DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment snama and AT5G47430

DIOPT Version :9

Sequence 1:	NP_611884.1	Gene:	snama / 37857	FlyBaseID:	FBgn0086129	Length:	1231	Species:	Drosophila melanogaster
Sequence 2:	NP_001330705.1	Gene:	AT5G47430 / 834790	AraportID:	AT5G47430	Length:	905	Species:	Arabidopsis thaliana

Alignment Length:	973	Identity:	237/973 - (24%)
Similarity:	361/973 - (37%)	Gaps:	320/973 - (32%)

- Green bases have known domain annotations that are detailed below.

  Fly     1 MSVHYKFKSTLNFDTITFDGLHISVGDLKREIVQQKRLGKIIDFDLQITNAQSKEEYKDDGFLIP 65
            |:::|||||..::|||..||..||||.||.:|.:.|.||...|.|:.::|||:.|||.|:..|||
plant    14 MAIYYKFKSARDYDTIAMDGPFISVGILKDKIFETKHLGTGKDLDIVVSNAQTNEEYLDEAMLIP 78

  Fly    66 KNTTLIISRIP----IAHPTKKGWEP----------------PAAENAFSAAPAKQ-DNFNMDLS 109
            |||:::|.|:|    |...|.:  ||                |.|:.:.:..|..: |.|..||.
plant    79 KNTSVLIRRVPGRPRITVITTQ--EPRIQNKVEDVQAETTNFPVADPSAAEFPEDEYDEFGTDLY 141

  Fly   110 KMQGT--------------------EEDKIQAMMMQSTVDYDPKTYHRIKGQSQVG--------- 145
            .:..|                    ||.||||::....:|:..:     :||...|
plant   142 SIPDTQDAQHIIPRPHLATADDKVDEESKIQALIDTPALDWQQR-----QGQDTFGAGRGYGRGM 201

  Fly   146 --------------EVPASYRCNKCKKSGHWIKNCPFVG--GKDQQEVKRNTGIPRS-------- 186
                          ..|..|.|::|...||:|::||..|  ..|.:.||..||||:|
plant   202 PGRMNGRGFGMERKTPPPGYVCHRCNIPGHFIQHCPTNGDPNYDVKRVKPPTGIPKSMLMATPDG 266

  Fly   187 -----------FRDKPDAAENESADFVLPAVQNQ--EIPEDLICGICRDIFVDAVMI-PCCGSSF 237
                       .:...||.|.|...  ||:....  |:|.:|.|.:|:::..||.:. .||..||
plant   267 SYSLPSGAVAVLKPNEDAFEKEMEG--LPSTTRSVGELPPELKCPLCKEVMKDAALTSKCCYKSF 329

  Fly   238 CDDCVRTSLLESEDSECPDCKEKNCSPGSLIPNRFLRNSVNAFKNETGYNKSAAKPAAVKNEEKP 302
            ||.|:|..::..  |.|. |...:.....|:||:.||:::|... |.| |.|.....:|.:
plant   330 CDKCIRDHIISK--SMCV-CGRSDVLADDLLPNKTLRDTINRIL-EAG-NDSTENVGSVGH---- 385

  Fly   303 PVEKEVEKKPVAEVEPEETEVKPEKQKESETNGSNPPKSESPEPPATTEPSQKEKDKYDSDYEDN 367
                      :.::|.....               |||:.|   |.|:..|:.||....|:..|.
plant   386 ----------IPDLESARCP---------------PPKALS---PTTSVASKGEKKPVLSNNNDA 422

  Fly   368 ITIKMPQPAADSTTVPSKRSPSYSHRSESSHRRDRSDYVSDHDHKHQRPSKSESVNKDRSLLPLP 432
            .|:|.|...|:.|:.|                               |.|...:|.|       |
plant   423 STLKAPMEVAEITSAP-------------------------------RASAEVNVEK-------P 449

  Fly   433 IGTLPSYQGHMM------------AESEEARRSSA---------YKP-----------------P 459
            :....|.||.::            |..||.::..|         .||                 |
plant   450 VDACESTQGSVIVKEATVSKLNTQAPKEEMQQQVAAGEPGKKKKKKPRVPGNDMQWNPVPDLAGP 514

  Fly   460 YMQMQRGPPPMHM-------------MSHHMPAYNN---GFNNMGQRPPLSYVPYQNQSVHPMRA 508
            ...||.||.|.:.             .:...|.:|.   |||..|...|.:..|:....::||..
plant   515 DYMMQMGPGPQYFNGMQPGFNGVQPGFNGVQPGFNGFHPGFNGFGGPFPGAMPPFMGYGLNPMDM 579

  Fly   509 PYGSAGGGMNMN-----MSQPFQSPNLASIYQGVA----------AKVGSGPIDDPLEAFNRIM- 557
            .:   ||||||.     |:|.|..||:...::.:|          |.:|.    |..||.|..|
plant   580 GF---GGGMNMMHPDPFMAQGFGFPNIPPPHRDLAEMGNRMNLQRAMMGR----DEAEARNAEML 637

  Fly   558 --KEKERKKV--DRFRSSDRHR------------SRSPDRQRHRFKSPMYEKDN----------- 595
              :|.||:..  ..||..:..|            |.:|::.|.....|:::.|.
plant   638 RKRENERRPEGGKMFRDGENSRMMMNNGTSASASSINPNKSRQAPPPPIHDYDRRRRPEKRLSPE 702

  Fly   596 ----------SRDNLK------DKRPRSRERKREHSYERHIRHPRS-SRQPNDGSKS---PGGRI 640
                      |||:.:      |:|.|.|:|:|....:....|.|: .|:..|.|:.   ..|..
plant   703 HPPTRKNISPSRDSKRKSERYPDERDRQRDRERSRHQDVDREHDRTRDRRDEDRSRDHRHHRGET 767

  Fly   641 KRSGHRRSASPKPGYKSDYRDKPYNKPSAPKTEA-VEP--PPPGFEPLQLTDED---GYRNKHPT 699
            :||.|......:|         |.::|..|.|:| :|.  ....|..:...:|:   |.|.|.|:
plant   768 ERSQHHHRKRSEP---------PSSEPPVPATKAEIENNLKSSVFARISFPEEETSSGKRRKVPS 823

  Fly   700 SSEAS---QSSKGDSSKKRGENRHEEAPRKR-----HRSRSISKEPKPNDSNYRSLTPPAKIT 754
            ||..|   .|:...::...|.:.|..:.||.     :.|....:..|...|.| :.:||..::
plant   824 SSSTSVTDPSASASAAAAVGTSVHRHSSRKEIEVADYESSDEDRHFKRKPSRY-ARSPPVVVS 885

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
snama	NP_611884.1	COG5222	3..315	CDD:227547	113/399 (28%)
		DWNN	3..75	CDD:285936	36/71 (51%)
		zf-CCHC_2	148..167	CDD:290419	7/18 (39%)
		RING	217..260	CDD:238093	15/43 (35%)
AT5G47430	NP_001330705.1	None

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	1	1.000	88	1.000	Domainoid score	I2716
eggNOG	1	0.900	-	-		E1_COG5222
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	171	1.000	Inparanoid score	I1536
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0000125
OrthoInspector	1	1.000	-	-		otm2402
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR15439
Phylome	1	0.910	-	-
SonicParanoid	1	1.000	-	-		X138
SwiftOrtho	1	1.000	-	-
TreeFam	1	0.960	-	-
	11	10.920