Protein Alignment CG10339 and NCEH1

DIOPT Version :10

• Sequence 1: NP_611881.1
• Gene: CG10339 / 37854
• FlyBaseID: FBgn0034972
• Length: 603
• Species: Drosophila melanogaster
• Sequence 2: NP_001139748.2
• Gene: NCEH1 / 57552
• HGNCID: 29260
• Length: 416
• Species: Homo sapiens
• Alignment Length: 556
• Identity: 95/556 - (17%)
• Similarity: 169/556 - (30%)
• Gaps: 189/556 - (33%)

  Fly    11 LAVFLHLVSDYCFVPVQCVDAPFIHIPGN-------GVISGTYLKMFRTQNIKAYLGIRYAHARR 68
            |...:.|.:.|.::|          :||:       .::..|:....:..|:..|||:.: |...
Human     8 LTALVALAAYYVYIP----------LPGSVSDPWKLMLLDATFRGAQQVSNLIHYLGLSH-HLLA 61

  Fly    69 FQPPDIELTPWKGIFNATVF-QPDCWQNAMPSVGKETEQILKIIQSDSSAQDAERKYEENCLYLN 132
            ..            |....| :...|.:|.          :|:..:|....:           :.
Human    62 LN------------FIIVSFGKKSAWSSAQ----------VKVTDTDFDGVE-----------VR 93

  Fly   133 VFVPDGLPEINGYAVVVWIHSGDF------STGSPADVEPF------QLVFKQKVIVVTFSYRLN 185
            ||.....||......||:||.|.:      ::.||:|...:      .:..:...::|:..|||.
Human    94 VFEGPPKPEEPLKRSVVYIHGGGWALASASASWSPSDEIRYYDELCTAMAEELNAVIVSIEYRLV 158

  Fly   186 IFGFFTTD--DGEAQGNYGLMDQSAALYWVKKNINFFGGDSNRITLMGHDAGAVSVALHMTSGEW 248
            ...:|...  |......|.|..:....|.|         |..||.:.|..||
Human   159 PKVYFPEQIHDVVRATKYFLKPEVLQKYMV---------DPGRICISGDSAG------------- 201

  Fly   249 SKGGFHKAIIMSGNPLSTVKMPYEYEGSLDQVSSTFACPRRPTSMFIQCLKRIDAKRLSENLPQV 313
                        ||..:.:...:..:.||            ...:.:|.|.....:.|..|.|..
Human   202 ------------GNLAAALGQQFTQDASL------------KNKLKLQALIYPVLQALDFNTPSY 242

  Fly   314 SWGPVVDFGLSNTSYPFIENQPEILFK------KGSYHRVPVII----GVTDMEEVLTLFKDNLD 368
            .         .|.:.|.:...  ::.|      ||:|..|..:|    ...|:||...: :..|:
Human   243 Q---------QNVNTPILPRY--VMVKYWVDYFKGNYDFVQAMIVNNHTSLDVEEAAAV-RARLN 295

  Fly   369 -TDISPSDLEGFYTDIAVTDMHKLVRNYEWCSNYELISDAINFMYANDSDTDAKKANKHIISAHT 432
             |.:.|:.....|..:..|           ..|..::.:....:.|..:...|.:|...::
Human   296 WTSLLPASFTKNYKPVVQT-----------TGNARIVQELPQLLDARSAPLIADQAVLQLL---- 345

  Fly   433 EKFYITPMQTFADLISNDSQVYSYLFRMRPRSVLQDLPSWISVPKYFDQIFVWGNPYMTNSVDWK 497
            .|.||...:  .|::.:|..:|:.........|..|         :|:..|
Human   346 PKTYILTCE--HDVLRDDGIMYAKRLESAGVEVTLD---------HFEDGF-------------- 385

  Fly   498 STDKKIADIIMTLW-ANFA---KTSNPTKSNVYVKW 529
                 ...:|.|.| .||:   :|.|.     |:||
Human   386 -----HGCMIFTSWPTNFSVGIRTRNS-----YIKW 411

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG10339	NP_611881.1	COesterase	30..560	CDD:395084	91/537 (17%)
NCEH1	NP_001139748.2	Abhydrolase_3	109..389	CDD:400284	63/382 (16%)