DRSC/TRiP Functional Genomics Resources

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Protein Alignment gek and BZZ1

DIOPT Version :9

Sequence 1:NP_523837.2 Gene:gek / 37858 FlyBaseID:FBgn0023081 Length:1637 Species:Drosophila melanogaster
Sequence 2:NP_011982.1 Gene:BZZ1 / 856514 SGDID:S000001156 Length:633 Species:Saccharomyces cerevisiae


Alignment Length:737 Identity:130/737 - (17%)
Similarity:243/737 - (32%) Gaps:258/737 - (35%)


- Green bases have known domain annotations that are detailed below.


  Fly   478 LKALNDQLAALKQEKAELSKQHNEVFERLKTQ---------------DSELQDAISQRNIAMMEY 527
            ||.|.| :....:|:|:|.|.::|...||..:               |:......|.....::.:
Yeast    26 LKWLKD-IEQFYRERAKLEKDYSERLSRLSAEYFNKKSSTSVPISVGDTPTTTPGSIEAAGVVAW 89

  Fly   528 SEV---TEKLSELRNQ-----KQKLSRQVRDKEEELDGAMQKNDSLRNEL-RKSDKTRRELELHI 583
            :|:   |:.:|:..:|     :..::.|:.....:||..:.|.:...|:: .|.|....|||   
Yeast    90 NEILSQTDMISKDHDQLSTDFENHVANQLSGLFTKLDMTLSKINGFNNDMVNKKDNIYHELE--- 151

  Fly   584 EDAVIEAAKEKKLREHAEDCCRQLQMELRKGSSSVETTMPLSISSEMSSYEIERLELQFSEKLSH 648
                       |.::..::.|..::|...:.:.:                               
Yeast   152 -----------KAKKDYDEACSTMEMARNRYTKA------------------------------- 174

  Fly   649 QQTRHNMELEALREQFSELENANLALTKELQQTQERLKYTQMESITDSAETLLELKK--QHDLEK 711
            ...|:..:|:....:.::.:|..|....:..:|:::..:..:..:.|..:.:.|.|.  .:||  
Yeast   175 SNDRNKKKLDEKEMEMNKCKNEYLIKINQANRTKDKYYFQDVPEVLDLLQDVNEAKTLFLNDL-- 237

  Fly   712 SSWFEEKQRLSSEVNLKSKSLKELQAEDDEIFKELRMKREAITL------WERQMAEIIQ----W 766
              |.   :..|.|.:|.:...|.|||.:..:.:.......||.:      |:.....:.:    |
Yeast   238 --WL---KAASVENDLGANVSKRLQAANSVVKQNKPSLNTAIFIKHNLKNWKEPQDFVYKPSPVW 297

  Fly   767 VSDEKDARGYLQALATKMTEELEYLK-HVGTFNNNGVDNKNWRNRRSQKLDKMELLNLQSALQRE 830
            ..|||        .|...:.|:|.|: .:....|   |..:.:::...:|.|:..|         
Yeast   298 HDDEK--------FAVPSSLEVEDLRIKLAKAEN---DYNSLQDKTQNELSKLSTL--------- 342

  Fly   831 IQAKNMISDELSQTRSDLISTQKEVRDYKKRYDSILHDFQKKET-----------------ELRD 878
                |.|..|: :|..|.|:..| ..|..|.|.:::..|...||                 |..|
Yeast   343 ----NKIKHEM-KTNEDNINATK-FYDTLKEYLNVVSPFTSHETLKLQAEVQIESIQNNVPEEYD 401

  Fly   879 LQKGGLEYSESFLNKSTHHGLSSAFFRDMSKNSEIIDSAESFGNESGDNFTPNFFQSGNSG---- 939
            |....::.|::        ...|..|.....|...:||..|.|..:|         :||.|    
Yeast   402 LSTDNIDLSKT--------KKKSGIFSKFKHNILNVDSKPSSGGSTG---------NGNGGPLHI 449

  Fly   940 -MLFNYE--------PKYAGKNNKDHSSMKEASVSDLSREESDQLVKESQKKV------------ 983
             .|||..        |..||::: |::|::..|.:: :::.:.....:.:.||            
Yeast   450 TSLFNTSRRTRLGSAPNNAGEDS-DNNSIRTTSTNN-TKKTTQNSSDDGKNKVLYAYVQKDDDEI 512

  Fly   984 ---PGNTAIHQFLVR-TFSSPTKCNHCTSLMVGLTRQGVVCEICGFACHTICCQKVPTTCPVPMD 1044
               ||:..  ..:.| |.|..||.|:.|:...||                     ||||      
Yeast   513 TITPGDKI--SLVARDTGSGWTKINNDTTGETGL---------------------VPTT------ 548

  Fly  1045 QTKRPLGIDPTRGIGTAYEGYVKVPKSGVIKRGWIRQFVVVCDFKLFLYDISPDRCALPSVSVSQ 1109
                                |:::..:..:|                    :.||...|.|.   
Yeast   549 --------------------YIRISSAATVK--------------------ANDRGPAPEVP--- 570

  Fly  1110 VLDMRDPEFSVGSVRESDVIHA 1131
                 .|..|...||..:.|:|
Yeast   571 -----PPRRSTLPVRTMEAIYA 587

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
gekNP_523837.2 STKc_DMPK_like 98..430 CDD:270748
S_TKc 100..369 CDD:214567
KELK 478..556 CDD:292424 18/100 (18%)
CEP63 492..749 CDD:293650 43/282 (15%)
CEP63 652..880 CDD:293650 49/257 (19%)
C1_1 990..1040 CDD:278556 13/50 (26%)
PH_MRCK 1049..1182 CDD:269949 12/83 (14%)
CNH 1211..1486 CDD:279162
CRIB 1544..1580 CDD:238077
BZZ1NP_011982.1 BAR 10..256 CDD:416402 45/282 (16%)
SH3_CIP4_Bzz1_like 497..552 CDD:212711 18/103 (17%)
SH3_Bzz1_2 581..631 CDD:212712 2/7 (29%)
Blue background indicates that the domain is not in the aligned region.


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 00.000 Not matched by this tool.
eggNOG 00.000 Not matched by this tool.
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
Isobase 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 00.000 Not matched by this tool.
RoundUp 00.000 Not matched by this tool.
SonicParanoid 00.000 Not matched by this tool.
TreeFam 00.000 Not matched by this tool.
00.000

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