Protein Alignment CG10339 and cest-16

DIOPT Version :10

• Sequence 1: NP_611881.1
• Gene: CG10339 / 37854
• FlyBaseID: FBgn0034972
• Length: 603
• Species: Drosophila melanogaster
• Sequence 2: NP_741812.2
• Gene: cest-16 / 180905
• WormBaseID: WBGene00020330
• Length: 697
• Species: Caenorhabditis elegans
• Alignment Length: 661
• Identity: 144/661 - (21%)
• Similarity: 258/661 - (39%)
• Gaps: 166/661 - (25%)

  Fly    42 ISGTYLKMFRTQNIKAYLGIRYAH----ARRFQPPDIELTPWKGIFNATVFQPDCWQNAMPSVGK 102
            |.|.::::||        |:.||.    ..||:|| ::.|.|.....|..:.|.|.
 Worm    40 IDGKHIQIFR--------GVPYAEPPIGELRFKPP-VKKTRWHQELPAVEYGPPCL--------- 86

  Fly   103 ETEQILKIIQSDSSAQDAERKYEENCLYLNVFVP-DGLPEINGYAVVVWIHSGDFSTGSP---AD 163
               |.:...::|..|:....:..|:|||||||.| |...|...|.::||||.|.|..||.   .|
 Worm    87 ---QFMDFHKNDKFAKTNMDRQSEDCLYLNVFSPYDTDDESKTYPILVWIHGGSFLAGSADTGID 148

  Fly   164 VEPFQL-VFKQKVIVVTFSYRLNIFGFFTTDDGE-AQGNYGLMDQSAALYWVKKNINFFGGDSNR 226
            :|.... :..:.:..|:.:|||...||....:|: .:||:|:.|...||.|::.||..|.||..:
 Worm   149 MEVIAANIVSKGIAFVSINYRLGPLGFMNYQNGDKLEGNFGIWDMVMALQWIQSNIKQFNGDPTK 213

  Fly   227 ITLMGHDAGAVSVALHMTSGEWSKGGFHKAIIMSGNPLS--TVKMPYEYEGSLDQVSSTFACPR- 288
            :|:||..||..:.:|...|.:.| |..|:||||||:.::  .:....:...|:|.:.:.|.|.:
 Worm   214 VTVMGESAGGAASSLLALSPKTS-GLLHQAIIMSGSSMAGWAIHRHSQPAYSVDNLVAYFRCEKW 277

  Fly   289 ---------------------------RPTSMFIQCL----KRID-----AKRLSENLPQVSWGP 317
                                       ...::.|.||    .::|     .|.|:.:.|......
 Worm   278 INEDDTKEVVGDEYQHLTHSVIRSALCNYQNVKINCLTDDMTQMDKMNCLRKELNFSSPLFRKAL 342

  Fly   318 VVDFGLS----------NTSYPFIENQPEILFKKGSYHRVPVIIGVTDME--EVLTLFKDNLDTD 370
            ..:.|:|          ::....:.|..          |:|::.||...|  ....:|.:....|
 Worm   343 AAELGVSKMVVDGDLVPSSGVSLVRNNA----------RIPIMTGVARKEWGHKKAMFYNMHQRD 397

  Fly   371 -ISPSDLEGFYTDIAVTDMH------------KLVRN-----YEWCSNYELISD-AINFMYANDS 416
             :..||:|.....|.....|            :|:.|     |....|.|.|:| .:..:...:|
 Worm   398 GLKRSDVEEQVYRIIDNSFHETASEKLANSTVQLIANATIVRYLETPNNEFIADQVVGALQKLES 462

  Fly   417 DTDAKKANKHIISAHTEKFYITPMQTF-----ADLISNDSQVYSYLFRMRPRSVLQDLPSWISVP 476
            |.:.....:..::|:.:|.....:.:|     :.::.::.::|| ||..:|..:.:...|.|...
 Worm   463 DIEFVAPCEREVAAYVDKGVPVYLYSFDYVPKSPILESERKIYS-LFGTKPVEMKRTEKSEILEK 526

  Fly   477 KYF---DQIFVWGNPYMTN--SVDWKSTDKKIADIIMTLWANFAKTSNPTKSNVYVKWNAMTPNN 536
            ..|   |..|::...|.:|  ...:...::.::.|:.|:..||.|..:|  |.....|...:.|:
 Worm   527 AAFHGLDHAFIFSKGYSSNFEISPYTKREETMSKILCTMLTNFVKNGDP--STTRFSWPIFSGNS 589

  Fly   537 DSVLLID---------------ESFNTD--------------------NLLNNQRINF------W 560
            ...:.:|               :.:||:                    :|.|.:|:..      |
 Worm   590 SQYVSLDVPLKLLEGEIHFPDAQFWNTEAELITRYVSKDSETDLDPDADLTNEERVQLSAYRRSW 654

  Fly   561 RSLYPKILVFS 571
            .:|:..:::.|
 Worm   655 YALWVLVIILS 665

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG10339	NP_611881.1	COesterase	30..560	CDD:395084	141/648 (22%)
cest-16	NP_741812.2	alpha/beta hydrolases	23..608	CDD:473884	136/602 (23%)