Protein Alignment CG10339 and cest-3

DIOPT Version :10

• Sequence 1: NP_611881.1
• Gene: CG10339 / 37854
• FlyBaseID: FBgn0034972
• Length: 603
• Species: Drosophila melanogaster
• Sequence 2: NP_510042.2
• Gene: cest-3 / 181385
• WormBaseID: WBGene00008451
• Length: 588
• Species: Caenorhabditis elegans
• Alignment Length: 573
• Identity: 135/573 - (23%)
• Similarity: 231/573 - (40%)
• Gaps: 146/573 - (25%)

  Fly    38 GNGVISGTYLKM-FRTQNIKAYLGIRYAHAR------RFQPPDIELTPWKGIFNATVFQPDCWQN 95
            |..:||.||.|: .:|.|:..::......|:      ||..|: ...|||.|.|||.:.|.|:.|
 Worm    20 GQRIISTTYGKLEGKTVNVDQHMFKNVPFAKPPLGKLRFSLPE-WTNPWKNIRNATEYSPSCFSN 83

  Fly    96 AMPSVGKETEQILKIIQSDSSAQDAERKYEENCLYLNVFVPDGLPEINGYAVVVWIHSGDFSTGS 160
            :.             :::||:.    ....|:|||||||..:...:....:.||:.|.|..:..|
 Worm    84 SS-------------MRTDSNF----FPMSEDCLYLNVFTNEYCLKSKNCSTVVYYHGGGINMDS 131

  Fly   161 PA---DVEPFQLVFKQKVIVVTFSYRLNIFG--FFTTDDGEAQGNYGLMDQSAALYWVKKNINFF 220
            ..   |....:...|:.|:.:..:|||.|||  :|.:::...| |..:.|...||.::.:.|:.|
 Worm   132 AVQFNDTFILERYVKENVVFIIPAYRLGIFGLLYFGSNNLVPQ-NLAIHDCELALRFIHQEISNF 195

  Fly   221 GGDSNRITLMGHDAGA-VSVALHMTSGEWSKGGF-------HKAI--IMSGNPLSTVKMP----- 270
            ||..:.|.||||.||| :|:..          ||       ||.|  |:..:|:.:..||
 Worm   196 GGHKDDINLMGHSAGAHISLIF----------GFSRHIDPDHKLINRIIVLSPVPSYDMPELLIK 250

  Fly   271 --YEYEGSLDQVSSTFACPRRPTSM----FIQCLKRIDAK------RLSENLPQVSWGPVVDFGL 323
              |::       :....|.:|..:.    .::||::.||:      ||.||.....|..:
 Worm   251 NCYDF-------AERVGCYKRNVTARDTEIVKCLRKKDARGLMSMQRLMENDRLYFWNFL----- 303

  Fly   324 SNTSYPFIENQPEIL-FKKGSYHRVPVIIGVTDMEEVLTLFKDNLDTDISPSDLEGFYTDIAVTD 387
              ...||:.....|. ||:.:..|..:|....|..:...|.|:|      |: :.|.:.|
 Worm   304 --AGEPFMYRDESIADFKEYAVKRDMLIGNTVDEVKWKRLKKEN------PA-IAGSFMD----- 354

  Fly   388 MHKLVRNYEWCSNYELISDAINFMYANDSDTDAKKANKHIISAHTEKFYITPMQTFADLISN-DS 451
                     |.:.|| ::...||.:      |:...|. ...:.|:..::: ..|:|:..:| ..
 Worm   355 ---------WENPYE-VAHKFNFYH------DSAPVNS-TYESFTQGIFVS-TATYAEAQANAGG 401

  Fly   452 QVYSYLFRMRPRSVLQDLPSWISVPKYFDQIFVWGNPYMTNSVDWKSTDKKIADIIMT-LWANFA 515
            .||.:....:|.|.:.|:           |.||.     |:..|:.::|..|.|...: :..||.
 Worm   402 TVYLFQSNQQPSSHVSDM-----------QYFVG-----THREDYHTSDMDIMDTFYSKMIVNFT 450

  Fly   516 KTSNPTKSNVYVKWNAMTPNNDSVLLIDESFNTDNLL--------NNQRINFW 560
            |..:|:.     .|..:.|:..:...::  .||:..:        :...:|||
 Worm   451 KFGSPSP-----VWEPLVPSRMNYYALE--VNTEKGIWPRMEEDFHESDVNFW 496

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG10339	NP_611881.1	COesterase	30..560	CDD:395084	133/571 (23%)
cest-3	NP_510042.2	alpha/beta hydrolases	21..496	CDD:473884	132/570 (23%)