Protein Alignment CG10339 and Ces3a

DIOPT Version :10

• Sequence 1: NP_611881.1
• Gene: CG10339 / 37854
• FlyBaseID: FBgn0034972
• Length: 603
• Species: Drosophila melanogaster
• Sequence 2: NP_941074.1
• Gene: Ces3a / 382053
• MGIID: 102773
• Length: 571
• Species: Mus musculus
• Alignment Length: 563
• Identity: 150/563 - (26%)
• Similarity: 243/563 - (43%)
• Gaps: 73/563 - (12%)

  Fly    29 VDAPFIHIPGNGV-ISGTYLKMFRTQNIKAYLGIRYAHA----RRFQPPDIELTPWKGIFNATVF 88
            ||.|...:.|..| :..|      .:.:..:|||.:|.|    .||..| :...||:|:.:|::.
Mouse    39 VDTPLGRVRGRQVGVKDT------DRMVNVFLGIPFAQAPLGPLRFSAP-LPPQPWEGVRDASIN 96

  Fly    89 QPDCWQNA--MPSVGKETEQILKIIQSDSSAQDAERKYEENCLYLNVFVPDGLPEINGYAVVVWI 151
            .|.|.|:.  |.:......:.:||.           ...|:||.||::.|..:...:...|:|||
Mouse    97 PPMCLQDVERMSNSRFTLNEKMKIF-----------PISEDCLTLNIYSPTEITAGDKRPVMVWI 150

  Fly   152 HSGDFSTGSPADVEPFQLVFKQKVIVVTFSYRLNIFGFFTTDDGEAQGNYGLMDQSAALYWVKKN 216
            |.|....||....:...|.....|:|||..|||.||||.:|.|....||.|.:|..|||.||:.|
Mouse   151 HGGSLLVGSSTSHDGSALAAYGDVVVVTVQYRLGIFGFLSTGDKHMPGNRGFLDVVAALRWVQGN 215

  Fly   217 INFFGGDSNRITLMGHDAGAVSVALHMTSGEWSKGGFHKAIIMSGNPLSTVKMPYEYEGSLDQVS 281
            |..||||.|.:|:.|:.||.:.|:..:.| ..|.|.||:||..||..:|.:.............:
Mouse   216 IAPFGGDPNCVTIFGNSAGGIIVSSLLLS-PMSAGLFHRAISQSGVVISKILEDLNAWSEAQNFA 279

  Fly   282 STFACPRRPTSMFIQCLKRIDAKRL--SENLPQVSWGPVVDFGLSNTSY----PFIENQPEILFK 340
            ::.||.....:..:|||.:.:.|.|  .:|:              |.||    .|...:|:.|..
Mouse   280 NSVACGSASPAELVQCLLQKEGKDLITKKNV--------------NISYTVNDSFFPQRPQKLLA 330

  Fly   341 KGSYHRVPVIIGVTDME--EVLTLFKDNLD--TDISPSDLEGFYTDIAVTDMHKLVRNYEWCSNY 401
            ...:..||.::|||:.|  .:|..|.:.||  ..:|..||        :.:...|:.:.:...
Mouse   331 NKQFPTVPYLLGVTNHEFGWLLLKFWNILDKMEHLSQEDL--------LENSRPLLAHMQLPP-- 385

  Fly   402 ELISDAINFMYANDSDTDAKK-ANKHIISAHTEKFYITPMQTFADLISN-DSQVYSYLFRMRPRS 464
            |::...|:....|.||..|.: |.:.::...|   .:.|...|:..:.: ...|:.|.|:..|.|
Mouse   386 EIMPTVIDEYLDNGSDESATRYALQELLGDIT---LVIPTLIFSKYLQDAGCPVFLYEFQHTPSS 447

  Fly   465 VLQDLPSWISVPKYFDQIFVWGNPYMTNS------VDWKSTDKKIADIIMTLWANFAKTSNPTKS 523
            ..:..|:|:......:..||:|.|::|:.      .:....:|:::..:|..|:.||:|.||...
Mouse   448 FAKFKPAWVKADHSSENAFVFGGPFLTDESSLLAFPEATEEEKQLSLTMMAQWSQFARTGNPNGK 512

  Fly   524 NVYVKWNAMTPNNDSVLLIDESFNTDNLLNNQRINFWRSLYPK 566
            .: ..|..:. ..:..|.|.....|...|...|:.||....|:
Mouse   513 GL-PPWPQLN-QLEQYLEIGLEPRTGVKLKKGRLQFWTETLPR 553

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG10339	NP_611881.1	COesterase	30..560	CDD:395084	146/554 (26%)
Ces3a	NP_941074.1	COesterase	36..547	CDD:395084	147/555 (26%)
		Prevents secretion from ER. /evidence=ECO:0000255	568..571