DRSC/TRiP Functional Genomics Resources

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back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits


Protein Alignment gek and stk38

DIOPT Version :9

Sequence 1:NP_523837.2 Gene:gek / 37858 FlyBaseID:FBgn0023081 Length:1637 Species:Drosophila melanogaster
Sequence 2:XP_031752645.1 Gene:stk38 / 100379821 XenbaseID:XB-GENE-5742605 Length:497 Species:Xenopus tropicalis


Alignment Length:472 Identity:175/472 - (37%)
Similarity:252/472 - (53%) Gaps:77/472 - (16%)


- Green bases have known domain annotations that are detailed below.


  Fly    17 KKRLTFLKCILSDTTSDQKWAAEFGEDTEGHQFSLDYLLDTFIVLYDECSNSSLRREKGVSDFLK 81
            |:|:|..|..|.:..|:   .....|:.|..|..|:..:|                |:|:.|..|
 Frog    49 KERVTMTKMTLENFYSN---LITQHEERELRQKRLEKAMD----------------EEGLRDEEK 94

  Fly    82 LSKPFVHI--------VRKLRLSRDDFDILKIIGRGAFGEVCVVQMISTEKVYAMKILNKWEMLK 138
            ..:...|.        :::.||..:||:.||:|||||||||.:||...|..|||||||.|.:||:
 Frog    95 RMRRSAHARKETEFLRLKRTRLGLEDFESLKVIGRGAFGEVRLVQKKDTGHVYAMKILRKTDMLE 159

  Fly   139 RAETACFREERDVLVFGDRQWITNLHYAFQDNINLYLVMDYYCGGDLLTLLSKFEDKLPEDMAKF 203
            :.:....|.|||:||..|..|:..:.|:|||.:||||:|::..|||::|||.| :|.|.|:..:|
 Frog   160 KEQVGHIRAERDILVEADSLWVVKMFYSFQDKLNLYLIMEFLPGGDMMTLLMK-KDTLTEEETQF 223

  Fly   204 YITEMILAINSIHQIRYVHRDIKPDNVLLDKRGHVRLADFGSCLRLDK----------------D 252
            ||.|.:|||:||||:.::||||||||:|||.:|||:|:|||.|..|.|                |
 Frog   224 YIAETVLAIDSIHQLGFIHRDIKPDNLLLDSKGHVKLSDFGLCTGLKKAHRTDFYRNLNHSLPSD 288

  Fly   253 GTVQSN------------------VAVGTPDYISPEILRAMEDGKGRYGTECDWWSLGVCMYEML 299
            ...|:.                  ..|||||||:||:.  ::.|   |...||||||||.|||||
 Frog   289 FNFQNMNSKRKAETWKRNRRQLAFSTVGTPDYIAPEVF--LQTG---YNKLCDWWSLGVIMYEML 348

  Fly   300 YGETPFYAESLVETYGKIMNHQNCFNLPSQETLNYKVSETSQDLLCKLICIPENRLGQNGIQDFM 364
            .|..||.:|:..|||.|:||.:.....|.:    ..:||.::||:.:..|..|.|:|..|:::..
 Frog   349 IGYPPFCSETPQETYKKVMNWKETLIFPPE----VPISEKAKDLILRFCCEWEQRVGAPGVEEIK 409

  Fly   365 DHPWFVGIDWKNIRQGPAPYVPEVSSPTDTSNFD-VDDNDV-RLTDSIPPSANPAFSGFHLPFIG 427
            .:.:|.|:||::||:.||....|:.|..|||||| ..|:|: :...::.......|......||.
 Frog   410 TNHFFEGVDWEHIRERPAAIPIEIKSIDDTSNFDEFPDSDILKPMGAVSNHPESEFKNKDWVFIN 474

  Fly   428 FTF----SLTSSSTLDS 440
            :|:    .||:...|.|
 Frog   475 YTYKRFEGLTARGALPS 491

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
gekNP_523837.2 STKc_DMPK_like 98..430 CDD:270748 152/367 (41%)
S_TKc 100..369 CDD:214567 130/302 (43%)
KELK 478..556 CDD:292424
CEP63 492..749 CDD:293650
CEP63 652..880 CDD:293650
C1_1 990..1040 CDD:278556
PH_MRCK 1049..1182 CDD:269949
CNH 1211..1486 CDD:279162
CRIB 1544..1580 CDD:238077
stk38XP_031752645.1 STKc_NDR1 119..494 CDD:270777 157/383 (41%)
Blue background indicates that the domain is not in the aligned region.


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 00.000 Not matched by this tool.
eggNOG 00.000 Not matched by this tool.
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 1 1.010 - - D759391at2759
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 00.000 Not matched by this tool.
RoundUp 00.000 Not matched by this tool.
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 1 1.000 - -
TreeFam 00.000 Not matched by this tool.
22.010

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