Protein Alignment CG10339 and ace-1

DIOPT Version :10

• Sequence 1: NP_611881.1
• Gene: CG10339 / 37854
• FlyBaseID: FBgn0034972
• Length: 603
• Species: Drosophila melanogaster
• Sequence 2: NP_510660.1
• Gene: ace-1 / 181706
• WormBaseID: WBGene00000035
• Length: 620
• Species: Caenorhabditis elegans
• Alignment Length: 639
• Identity: 169/639 - (26%)
• Similarity: 271/639 - (42%)
• Gaps: 158/639 - (24%)

  Fly    21 YCFVPVQCVDAPFIHIP------GNGVISGTYLKMFRTQNIKAYLGIRYAHA----RRFQPPDIE 75
            :.|:|...:....||:.      |..|:|.|...:.|.|      ||.:|..    .||:.|..:
 Worm     8 FIFLPSTILAVDLIHLHDGSPLFGEEVLSQTGKPLTRFQ------GIPFAEPPVGNLRFKKPKPK 66

  Fly    76 LTPWKGIFNATVFQPDCWQNAMPSVGKETEQILKIIQSD---------SSAQDAERKYEENCLYL 131
             .||:...|||.....|                  |||:         |:..:|..|..|:||||
 Worm    67 -QPWRIPLNATTPPNSC------------------IQSEDTYFGDFYGSTMWNANTKLSEDCLYL 112

  Fly   132 NVFVPDGLPEINGYAVVVWIHSGDFSTGSPADVEPFQ---LVFKQKVIVVTFSYRLNIFGFFTTD 193
            ||:||..:......||:||::.|.|.:|: |.::.:.   |..::.||:|..:||::||||...:
 Worm   113 NVYVPGKVDPNKKLAVMVWVYGGGFWSGT-ATLDVYDGRILTVEENVILVAMNYRVSIFGFLYMN 176

  Fly   194 DGEAQGNYGLMDQSAALYWVKKNINFFGGDSNRITLMGHDAGAVSVALHMTSGEWSKGGFHKAII 258
            ..||.||.|:.||..|:.||.|||:.||||.:||||.|..|||.||::||.|.: |...||:|||
 Worm   177 RPEAPGNMGMWDQLLAMKWVHKNIDLFGGDLSRITLFGESAGAASVSIHMLSPK-SAPYFHRAII 240

  Fly   259 MSGNPLSTVKMPYEYE------------------GSLDQVSSTFACPRRPTSMFIQCLKRIDAKR 305
            .||:..|    |:..|                  |::..::..:       ...:.|.:|.||..
 Worm   241 QSGSATS----PWAIEPRDVALARAVILYNAMKCGNMSLINPDY-------DRILDCFQRADADA 294

  Fly   306 LSENLPQVSWGPVVDFGLSNTSYPFI---------ENQPEILFKKGSYHRVPVIIGVTDMEEVLT 361
            |.||    .|.||.:||    .:|::         ||....| |:|::.:..::.| ::.:|.:.
 Worm   295 LREN----EWAPVREFG----DFPWVPVVDGDFLLENAQTSL-KQGNFKKTQLLAG-SNRDESIY 349

  Fly   362 LFKDNLDTDISPSDLEGFYTDIAVTDMHK------------LVRNYEWCS--------NYE---- 402
            .....| .||.|  :..|:|.   ||..|            |.|....|.        .||
 Worm   350 FLTYQL-PDIFP--VADFFTK---TDFIKDRQLWIKGVKDLLPRQILKCQLTLAAVLHEYEPQDL 408

  Fly   403 --LISDAINFMYANDSDTDAKKANKHIISAHTEKFYITPMQTFADLISNDSQVYSYLFRMRPRSV 465
              ...|.||.|.....|.....:...:..|||:               :....|.|.|..|...
 Worm   409 PVTPRDWINAMDKMLGDYHFTCSVNEMALAHTK---------------HGGDTYYYYFTHRASQ- 457

  Fly   466 LQDLPSWISVPKYFDQIFVWGNPYMTNSVDWKSTDKKIADIIMTLWANFAKTSNPTKS------- 523
             |..|.|:.|...::..|::|.|......::...::::::..|..|||||||.:|.|:
 Worm   458 -QTWPEWMGVLHGYEINFIFGEPLNQKRFNYTDEERELSNRFMRYWANFAKTGDPNKNEDGSFTQ 521

  Fly   524 NVYVKWNAMTPNNDSVLLIDESFNTDNLLNN----QRINFWRSLYPKILVFSAD 573
            :|:.|:|:::....: :.::.|:.:...:.:    :...||::..|.::...||
 Worm   522 DVWPKYNSVSMEYMN-MTVESSYPSMKRIGHGPRRKECAFWKAYLPNLMAAVAD 574

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG10339	NP_611881.1	COesterase	30..560	CDD:395084	162/615 (26%)
ace-1	NP_510660.1	Esterase_lipase	20..543	CDD:238191	161/594 (27%)