Protein Alignment CG10339 and cest-33

DIOPT Version :10

• Sequence 1: NP_611881.1
• Gene: CG10339 / 37854
• FlyBaseID: FBgn0034972
• Length: 603
• Species: Drosophila melanogaster
• Sequence 2: NP_504621.1
• Gene: cest-33 / 179020
• WormBaseID: WBGene00017431
• Length: 554
• Species: Caenorhabditis elegans
• Alignment Length: 555
• Identity: 136/555 - (24%)
• Similarity: 220/555 - (39%)
• Gaps: 117/555 - (21%)

  Fly    55 IKAYLGIRYAH----ARRFQPPDIELTPWKGIFNATVFQPDCWQNAMPSVGKETEQILKIIQSDS 115
            :..||||.||.    ..||:.| :.:..|..|.:...:.|.|.|..      ..|||
 Worm    36 VDGYLGIPYAKPPVGELRFKKP-VTVDVWTEIKDCYKYGPACVQTG------GFEQI-------- 85

  Fly   116 SAQDAERKYEENCLYLNVFVP-DGLPEI-NGYAVVVWIHSGDFSTGSPADVEPFQL---VFKQKV 175
            :........|..||.||||.| :...|. ||..|:|:||.|.:...:.:|...:.|   :..:.|
 Worm    86 AGPRTPTPEEAGCLTLNVFTPRNASSEFKNGRPVMVYIHGGGYELCASSDFCAYSLSGTLPLKDV 150

  Fly   176 IVVTFSYRLNIFGFFTTDDGEAQGNYGLMDQSAALYWVKKNINFFGGDSNRITLMGHDAGAVSVA 240
            :||:.:|||.:|||.||.|....||:||.||:.||.||:|:|:.||||.|.:|:.|..||..|..
 Worm   151 VVVSINYRLGVFGFLTTGDNVCPGNFGLWDQTLALKWVQKHISSFGGDPNCVTVFGQSAGGASTD 215

  Fly   241 LHMTSGEWSKGGFHKAIIMSGNPLSTVKMPYEYEGSLDQ--VSSTFA-----CPRRPTSMFIQCL 298
            | ::....|:..|.:.|.:||    |....:....|.:|  :...||     ..|..:::|
 Worm   216 L-LSLSPHSRDLFQRFIPISG----TAHCDFAIRASENQAKIFREFAEFHGFSGRDSSALF---- 271

  Fly   299 KRIDAKRLSENLPQVSWGPVVDFGLSNTS---------YPFIENQPEILFKK------GSYHRVP 348
                 |...|..|:.         |||..         ..||.|.....|.|      ....:..
 Worm   272 -----KWYQEQSPET---------LSNVKGYKKSISGFLTFIPNLDGDFFPKPLDELRKEAPKKQ 322

  Fly   349 VIIGVTDMEEVLTLFKDNLDTDISPSDLEGFYTDIAVTDMHKLVRNYEWCSNYELISDAINFMYA 413
            ::.|||:.|.::..   :::...||:       |:.:|.|.:.:...:..||.:.|.......|.
 Worm   323 MMTGVTEYEGLMLA---SMNPAFSPA-------DVGLTLMPQGIYGKDVVSNPDEIQKIFYEKYV 377

  Fly   414 NDSD-TDAKKANKHIISAHTEKFY-ITPMQTFADLISNDSQVYSYLFR-MRPRSVLQDLPSWISV 475
            ...| :|.....|.:..|..::|: :..:|...:...:.::||.|.|. :.|.|    ...|..:
 Worm   378 EGVDKSDELAMRKKLCEALGDEFFNVGVIQAAKNAAKHGNEVYFYTFEYVNPDS----FGMWDGM 438

  Fly   476 PKYFDQIFVWGNPYMT-----NSVDWKSTDKKIADIIMTLWANFAKTSNP----TKSNVYVKWNA 531
            ..:...:......|:.     :..:....|:|:.:...||::||||..||    ..:.::.|::.
 Worm   439 MPFKAAVHCTELRYLLGEGVYSKFEPTEEDRKVMETTTTLFSNFAKYGNPNGKGATAEIWEKYSL 503

  Fly   532 MTPNNDSVLLIDESFNTDNLLNNQRINFWRSLYPK 566
            ..|.                      ..:|..|||
 Worm   504 NRPE----------------------RHYRISYPK 516

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG10339	NP_611881.1	COesterase	30..560	CDD:395084	132/547 (24%)
cest-33	NP_504621.1	Esterase_lipase	16..521	CDD:238191	136/555 (25%)