Protein Alignment CG10339 and Bche

DIOPT Version :10

• Sequence 1: NP_611881.1
• Gene: CG10339 / 37854
• FlyBaseID: FBgn0034972
• Length: 603
• Species: Drosophila melanogaster
• Sequence 2: NP_001415300.1
• Gene: Bche / 12038
• MGIID: 894278
• Length: 615
• Species: Mus musculus
• Alignment Length: 586
• Identity: 161/586 - (27%)
• Similarity: 248/586 - (42%)
• Gaps: 123/586 - (20%)

  Fly    41 VISGTYLKMFRTQNIKAYLGIRYAH----ARRFQPPDIELTPWKGIFNATVFQPDCWQN---AMP 98
            |:.||         :.|:|||.||.    :.||:.|. .|..|..|.|||.:...|:||   |.|
Mouse    61 VLGGT---------VTAFLGIPYAQPPLGSLRFKKPQ-PLNKWPDIHNATQYANSCYQNIDQAFP 115

  Fly    99 SVGKETEQILKIIQSDSSAQDAERKYEENCLYLNVFVPDGLPEINGYAVVVWIHSGDFSTGS--- 160
            ..            ..|...:......|:||||||::|  :|:.....|:|||:.|.|.||:
Mouse   116 GF------------QGSEMWNPNTNLSEDCLYLNVWIP--VPKPKNATVMVWIYGGGFQTGTSSL 166

  Fly   161 PADVEPFQLVFKQKVIVVTFSYRLNIFGFFT-TDDGEAQGNYGLMDQSAALYWVKKNINFFGGDS 224
            |.....| |...::||||:.:||:...||.. ..:.:|.||.||.||..||.||::||..|||:.
Mouse   167 PVYDGKF-LARVERVIVVSMNYRVGALGFLAFPGNPDAPGNMGLFDQQLALQWVQRNIAAFGGNP 230

  Fly   225 NRITLMGHDAGAVSVALHMTSGEWSKGGFHKAIIMSG--NPLSTVKMPYEYEGSLDQVSSTFACP 287
            ..||:.|..|||.||:||:...: |...|.:||:.||  |....||.|.|.......::....|.
Mouse   231 KSITIFGESAGAASVSLHLLCPQ-SYPLFTRAILESGSSNAPWAVKHPEEARNRTLTLAKFTGCS 294

  Fly   288 RRPTSMFIQCLKRIDAKRL---------SENLPQVSWGPVVDFGLSNTSYPFIENQPEILFKKGS 343
            :......|:||:..|.:.:         |:::..:::||.||       ..|:.:.|..|.:.|.
Mouse   295 KENEMEMIKCLRSKDPQEILRNERFVLPSDSILSINFGPTVD-------GDFLTDMPHTLLQLGK 352

  Fly   344 YHRVPVIIGVTDMEEVLTLF-------KDNLDTDISPSDL-EG------------------FYTD 382
            ..:..:::||...|....|.       ||| |:.|:..:. ||                  :|.|
Mouse   353 VKKAQILVGVNKDEGTAFLVYGAPGFSKDN-DSLITRKEFQEGLNMYFPGVSRLGKEAVLFYYVD 416

  Fly   383 IAVTDMHKLVRNY--EWCSNYELISDAINFMYANDSDTDAKKANKHIISAHTEKFYITPMQTFAD 445
            .......::.|:.  :...:|.:|..|:.|                     |:|        ||:
Mouse   417 WLGEQSPEVYRDALDDVIGDYNIICPALEF---------------------TKK--------FAE 452

  Fly   446 LISNDSQVYSYLFRMRPRSVLQDLPSWISVPKYFDQIFVWGNPYMTNSVDWKSTDKKIADIIMTL 510
            |.:|   .:.|.|..|...:  ..|.|:.|...::..||:|.| :...|::...::..:..||..
Mouse   453 LENN---AFFYFFEHRSSKL--PWPEWMGVMHGYEIEFVFGLP-LGRRVNYTRAEEIFSRSIMKT 511

  Fly   511 WANFAKTSNP--TKSNVYVKWNAMTPNNDSVLLID-ESFNTDNLLNNQRINFWRSLYPKILVFSA 572
            ||||||..:|  |:.| ...|...|......|.:: |.....:.|...:..|||..:||:|..:.
Mouse   512 WANFAKYGHPNGTQGN-STMWPVFTSTEQKYLTLNTEKSKIYSKLRAPQCQFWRLFFPKVLEMTG 575

  Fly   573 D 573
            |
Mouse   576 D 576

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG10339	NP_611881.1	COesterase	30..560	CDD:395084	154/571 (27%)
Bche	NP_001415300.1	COesterase	43..563	CDD:395084	154/571 (27%)
		AChE_tetra	578..612	CDD:430146