------LLEE 149

  Fly   682 VLHKAVVQMSNNHIEKVNDVSLKSGQNTQSPKSIQ---------IGKWDIETWYSSPFPQEYARL 737
            . ||.........:|::.    .||...|:|..|.         ||..:||.||.||:|:|::.:
pombe   150 D-HKPESLSKEQEVERLR----FSGSMVQNPHEIARIRNINKICIGDHEIEPWYFSPYPKEFSEV 209

  Fly   738 LKLFLCEFCLKYTKSRSVLDRHQNKCIWKQPPGTEIFRQGNISVFEVDGNVNKIYCQNLCLLAKF 802
            ..:::|.||..|..|.....||:.||..:.|||.||:|...||.||:||...:.:|:|:|||:|.
pombe   210 DIVYICSFCFCYYGSERQFQRHREKCTLQHPPGNEIYRDDYISFFEIDGRKQRTWCRNICLLSKL 274

  Fly   803 FLDHKTLYYDVEPFLFYILTKNDQSGCHLVGYFSKEKHCTQKYNVSCILTMPQYQRQGYGRFLID 867
            |||||.|||||:|||||.:.:.|:.||||||||||||..::.||::||||:|||||.|||:.||.
pombe   275 FLDHKMLYYDVDPFLFYCMCRRDEYGCHLVGYFSKEKESSENYNLACILTLPQYQRHGYGKLLIQ 339

  Fly   868 FSYLLSREEGQLGTPEKPLSDLGRLSYFSYWKSVVLEYLYKHRNYTKITFKDIAIKTGLAISDIA 932
            |||.|::.|.:.|:|||||||||.:||.:||...::..:...|  |:.|..::|.||.:..:|:.
pombe   340 FSYELTKREHKHGSPEKPLSDLGLISYRAYWAEQIINLVLGMR--TETTIDELANKTSMTTNDVL 402

  Fly   933 LAFELLNFIKLRKNDGDIRYQINVKIEWKKVLAHHNKMANSKTRIIIEPDCLRWSP 988
            ...:.||.:|..|  |.....|:..||     ..:.::.|.|.|.|.......|.|
pombe   403 HTLQALNMLKYYK--GQFIICISDGIE-----QQYERLKNKKRRRINGDLLADWQP 451

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
enok	NP_001286823.1	H15	95..152	CDD:294056
		PHD_SF	183..>215	CDD:304600
		PHD	248..292	CDD:214584
		NAT_SF	713..989	CDD:302625	122/285 (43%)
		MOZ_SAS	768..947	CDD:280097	92/178 (52%)
		Ehrlichia_rpt	<1150..>1539	CDD:118064
mst1	NP_594630.1	SAS2	16..447	CDD:227360	154/440 (35%)
		Tudor-knot	21..74	CDD:288553	0/3 (0%)
		NAT_SF	176..451	CDD:302625	121/283 (43%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG5027
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR10615
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	3	2.910