Protein Alignment CG10339 and Ces1d

DIOPT Version :10

• Sequence 1: NP_611881.1
• Gene: CG10339 / 37854
• FlyBaseID: FBgn0034972
• Length: 603
• Species: Drosophila melanogaster
• Sequence 2: NP_579829.3
• Gene: Ces1d / 113902
• RGDID: 70896
• Length: 565
• Species: Rattus norvegicus
• Alignment Length: 579
• Identity: 148/579 - (25%)
• Similarity: 259/579 - (44%)
• Gaps: 110/579 - (18%)

  Fly    40 GVISGTYLKM--FRTQNIKAYLGIRYAH----ARRFQPPDIELTPWKGIFNATVFQPDCWQNAMP 98
            |.:.|.|:.:  | .|.:..:|||.:|.    :.||.||. ...||..:.|.|.:.|.|.|:|:.
  Rat    31 GKVLGKYVNLEGF-AQPVAVFLGIPFAKPPLGSLRFAPPQ-PAEPWNFVKNTTSYPPMCSQDAVG 93

  Fly    99 SVGKETEQILKIIQSDSSAQDAERKYEENCLYLNVFVPDGLPEINGYAVVVWIHSGDFSTGSPAD 163
            .      |:|..:.::.. ::...::.|:||||||:.|..|.:.:...|:||||.|....|..:.
  Rat    94 G------QVLSELFTNRK-ENIPLQFSEDCLYLNVYTPADLTKNSRLPVMVWIHGGGLVVGGAST 151

  Fly   164 VEPFQLVFKQKVIVVTFSYRLNIFGFFTTDDGEAQGNYGLMDQSAALYWVKKNINFFGGDSNRIT 228
            .:...|...:.|:|||..|||.|:|||:|.|..:|||:|.:||.|||:||:.||..|||:...:|
  Rat   152 YDGQVLSAHENVVVVTIQYRLGIWGFFSTGDEHSQGNWGHLDQVAALHWVQDNIANFGGNPGSVT 216

  Fly   229 LMGHDAGAVSVALHMTSGEWSKGGFHKAIIMSGNPLSTVKMPYEYEGSLDQVSSTFACPRRPTSM 293
            :.|..||..||:..:.| ..:|..||:||..||..|::..:..:.:...:.:::...|....:::
  Rat   217 IFGESAGGFSVSALVLS-PLAKNLFHRAISESGVVLTSALITTDSKPIANLIATLSGCKTTTSAV 280

  Fly   294 FIQCLKRIDAKRLSENLPQVSWGPVVDFGLSNTSYPF---------IENQPEILFKKGSYHRVPV 349
            .:.||::.....|.|...:::...:...|....||||         :...||.:..:.|::.||.
  Rat   281 MVHCLRQKTEDELLETSLKLNLFKLDLLGNPKESYPFLPTVIDGVVLPKTPEEILTEKSFNTVPY 345

  Fly   350 IIGVTDME---EVLTLF-----KDNLDTDISPSDLEGFYTDIAVTDMHKLVRNYEWCSNYELISD 406
            |:|:...|   .:.||.     :..||...:.|.|...|..:.:::  |::             .
  Rat   346 IVGINKQEFGWIIPTLMGYPLSEGKLDQKTAKSLLWKSYPTLKISE--KMI-------------P 395

  Fly   407 AINFMYANDSDTDAKKANKHIISAHTEKFYITPMQTFADLISN-------------------DSQ 452
            .:...|...:|..||:.:                 .|.||:::                   .:.
  Rat   396 VVAEKYFGGTDDPAKRKD-----------------LFQDLVADVMFGVPSVMVSRSHRDAGAPTF 443

  Fly   453 VYSYLFR------MRPRSVLQDLPSWISVPKYFDQIF-VWGNPYMTNSVDWKSTDKKIADIIMTL 510
            :|.:.:|      |||::|:.|         :.|::| |:|:|::.:....:.|:  ::.::|..
  Rat   444 MYEFEYRPSFVSAMRPKTVIGD---------HGDELFSVFGSPFLKDGASEEETN--LSKMVMKY 497

  Fly   511 WANFAKTSNPTKSNVYVKWNAMTPNND---SVLLIDESFNTDNLLNNQRINFWRSLYPK 566
            |||||:..:|....: ..|    |..|   ..|.|..|......|.::.:.||..|..|
  Rat   498 WANFARNGSPNGGGL-PHW----PEYDQKEGYLKIGASTQAAQRLKDKEVAFWSELRAK 551

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG10339	NP_611881.1	COesterase	30..560	CDD:395084	144/571 (25%)
Ces1d	NP_579829.3	COesterase	22..545	CDD:395084	144/571 (25%)
		Prevents secretion from ER. /evidence=ECO:0000255	562..565