DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Mlp60A and crip2

DIOPT Version :9

Sequence 1:	NP_001137750.1	Gene:	Mlp60A / 37853	FlyBaseID:	FBgn0259209	Length:	486	Species:	Drosophila melanogaster
Sequence 2:	XP_012824147.1	Gene:	crip2 / 780192	XenbaseID:	XB-GENE-953187	Length:	220	Species:	Xenopus tropicalis

Alignment Length:	294	Identity:	82/294 - (27%)
Similarity:	111/294 - (37%)	Gaps:	91/294 - (30%)

- Green bases have known domain annotations that are detailed below.

  Fly    10 KCPACGKSVYAAEERVAGGYKFHKTCFKCSMCNKALDSTNCTEHEKELFC-KNCHGRKYGPKGYG 73
            |||.|.|:||.||:..:.|..:||.|.||..|||.|:.....||:.:.:| |.|:...|||||..
Frog     4 KCPKCDKTVYFAEKVTSLGKDWHKFCLKCERCNKTLNPGGHAEHDGKPYCHKPCYAALYGPKGVN 68

  Fly    74 FGGGAGCLSTDTGAHLNREFVPPKIPPKAPDGLGCPRCGIYVYAAEQMLARGKGYHRRCFKCVQC 138
            . ||||....|.....::...|.::.||                :::....|....|...|
Frog    69 I-GGAGSYIYDRKPSEDKPTSPTEVQPK----------------SDERKVSGPAPIRSLSK---- 112

  Fly   139 NKTLDSTLHCDGPDKDIYCRGCYAQKFGARGYGHIGISSLGLMSDIRDSEWQSDMAPKASIINVE 203
                                       ||:|                        :|.|. |...
Frog   113 ---------------------------GAQG------------------------SPPAD-ITAS 125

  Fly   204 QIQAPIGEG--CPRCGGVVFAAEQVLSKGRSWHRKCFKCRDCTKTLDSIIACDGP------DNEV 260
            .|....||.  ||||...|:.||:|.|.|:.|||.|.:|..|:|||.       |      |.:.
Frog   126 SITTFTGEPNLCPRCAQKVYFAEKVTSLGKDWHRPCLRCERCSKTLT-------PGSHAEHDGQP 183

  Fly   261 YC-KTCYGKKWGPHGYGF-ACGSSFLQTDGITEE 292
            || |.|||..:||.|... ..||...:.:.:.:|
Frog   184 YCHKPCYGILFGPKGVNTGGVGSYIYEKEPVNKE 217

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Mlp60A	NP_001137750.1	LIM1_MLP84B_like	10..63	CDD:188788	23/53 (43%)
		LIM_CRP_like	108..161	CDD:188712	3/52 (6%)
		LIM_CRP_like	213..266	CDD:188712	24/59 (41%)
		LIM	316..369	CDD:413332
		LIM_CRP_like	412..465	CDD:188712
crip2	XP_012824147.1	LIM1_TLP	5..58	CDD:188860	22/52 (42%)
crip2	XP_012824147.1	LIM1_TLP	137..190	CDD:188860	24/59 (41%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D1214165at2759
OrthoFinder	1	1.000	-	-		FOG0000284
OrthoInspector	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X318
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	3	3.010