Protein Alignment snama and Rbbp6

DIOPT Version :10

• Sequence 1: NP_611884.1
• Gene: snama / 37857
• FlyBaseID: FBgn0086129
• Length: 1231
• Species: Drosophila melanogaster
• Sequence 2: NP_001414116.1
• Gene: Rbbp6 / 308968
• RGDID: 1311964
• Length: 1827
• Species: Rattus norvegicus
• Alignment Length: 1854
• Identity: 431/1854 - (23%)
• Similarity: 661/1854 - (35%)
• Gaps: 696/1854 - (37%)

  Fly     3 VHYKFKSTLNFDTITFDGLHISVGDLKREIVQQKRLGKIIDFDLQITNAQSKEEYKDDGFLIPKN 67
            |||||.|.||:||:||||||||:.|||::|:.:::| |..|.||||||||:||||.||..|||||
  Rat     4 VHYKFSSKLNYDTVTFDGLHISLCDLKKQIMGREKL-KAADSDLQITNAQTKEEYTDDNALIPKN 67

  Fly    68 TTLIISRIPI--AHPTKKGW-----EP-----PAAENAFSAAPAKQDNFNMDLSKMQGTEEDKIQ 120
            :::|:.||||  ...|.|.:     ||     .|.:::.::....|.....:|::...:|||||:
  Rat    68 SSVIVRRIPIGGVKSTSKTYVISRTEPVMGTTKAIDDSSASISLAQLTKTANLAEANASEEDKIK 132

  Fly   121 AMMMQSTVDYDPKTYHRIKGQSQVGEVPASYRCNKCKKSGHWIKNCPFVGGKDQQ---EVKRNTG 182
            |||.||..:|||..|.:   ::.||..|.||.|.:|.|.||:|||||..|.|:.:   .:|::||
  Rat   133 AMMSQSGHEYDPINYMK---KTLVGPPPPSYTCFRCGKPGHYIKNCPTNGDKNFESGPRIKKSTG 194

  Fly   183 IPRSF------------------------------------------------------------ 187
            |||||
  Rat   195 IPRSFMMEVKDPNMKGAMLTNTGKYAIPTIDAGRLLFHKLGTMGHKQIDTYLWNRGDVYGAAATQ 259

  Fly   188 ------------RDKPDAAENESADFVLPAVQNQE---IPEDLICGICRDIFVDAVMIPCCGSSF 237
                        ::||.....|      |:..::|   ||::|:|.||:||..|||:|||||:|:
  Rat   260 ITHLREAYAIGKKEKPPFLPEE------PSSSSEEDDPIPDELLCLICKDIMTDAVVIPCCGNSY 318

  Fly   238 CDDCVRTSLLESEDSECPDCKEKNCSPGSLIPNRFLRNSVNAFKNETGYNK-------------S 289
            ||:|:||:||||::..||.|.:.:.||.:||.|:|||.:||.|||||||.|             |
  Rat   319 CDECIRTALLESDEHTCPTCHQNDVSPDALIANKFLRQAVNNFKNETGYTKRLRKQLPPPPPPIS 383

  Fly   290 AAKPAAVKNEE---KPPVEKEVEKK--PV----AEVEPEETEVKPEKQKESETNGSNPPKSESPE 345
            |.:|...:|.:   :.|:.::.:..  ||    |...|..:.:.......:.:...||..:.:|.
  Rat   384 APRPLIQRNLQPLMRSPISRQQDPLMIPVTSSSAHSTPSISSLTSNPSSLAPSVPGNPSSAPAPV 448

  Fly   346 PPATTEPS-QKEKDKYDSDYEDNITIKMPQPAADS------------------------------ 379
            |..|...| ....:|.|..:.|:....:|..|..|
  Rat   449 PDITATVSISVHSEKSDGPFRDSDNKLLPAAALASEHSKGASSIAITALMEEKGYQVPVLGTPSL 513

  Fly   380 ------------TTVPSKRS--------PSYSHRSESSH---------RRDRSDYVSDHDHKH-- 413
                        ||.|.:.:        |.:.|.::..:         |.:||.|.|.:..:|
  Rat   514 LGQSLLHGQLIPTTGPVRINAARPGGGRPGWEHSNKLGYLVSPPQQIRRGERSCYRSINRGRHHS 578

  Fly   414 QRPSKSESVNKDRSLLPLPIGTLPSYQGHMMAESEEARRSSAYKPPY-MQMQRGPPPMHMMSHHM 477
            :|..:::..:...:.:.:|:...|.|.                .||: :.:..|.||........
  Rat   579 ERSQRTQGPSLPATPVFVPVPPPPLYP----------------PPPHTLPLPPGVPPPQFSPQFP 627

  Fly   478 PAYNNGFNNMGQRPPLSYVPYQNQSVHPMRAPYGSAGGGMNMNMSQPFQSPNLASIYQGVAAKVG 542
            |         ||.||..|      ||.|...|...|      |:|.|:.|..:.:.:........
  Rat   628 P---------GQPPPAGY------SVPPPGFPPAPA------NISTPWVSSGVQTAHSNTIPTTQ 671

  Fly   543 SGPIDDPLEAF---NRIMKEKERK--KVDRF-----------RSSDRHRSRSPDRQRHRFKSPMY 591
            :.|:.  .|.|   .|.:||:|:|  |:|.|           :...:.|.||..|.:..:....|
  Rat   672 APPLS--REEFYREQRRLKEEEKKKSKLDEFTNDFAKELMEYKKIQKERRRSFSRSKSPYSGSSY 734

  Fly   592 EKDN-----SRDNLKDKRPRSRERKREH--SYERHIRHPRSSRQPNDGSKSPGGRIKRSGHRRSA 649
            .:.:     ||......|..||...|.|  ||.|...:||..|..:...:|   |.:..|:.||.
  Rat   735 SRSSYTYSKSRSGSTRSRSYSRSFSRSHSRSYSRSPPYPRRGRGKSRNYRS---RSRSHGYHRSR 796

  Fly   650 SPKPGYK---------SDYRDKPYNKPSAPKTEAV--------EPPPP---------------GF 682
            |..|.|:         ..:|.:...|.:.|:.|..        |.|||               .|
  Rat   797 SRSPPYRRYHSRSRSPQAFRGQSPTKRNVPQGETEREYFNRYREVPPPYDIKAYYGRSVDFRDPF 861

  Fly   683 E-------------------------------------------PLQLTD--------ED----- 691
            |                                           ||.:.:        ||
  Rat   862 EKERYREWERKYREWYEKYYKGYAVGAQPRPSANREDFSPERLLPLNIRNSPFTRGRREDYVAGQ 926

  Fly   692 GYRNK--------------------HPTSSEASQSS-----KGDSSKK-----RGENRHE----- 721
            .:||:                    :|.|.|....:     ||:..||     :||....
  Rat   927 SHRNRNLGGNYPEKISTRDSHNPKDNPKSKEKESENVPGDGKGNKHKKHRKRRKGEESESFLNPE 991

  Fly   722 --EAPRKRHRSRSISK--------------------EPKPNDS-NYRSLTPPAK--ITTPKMTAA 761
              |..||...|..|.:                    ||...:| .::|::...|  ...||:.:.
  Rat   992 LLETSRKSRESSGIDETKTDALFVLPSRDDATPVRDEPMDAESITFKSVSEKDKREKDKPKVKSD 1056

  Fly   762 QLRQ---------------------------RESSPK---------------------------- 771
            :.::                           ||.||:
  Rat  1057 KTKRKSDGSATAKKENVLKPSKGPQDKVDGDREKSPRSEPPLKKAKEEATKVDSVKPSSSQKDEK 1121

  Fly   772 ---TPEKSHDDYLTAKARIMASQPVINDTEMETNVGKENKAKSPLSKDRKKKKKDKDKAERKKNK 833
               ||.|:|..  :||.. ..::|| .:.:.:.:..|:.|::.|.|||.|.||.:|:|....|.:
  Rat  1122 VTGTPRKAHSK--SAKEH-QEAKPV-KEEKAKKDCSKDIKSEKPASKDEKAKKPEKNKLLESKGE 1182

  Fly   834 KDKRAKKEK-----------------------------GDRQK--------KSSS---------V 852
            |.||..:||                             ||.:|        ||:|         :
  Rat  1183 KRKRKTEEKSVDFESSSMKISKVEGTEIVKPSPKRKMEGDVEKLERTPEKDKSASSTTPAKKIKL 1247

  Fly   853 NR-SDSDINNSSLMNESNYKVLSPRAQSPSIEINAAQL--------------------------- 889
            || :...|.|:.  |.|..|..|.:.:|.|.:|...::
  Rat  1248 NRETGKKIGNAE--NPSTTKEPSEKLESTSNKIKQEKVKGKARRKVAGTEGPSSTLVDYTSTSST 1310

  Fly   890 --SPTHNATENVNPKSHSILTVGAASDDNLGPRSKLSEANSVNLSKWEIDENILGLEDSSK---- 948
              ||...:.|..:.|...|.|:...::||..|...:.....|..|||:.|:.....||..:
  Rat  1311 GGSPVRKSEEKTDTKRTVIKTMEEYNNDNTAPAEDVIIMIQVPQSKWDKDDFESEEEDDVRTTQP 1375

  Fly   949 -KAAGASDDPSEITSDVLRK---------AENAIFAKAINAIRPMEFQVIINSKDNSKDRSVVRS 1003
             ::.|   .||.|..:|..|         .||....|.....:.:..:||.:...:||  ..|.|
  Rat  1376 IQSVG---KPSSIIKNVTTKPSATVKCTEKENEQSEKIQKLTKEVSHEVIQHELRSSK--GSVSS 1435

  Fly  1004 DKDRSSSPRRNNSSRSVKDRLGTKISNDRSRSRDK-------------SKGRRRAAR------SS 1049
            :|.|:.....:.|.:...|:..|.|..|:..:.|:             ||..|.:.:      ||
  Rat  1436 EKGRAKDRDHSASEKDNPDKRKTSIQPDKESTVDRLSEQGHFKNLSQSSKETRTSEKHESVRGSS 1500

  Fly  1050 DDDANRGRS--------DRHGSRKRDNRS---RDRAAP-----------SEKRQERSYKR----- 1087
            :.|...||.        |...|::||.||   |.:.:|           |:.|:|:...:
  Rat  1501 NKDFTPGRDKKTDYDSRDYSSSKRRDERSELTRRKDSPPRSKDSLSGQKSKLREEKDLPKKGTEL 1565

  Fly  1088 ----SSPEDDKLRRQNKEQSESKHG-----KHDQNNSDDSDRRAA---KNTKSSDSRVVSSVTAV 1140
                |||..||....:|...|:|..     ..|:|...:.::.||   :|.|.|....:.|:
  Rat  1566 KKSNSSPPRDKKPHDHKASYETKRSCEETKSVDKNAGKEREKHAAEASRNGKESSGSKLPSI--- 1627

  Fly  1141 VAPPKPCRPDNPFRK----------------------------------------FVDTSSSSSL 1165
               |.|  ||.|..|                                        :.::.|.|::
  Rat  1628 ---PNP--PDPPMEKELAAGQIEKSTIKPKPQLSHSSRLSSDLTRETDEAAFEPDYNESDSESNV 1687

  Fly  1166 VVKYDNTIQ------KEGA------------SSDNGMEHRKQRD--------------KKLKKH- 1197
            .||.:..:.      ||.|            :|..|.:..:.:.              .:.:.|
  Rat  1688 SVKEEEAVASVSKDLKEKATEKATESLNVATASQPGADRSQSQSSPSVSPSRSHSPSGSQTRSHS 1752

  Fly  1198 SKYSSTDSLKSEKRKDPKSKKKSKILKKKKKSKK 1231
            |..||.:|..|:|:|..|.|||.|..||.||.||
  Rat  1753 SSASSAESQDSKKKKKKKDKKKHKKHKKHKKHKK 1786

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
snama	NP_611884.1	COG5222	3..315	CDD:227547	154/423 (36%)
		PTZ00449	<560..>778	CDD:185628	75/443 (17%)
		PRK12678	<1031..>1121	CDD:237171	31/144 (22%)
Rbbp6	NP_001414116.1	None