Protein Alignment enok and KAT7

DIOPT Version :10

• Sequence 1: NP_523838.1
• Gene: enok / 37859
• FlyBaseID: FBgn0034975
• Length: 2291
• Species: Drosophila melanogaster
• Sequence 2: NP_008998.1
• Gene: KAT7 / 11143
• HGNCID: 17016
• Length: 611
• Species: Homo sapiens
• Alignment Length: 649
• Identity: 232/649 - (35%)
• Similarity: 337/649 - (51%)
• Gaps: 102/649 - (15%)

  Fly   397 RKRTFSDLSSTSSSSESEDEDDEDDDRNRNGDDNDQDESTSSDSCTSSSSDSDSSESSSDTSEWD 461
            |||     ::.|||..:||.|...|..:.:..::|.....|:....||:..|.||:.||......
Human     4 RKR-----NAGSSSDGTEDSDFSTDLEHTDSSESDGTSRRSARVTRSSARLSQSSQDSSPVRNLQ 63

  Fly   462 DEYDEEEDYDTDRST---------------IREKNVFESGKQSCAKLS------TGDGLGSPQNN 505
            ....||..|.|.|.|               :|:.....|..:.....|      |.|...||...
Human    64 SFGTEEPAYSTRRVTRSQQQPTPVTPKKYPLRQTRSSGSETEQVVDFSDRETKNTADHDESPPRT 128

  Fly   506 ELGSENWGFAAVAKNPIDIFVKS-KHNSNVKGIGYSKPAASTFATSPAANRVQKSTPVASSTPEK 569
            ..|:     |..:::.|||...: .|:.::......|.:.|..:..|...|..:|.......|..
Human   129 PTGN-----APSSESDIDISSPNVSHDESIAKDMSLKDSGSDLSHRPKRRRFHESYNFNMKCPTP 188

  Fly   570 NSAPIGGMTIKRQTANGQKKKIVPLKSMPLEAGKSYEKCEDDIPYLTEETVMKVQLLE-EIERSR 633
            ....:|.:|       |:.::...:...||....|.::|:           ::.|..: :||...
Human   189 GCNSLGHLT-------GKHERHFSISGCPLYHNLSADECK-----------VRAQSRDKQIEERM 235

  Fly   634 ETHSQADGKREMNNDEDAP-----------GESTKRAN----------------PFEN--QPLPP 669
            .:|.|.|..|.....: ||           .|..|:.|                .:.|  :||..
Human   236 LSHRQDDNNRHATRHQ-APTERQLRYKEKVAELRKKRNSGLSKEQKEKYMEHRQTYGNTREPLLE 299

  Fly   670 GVTAT-DVELYQEVLHKAVVQMSNNHIEKVNDVSLKSGQNTQSP---KSIQIGKWDIETWYSSPF 730
            .:|:. |::|::....:|     :..:||:.    ..||.|:..   |:|..|:::::|||.||:
Human   300 NLTSEYDLDLFRRAQARA-----SEDLEKLR----LQGQITEGSNMIKTIAFGRYELDTWYHSPY 355

  Fly   731 PQEYARLLKLFLCEFCLKYTKSRSVLDRHQNKCIWKQPPGTEIFRQGNISVFEVDGNVNKIYCQN 795
            |:|||||.:|::|||||||.||:::|.||..||:||.|||.||:|:|:||||||||..|||||||
Human   356 PEEYARLGRLYMCEFCLKYMKSQTILRRHMAKCVWKHPPGDEIYRKGSISVFEVDGKKNKIYCQN 420

  Fly   796 LCLLAKFFLDHKTLYYDVEPFLFYILTKNDQSGCHLVGYFSKEKHCTQKYNVSCILTMPQYQRQG 860
            ||||||.|||||||||||||||||::|:.|.:||||:|||||||:....||||||||||||.|||
Human   421 LCLLAKLFLDHKTLYYDVEPFLFYVMTEADNTGCHLIGYFSKEKNSFLNYNVSCILTMPQYMRQG 485

  Fly   861 YGRFLIDFSYLLSREEGQLGTPEKPLSDLGRLSYFSYWKSVVLEYLYKHRNYTKITFKDIAIKTG 925
            ||:.|||||||||:.|.::|:||:||||||.:||.||||.|:|.||:..:. .:|:.|:|:.:|.
Human   486 YGKMLIDFSYLLSKVEEKVGSPERPLSDLGLISYRSYWKEVLLRYLHNFQG-KEISIKEISQETA 549

  Fly   926 LAISDIALAFELLNFIKLRKNDGDIRYQINVKIEWKKVLAHHNKMANS-KTRIIIEPDCLRWSP 988
            :...||....:.|..:|..|....:..:.::..||   :|...|.:|| ||   ::|.||:|:|
Human   550 VNPVDIVSTLQALQMLKYWKGKHLVLKRQDLIDEW---IAKEAKRSNSNKT---MDPSCLKWTP 607

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
enok	NP_523838.1	PHD_SF	183..>215	CDD:473978
		PHD	248..292	CDD:214584
		PLN00104	<714..989	CDD:215056	156/276 (57%)
		PspC_subgroup_1	<1171..>1440	CDD:468201
		PRK10263	<1206..>1736	CDD:236669
KAT7	NP_008998.1	Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	1..173		41/178 (23%)
		zf-C2HC	184..212	CDD:460240	5/34 (15%)
		PLN00104	<324..609	CDD:215056	160/295 (54%)