Protein Alignment CG10339 and Nlgn1

DIOPT Version :10

• Sequence 1: NP_611881.1
• Gene: CG10339 / 37854
• FlyBaseID: FBgn0034972
• Length: 603
• Species: Drosophila melanogaster
• Sequence 2: XP_038957495.1
• Gene: Nlgn1 / 116647
• RGDID: 621117
• Length: 863
• Species: Rattus norvegicus
• Alignment Length: 601
• Identity: 168/601 - (27%)
• Similarity: 264/601 - (43%)
• Gaps: 118/601 - (19%)

  Fly    58 YLGIRYA----HARRFQPPDIELTPWKGIFNATVFQPDCWQNAMPSVGKETEQILKIIQSD---- 114
            :||:.||    ...|||||: ..:||..|.|||.|.|.|.||.:.  |:..|.:|.:..::
  Rat    80 FLGVPYAAPPTGEHRFQPPE-PPSPWSDIRNATQFAPVCPQNIID--GRLPEVMLPVWFTNNLDV 141

  Fly   115 --SSAQDAERKYEENCLYLNVFVP-------------------------------DGLPEINGYA 146
              |..||    ..|:|||||::||                               |.|.: |..|
  Rat   142 VSSYVQD----QSEDCLYLNIYVPTEDVKRISKECARKPGKKICRKGGPLTKTQTDDLGD-NDRA 201

  Fly   147 -------------VVVWIHSGDFSTGSPADVEPFQLVFKQKVIVVTFSYRLNIFGFFTTDDGEAQ 198
                         |:|:||.|.:..|:....:...|.....|||:|.:|||.:.||.:|.|..|:
  Rat   202 EDEDIRDSGGPKPVMVYIHGGSYMEGTGNLYDGSVLASYGNVIVITVNYRLGVLGFLSTGDQAAK 266

  Fly   199 GNYGLMDQSAALYWVKKNINFFGGDSNRITLMGHDAGAVSVAL----HMTSG-EWS---KGGFHK 255
            |||||:|...||.|..:||.|||||..|||:.|..||...|.|    |.:.| .||   ||.|.:
  Rat   267 GNYGLLDLIQALRWTSENIGFFGGDPLRITVFGSGAGGSCVNLLTLSHYSEGNRWSNSTKGLFQR 331

  Fly   256 AIIMSGNPLSTVKMPYEYEGSLDQVSSTFACPRRPTSMFIQCLKRIDAKRLSENLPQ-----VSW 315
            ||..||..||:..:.::.......:::...|....|...::||::...|.|.:...|     :::
  Rat   332 AIAQSGTALSSWAVSFQPAKYARILATKVGCNVSDTVELVECLQKKPYKELVDQDVQPARYHIAF 396

  Fly   316 GPVVDFGLSNTSYPFIENQPEILFKKGSYHRVPVIIGVTDMEEVLTLFKDNL---DTDISPSDLE 377
            |||:|..:       |.:.|:||.::|.:....:::||...|.:  .|.:|:   |..:|.||.
  Rat   397 GPVIDGDV-------IPDDPQILMEQGEFLNYDIMLGVNQGEGL--KFVENIVDSDDGVSASDF- 451

  Fly   378 GFYTDIAVTDMHKLVRN-YEWCSNYELISDAINFMYANDSDT-DAKKANKHIISAHTEKFYITPM 440
                |.||::   .|.| |.:....:::.:.|.|||.:.:|. :.:...|.:::..|:..::.|.
  Rat   452 ----DFAVSN---FVDNLYGYPEGKDVLRETIKFMYTDWADRHNPETRRKTLLALFTDHQWVAPA 509

  Fly   441 QTFADLISN-DSQVYSYLFRMRPRSVLQDLPSWISVPKYFDQIFVWGNPYMTNS----VDWKSTD 500
            ...|||.|| .|..|.|.|....::  ..:|:|.......:..:|.|.|.:..:    .::...|
  Rat   510 VATADLHSNFGSPTYFYAFYHHCQT--DQVPAWADAAHGDEVPYVLGIPMIGPTELFPCNFSKND 572

  Fly   501 KKIADIIMTLWANFAKTSNP------------TKSNVY--VKWNAMTPNNDSVLLIDESFNTDNL 551
            ..::.::||.|.|||||.:|            ||.|.:  |.|...:..:...|.|.........
  Rat   573 VMLSAVVMTYWTNFAKTGDPNQPVPQDTKFIHTKPNRFEEVAWTRYSQKDQLYLHIGLKPRVKEH 637

  Fly   552 LNNQRINFWRSLYPKI 567
            ....::|.|..|.|.:
  Rat   638 YRANKVNLWLELVPHL 653

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG10339	NP_611881.1	COesterase	30..560	CDD:395084	165/592 (28%)
Nlgn1	XP_038957495.1	COesterase	52..646	CDD:395084	165/592 (28%)