DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Mlp60A and WLIM2b

DIOPT Version :9

Sequence 1:	NP_001137750.1	Gene:	Mlp60A / 37853	FlyBaseID:	FBgn0259209	Length:	486	Species:	Drosophila melanogaster
Sequence 2:	NP_001190099.1	Gene:	WLIM2b / 824743	AraportID:	AT3G55770	Length:	233	Species:	Arabidopsis thaliana

Alignment Length:	218	Identity:	54/218 - (24%)
Similarity:	79/218 - (36%)	Gaps:	73/218 - (33%)

- Green bases have known domain annotations that are detailed below.

  Fly    10 KCPACGKSVYAAEERVAGGYKFHKTCFKCSMCNKALDSTNCTEHEKELFCKNCHGRKYGPKGYGF 74
            ||.||.|:|||.|...|.|..:||:||||:.|...|..::.:..|..|:||....:.:...|
plant     9 KCKACEKTVYAVELLSADGVGYHKSCFKCTHCKSRLQLSSYSSMEGVLYCKPHFEQLFKESG--- 70

  Fly    75 GGGAGCLSTDTGAHLNREFVPP-----KIPP---KAPDGLG---------CPRCGIYVYAAEQM- 121
                         ..|:.|..|     |..|   :.|..:.         |..|...||..|::
plant    71 -------------SFNKNFQSPAKSADKSTPELTRTPSRVAGRFSGTQEKCATCSKTVYPIEKIH 122

  Fly   122 -------LAR--------------------------GKGYHRRCFKCVQ--CNKTLDSTLHCDGP 151
                   |||                          .:.||:.||||..  |..:..:....:|
plant   123 NPLSYRELARKPNVLHRCIDPGDIGSCYFNLHVTVESQTYHKSCFKCSHGGCPISPSNYAALEG- 186

  Fly   152 DKDIYCRGCYAQKFGARG-YGHI 173
              .:||:..:||.|..:| |.|:
plant   187 --ILYCKHHFAQLFKEKGSYNHL 207

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Mlp60A	NP_001137750.1	LIM1_MLP84B_like	10..63	CDD:188788	23/52 (44%)
		LIM_CRP_like	108..161	CDD:188712	18/88 (20%)
		LIM_CRP_like	213..266	CDD:188712
		LIM	316..369	CDD:413332
		LIM_CRP_like	412..465	CDD:188712
WLIM2b	NP_001190099.1	LIM1_SF3	6..68	CDD:188824	23/58 (40%)
WLIM2b	NP_001190099.1	LIM	108..202	CDD:295319	21/96 (22%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E2759_KOG1700
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	1	1.000	-	-		mtm966
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	1	1.000	-	-		X318
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	4	3.810