Protein Alignment snama and Rbbp6

DIOPT Version :10

• Sequence 1: NP_611884.1
• Gene: snama / 37857
• FlyBaseID: FBgn0086129
• Length: 1231
• Species: Drosophila melanogaster
• Sequence 2: NP_001390011.1
• Gene: Rbbp6 / 19647
• MGIID: 894835
• Length: 1828
• Species: Mus musculus
• Alignment Length: 1853
• Identity: 418/1853 - (22%)
• Similarity: 641/1853 - (34%)
• Gaps: 693/1853 - (37%)

  Fly     3 VHYKFKSTLNFDTITFDGLHISVGDLKREIVQQKRLGKIIDFDLQITNAQSKEEYKDDGFLIPKN 67
            |||||.|.||:||:||||||||:.|||::|:.:::| |..|.||||||||:||||.||..|||||
Mouse     4 VHYKFSSKLNYDTVTFDGLHISLCDLKKQIMGREKL-KAADSDLQITNAQTKEEYTDDNALIPKN 67

  Fly    68 TTLIISRIPI--AHPTKKGW-----EP-----PAAENAFSAAPAKQDNFNMDLSKMQGTEEDKIQ 120
            :::|:.||||  ...|.|.:     ||     .|.::|.::....|.....:|::...:|||||:
Mouse    68 SSVIVRRIPIGGVKSTSKTYVISRTEPVMGTTKAIDDASASISLAQLTKTANLAEANASEEDKIK 132

  Fly   121 AMMMQSTVDYDPKTYHRIKGQSQVGEVPASYRCNKCKKSGHWIKNCPFVGGKDQQ---EVKRNTG 182
            |||.||..:|||..|.:   ::.||..|.||.|.:|.|.||:|||||..|.|:.:   .:|::||
Mouse   133 AMMSQSGHEYDPINYMK---KTLVGPPPPSYTCFRCGKPGHYIKNCPTNGDKNFESGPRIKKSTG 194

  Fly   183 IPRSF------------------------------------------------------------ 187
            |||||
Mouse   195 IPRSFMMEVKDPNMKGAMLTNTGKYAIPTIDAGRLLFHKLGTMGHKQIDTYLWNRGDVYGAAATQ 259

  Fly   188 ------------RDKPDAAENESADFVLPAVQNQE---IPEDLICGICRDIFVDAVMIPCCGSSF 237
                        ::||.....|      |:..::|   ||::|:|.||:||..|||:|||||:|:
Mouse   260 ITHLREAYAIGKKEKPPFLPEE------PSSSSEEDDPIPDELLCLICKDIMTDAVVIPCCGNSY 318

  Fly   238 CDDCVRTSLLESEDSECPDCKEKNCSPGSLIPNRFLRNSVNAFKNETGYNKSAAK---------- 292
            ||:|:||:||||::..||.|.:.:.||.:||.|:|||.:||.|||||||.|...|
Mouse   319 CDECIRTALLESDEHTCPTCHQNDVSPDALIANKFLRQAVNNFKNETGYTKRLRKQLPPPPPPVP 383

  Fly   293 ---PAAVKNEE---KPPVEKEVEKK--PV----AEVEPEETEVKPEKQKESETNGSNPPKSESPE 345
               |...:|.:   :.|:.::.:..  ||    |...|..:.:.......:.:...||..:.:|.
Mouse   384 PPRPLMQRNLQPLMRSPISRQQDPLMIPVTSSSAHSAPSISSLTSNPSALAPSVSGNPSSAPAPV 448

  Fly   346 PPATTEPS-QKEKDKYDSDYEDNITIKMPQPAADS------------------------------ 379
            |..|...| ....:|.|..:.|:....:|..|..|
Mouse   449 PDITATVSISVHSEKSDGPFRDSDNKLLPAAALTSEHSKGASSIAITALMEEKGYQVPVLGTPSL 513

  Fly   380 ------------TTVPSKRS--------PSYSHRSESSH---------RRDRSDYVSDHDHKH-- 413
                        ||.|.:.:        |.:.|.::..:         |.:||.|.|.:..:|
Mouse   514 LGQSLLHGQLIPTTGPVRINAARPGGGRPGWEHSNKLGYLVSPPQQIRRGERSCYRSINRGRHHS 578

  Fly   414 QRPSKSESVNKDRSLLPLPIGTLPSYQGHMMAESEEARRSSAYKPPY-MQMQRGPPPMHMMSHHM 477
            :|..:::..:...:.:.:|:...|.|.                .||: :.:..|.||........
Mouse   579 ERSQRTQGPSLPATPVFVPVPPPPLYP----------------PPPHTLPLPPGVPPPQFSPQFP 627

  Fly   478 PAYNNGFNNMGQRPPLSYVPYQNQSVHPMRAPYGSAGGGMNMNMSQPFQSPNLASIYQGVAAKVG 542
            |         ||.||..|      ||.|...|...|      |:|.|:.|..:.:.:........
Mouse   628 P---------GQPPPAGY------SVPPPGFPPAPA------NISTPWVSSGVQTAHSNTIPTTQ 671

  Fly   543 SGPIDDPLEAF---NRIMKEKERK--KVDRF-----------RSSDRHRSRSPDRQRHRFKSPMY 591
            :.|:.  .|.|   .|.:||:|:|  |:|.|           :...:.|.||..|.:..:....|
Mouse   672 APPLS--REEFYREQRRLKEEEKKKSKLDEFTNDFAKELMEYKKIQKERRRSFSRSKSPYSGSSY 734

  Fly   592 EKDN-----SRDNLKDKRPRSRERKREH--SYERHIRHPRSSRQPNDGSKSPGGRIKRSGHRRSA 649
            .:.:     ||......|..||...|.|  ||.|...:||..|..:...:|   |.:..|:.||.
Mouse   735 SRSSYTYSKSRSGSTRSRSYSRSFSRSHSRSYSRSPPYPRRGRGKSRNYRS---RSRSHGYHRSR 796

  Fly   650 SPKPGYK---------SDYRDKPYNKPSAPKTEAV--------EPPPP---------------GF 682
            |..|.|:         ..:|.:...|.:.|:.|..        |.|||               .|
Mouse   797 SRSPPYRRYHSRSRSPQAFRGQSPTKRNVPQGETEREYFNRYREVPPPYDIKAYYGRSVDFRDPF 861

  Fly   683 E-------------------------------------------PLQLTD--------ED----- 691
            |                                           ||.:.:        ||
Mouse   862 EKERYREWERKYREWYEKYYKGYAVGAQPRPSANREDFSPERLLPLNIRNSPFTRGRREDYAAGQ 926

  Fly   692 GYRNK-----HPTSSEASQSSKGDSSKKRGENRHEEAP-------RKRHRSRSISKE-------- 736
            .:||:     :|.......|.....:.|..|...|..|       .|:||.|...:|
Mouse   927 SHRNRNLGGNYPEKLSTRDSHNAKDNPKSKEKESENVPGDGKGNKHKKHRKRRKGEESESFLNPE 991

  Fly   737 -------------------------PKPNDS-------------NYRSLTPPAK--ITTPKMTAA 761
                                     |..:|:             .::|::...|  ...||:.:.
Mouse   992 LLETSRKCRESSGIDETKTDTLFVLPSRDDATPVRDEPMDAESITFKSVSDKDKREKDKPKVKSD 1056

  Fly   762 QLRQ---------------------------RESSPK---------------------------- 771
            :.::                           ||.||:
Mouse  1057 KTKRKSDGSATAKKDNVLKPSKGPQEKVDGDREKSPRSEPPLKKAKEEATKIDSVKPSSSSQKDE 1121

  Fly   772 ----TPEKSHDDYLTAKARIMASQPVINDTEMETNVGKENKAKSPLSKDRKKKKKDKDKAERKKN 832
                ||.|:|..  :||.. ..::|. .|.:::.:..|:.|::.|.|||.|.||.:|:|....|.
Mouse  1122 KVTGTPRKAHSK--SAKEH-QEAKPA-KDEKVKKDCSKDIKSEKPASKDEKAKKPEKNKLLDSKG 1182

  Fly   833 KKDKRAKKEK-------------------------------GDRQK-----------------KS 849
            :|.||..:||                               ||.:|                 |.
Mouse  1183 EKRKRKTEEKSVDKDFESSSMKISKVEGTEIVKPSPKRKMEGDVEKLERTPEKDKIASSTTPAKK 1247

  Fly   850 SSVNR-SDSDINNSSLMNESNYKVLSPRAQSPSIEINAAQL------------------------ 889
            ..:|| :...|.|:.  |.|..|..|.:.:|.|.:|...::
Mouse  1248 IKLNRETGKKIGNAE--NASTTKEPSEKLESTSSKIKQEKVKGKAKRKVAGSEGSSSTLVDYTST 1310

  Fly   890 -----SPTHNATENVNPKSHSILTVGAASDDNLGPRSKLSEANSVNLSKWEIDENILGLED-SSK 948
                 ||...:.|..:.|...|.|:...::||..|...:.....|..|||:.|:.....|| .:.
Mouse  1311 SSTGGSPVRKSEEKTDTKRTVIKTMEEYNNDNTAPAEDVIIMIQVPQSKWDKDDFESEEEDVKTT 1375

  Fly   949 KAAGASDDPSEITSDVLRKAENAIFAKAINAIRPMEFQVI--------------------INSKD 993
            :...:...||.|..:|..|...........:.:|.:.|.:                    .:.|.
Mouse  1376 QPIQSVGKPSSIIKNVTTKPSATAKYTEKESEQPEKLQKLPKEASHELMQHELRSSKGSASSEKG 1440

  Fly   994 NSKDRSVVRSDKDRSSSPRRNNS-----SRSVKDRLGT----KISNDRSRSRDKSKGRRRAARSS 1049
            .:|||....|:||   :|.:..|     ..|..|||..    |..:..|:....|:.......||
Mouse  1441 RAKDREHSGSEKD---NPDKRKSGAQPDKESTVDRLSEQGHFKTLSQSSKETRTSEKHESVRGSS 1502

  Fly  1050 DDDANRGRS--------DRHGSRKRDNR---SRDRAAP-----------SEKRQERSYKR----- 1087
            :.|...||.        |...|::||.|   :|.:.:|           |:.|:||...:
Mouse  1503 NKDFTPGRDKKVDYDSRDYSSSKRRDERGELARRKDSPPRGKESLSGQKSKLREERDLPKKGAES 1567

  Fly  1088 ----SSPEDDKLRRQNKEQSESKHGKH-----DQNNSDDSDRRA--AKNTKSSDSRVVSSVTAVV 1141
                |||..||....:|...|:|....     |:|:..:.::.|  |:|.|.|....:..:
Mouse  1568 KKSNSSPPRDKKPHDHKAPYETKRPCEETKPVDKNSGKEREKHAAEARNGKESSGGKLPCI---- 1628

  Fly  1142 APPKPCRPDNPFRK----------------------------------------FVDTSSSSSLV 1166
              |.|  ||.|..|                                        :.::.|.|::.
Mouse  1629 --PNP--PDPPMEKELAAGQVEKSAVKPKPQLSHSSRLSSDLTRETDEAAFEPDYNESDSESNVS 1689

  Fly  1167 VKYDNTI--------------------------------QKEGASSDNGMEHRKQRDKKLKKH-S 1198
            ||.:..:                                |.:.:.|.:..........:.:.| |
Mouse  1690 VKEEEAVASISKDLKEKTTEKAKESLTVATASQPGADRSQSQSSPSVSPSRSHSPSGSQTRSHSS 1754

  Fly  1199 KYSSTDSLKSEKRKDPKSKKKSKILKKKKKSKK 1231
            ..||..|..|:|:|..|.|||.|..||.||.||
Mouse  1755 SASSAGSQDSKKKKKKKEKKKHKKHKKHKKHKK 1787

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
snama	NP_611884.1	COG5222	3..315	CDD:227547	154/423 (36%)
		PTZ00449	<560..>778	CDD:185628	71/444 (16%)
		PRK12678	<1031..>1121	CDD:237171	28/125 (22%)
Rbbp6	NP_001390011.1	COG5222	2..458	CDD:227547	162/463 (35%)
		PTZ00121	<944..1588	CDD:173412	121/652 (19%)