DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Mlp60A and lima1

DIOPT Version :9

Sequence 1:	NP_001137750.1	Gene:	Mlp60A / 37853	FlyBaseID:	FBgn0259209	Length:	486	Species:	Drosophila melanogaster
Sequence 2:	NP_001072345.1	Gene:	lima1 / 779798	XenbaseID:	XB-GENE-987339	Length:	715	Species:	Xenopus tropicalis

Alignment Length:	220	Identity:	54/220 - (24%)
Similarity:	87/220 - (39%)	Gaps:	41/220 - (18%)

- Green bases have known domain annotations that are detailed below.

  Fly   183 DIRDSEWQSDMAPKASIIN---------VEQIQAPIGEGCPRCGGVVFAAEQVLSKGRSWHRKCF 238
            :|:.|....|.:|::.::|         |::.|.|..|.|..|...|:..|::.:..:.:|..||
Frog   315 EIQRSSSSPDYSPQSRVLNTMEPSPPKSVKKFQLPAREVCFSCQKTVYPMERLFANNQVYHNGCF 379

  Fly   239 KCRDC-TK-TLDSIIACDGPDNEVYCKTCYG---KKWGPHGYGFA------CGSSFLQTDGITEE 292
            :|..| || :|.:..:..|   .||||..:.   |..|.:..||.      ...:..:|.. |||
Frog   380 RCSHCSTKLSLGTFASLHG---TVYCKPHFNQLFKSKGNYDEGFGHKPHKELWVNKTETSE-TEE 440

  Fly   293 NLASERPFVAPDTTSIMAPDGEGCPRCGGAVFAAELQL------SKGKMYHRKCFNCARCTRPLD 351
            :.......::.|.:|   |..|..|.....|.||.::.      .|.|....|....| ...|.:
Frog   441 SPEQTTAHISKDPSS---PVVEEAPIAKVGVLAASMEAKNSSAQDKEKQVETKRLKIA-WPPPAE 501

  Fly   352 SVLACDGPDDNIYCKLCYAKLFGPK 376
            |..|....::||       |:..||
Frog   502 SSGAGGSGEENI-------KVLRPK 519

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Mlp60A	NP_001137750.1	LIM1_MLP84B_like	10..63	CDD:188788
		LIM_CRP_like	108..161	CDD:188712
		LIM_CRP_like	213..266	CDD:188712	17/54 (31%)
		LIM	316..369	CDD:413332	13/58 (22%)
		LIM_CRP_like	412..465	CDD:188712
lima1	NP_001072345.1	LIM_Eplin_alpha_beta	354..406	CDD:188869	17/54 (31%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.910