DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Mlp60A and crip3

DIOPT Version :9

Sequence 1:	NP_001137750.1	Gene:	Mlp60A / 37853	FlyBaseID:	FBgn0259209	Length:	486	Species:	Drosophila melanogaster
Sequence 2:	XP_021323078.1	Gene:	crip3 / 556515	ZFINID:	ZDB-GENE-130530-620	Length:	213	Species:	Danio rerio

Alignment Length:	209	Identity:	73/209 - (34%)
Similarity:	93/209 - (44%)	Gaps:	42/209 - (20%)

- Green bases have known domain annotations that are detailed below.

  Fly   213 CPRCGGVVFAAEQVLSKGRSWHRKCFKCRDCTKTLDSIIACDG---PDNEVYC-KTCYGKKWGPH 273
            ||||...||.||:|.|.|::|||.|.||..|:|    |::..|   .|...|| |.|||..:||.
Zfish     5 CPRCDKTVFFAEKVSSLGKNWHRFCLKCERCSK----ILSPGGHAEHDGLPYCHKPCYGTLFGPK 65

  Fly   274 GYGFACGSSFL-----QTDGITEENLASERPFVAPDTTS---------------IMAPDGEGCPR 318
            |.......|::     ||......|..||.....|.|||               :.|.:...||.
Zfish    66 GVNIGGAGSYIYDTPPQTPVNKTCNSPSEGSPTTPWTTSQINFNQPKAATAPARMFAGETYLCPG 130

  Fly   319 CGGAVFAAELQLSKGKMYHRKCFNCARCTRPLDSVLACDGP------DDNIYCKL-CYAKLFGPK 376
            ||.||:.||..:|.|:.:||.|..|.||.:.|.       |      :.:.||.: ||..|||||
Zfish   131 CGKAVYFAEKVMSLGRNWHRPCLRCVRCKKTLT-------PGGHAEHEGSPYCHVPCYGYLFGPK 188

  Fly   377 GVGYGHTPTLVSTN 390
            ||..|.....:..|
Zfish   189 GVNIGRVGCYIYEN 202

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Mlp60A	NP_001137750.1	LIM1_MLP84B_like	10..63	CDD:188788
		LIM_CRP_like	108..161	CDD:188712
		LIM_CRP_like	213..266	CDD:188712	25/56 (45%)
		LIM	316..369	CDD:413332	20/59 (34%)
		LIM_CRP_like	412..465	CDD:188712
crip3	XP_021323078.1	LIM1_TLP	5..58	CDD:188860	25/56 (45%)
crip3	XP_021323078.1	LIM2_TLP	128..181	CDD:188861	20/59 (34%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E2759_KOG1700
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D1214165at2759
OrthoFinder	1	1.000	-	-		FOG0000284
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	4	3.820