DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Mlp60A and Crip2

DIOPT Version :9

Sequence 1:	NP_001137750.1	Gene:	Mlp60A / 37853	FlyBaseID:	FBgn0259209	Length:	486	Species:	Drosophila melanogaster
Sequence 2:	NP_077185.1	Gene:	Crip2 / 68337	MGIID:	1915587	Length:	208	Species:	Mus musculus

Alignment Length:	213	Identity:	73/213 - (34%)
Similarity:	101/213 - (47%)	Gaps:	35/213 - (16%)

- Green bases have known domain annotations that are detailed below.

  Fly    10 KCPACGKSVYAAEERVAGGYKFHKTCFKCSMCNKALDSTNCTEHEKELFC-KNCHGRKYGPKGYG 73
            |||.|.|:||.||:..:.|..:||.|.||..|||.|......||:.:.|| |.|:...:||||..
Mouse     4 KCPKCDKTVYFAEKVSSLGKDWHKFCLKCERCNKTLTPGGHAEHDGKPFCHKPCYATLFGPKGVN 68

  Fly    74 FGGGAGCL----STD----TG--------AHLNREFVPPKIPPKA---------PDGLGCPRCGI 113
            .||....:    .|:    ||        ....:...|||.|.||         |:  .||||..
Mouse    69 IGGAGSYIYEKPQTEAPQVTGPIEVPVVRTEERKTSGPPKGPSKASSVTTFTGEPN--MCPRCNK 131

  Fly   114 YVYAAEQMLARGKGYHRRCFKCVQCNKTLDSTLHCDGPDKDIYC-RGCYAQKFGARGYGHIGISS 177
            .||.||::.:.||.:||.|.:|.:|:|||....|.: .|...|| :.||...||.:|   :...:
Mouse   132 RVYFAEKVTSLGKDWHRPCLRCERCSKTLTPGGHAE-HDGQPYCHKPCYGILFGPKG---VNTGA 192

  Fly   178 LGLMSDIRDSEWQSDMAP 195
            :|  |.|.|.:.:..:.|
Mouse   193 VG--SYIYDKDPEGTVQP 208

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Mlp60A	NP_001137750.1	LIM1_MLP84B_like	10..63	CDD:188788	24/53 (45%)
		LIM_CRP_like	108..161	CDD:188712	22/53 (42%)
		LIM_CRP_like	213..266	CDD:188712
		LIM	316..369	CDD:413332
		LIM_CRP_like	412..465	CDD:188712
Crip2	NP_077185.1	LIM1_TLP	5..58	CDD:188860	23/52 (44%)
Crip2	NP_077185.1	LIM1_TLP	126..179	CDD:188860	22/53 (42%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E2759_KOG1700
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D1214165at2759
OrthoFinder	1	1.000	-	-		FOG0000284
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X318
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	5	4.820