DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Mlp60A and csrp2

DIOPT Version :9

Sequence 1:	NP_001137750.1	Gene:	Mlp60A / 37853	FlyBaseID:	FBgn0259209	Length:	486	Species:	Drosophila melanogaster
Sequence 2:	XP_012814488.1	Gene:	csrp2 / 549369	XenbaseID:	XB-GENE-943913	Length:	196	Species:	Xenopus tropicalis

Alignment Length:	174	Identity:	77/174 - (44%)
Similarity:	106/174 - (60%)	Gaps:	12/174 - (6%)

- Green bases have known domain annotations that are detailed below.

  Fly    10 KCPACGKSVYAAEERVAGGYKFHKTCFKCSMCNKALDSTNCTEHEKELFCKNCHGRKYGPKGYGF 74
            ||.|||.:||.|||....|..:||.||.|.:|.|.||||....|:.|::|::|:|:||||||||:
Frog    13 KCGACGSNVYHAEEVQCDGKSYHKCCFLCMVCRKNLDSTTVAIHDNEIYCRSCYGKKYGPKGYGY 77

  Fly    75 GGGAGCLSTDTGAHL-----------NREFVPPKIPPKAPDGLGCPRCGIYVYAAEQMLARGKGY 128
            |.|||.|:.|.|..|           |....|.|...|......||||...|||||:::..||.:
Frog    78 GQGAGTLNMDRGERLGIKPEENLARQNTSSNPSKFAQKFGGAEKCPRCNESVYAAEKIMGAGKPW 142

  Fly   129 HRRCFKCVQCNKTLDSTLHCDGPDKDIYCRGCYAQKFGARGYGH 172
            |:.||:|.:|.|:|:||...: .:.:|||:.|||:.||.:|:|:
Frog   143 HKNCFRCAKCGKSLESTTLTE-KEGEIYCKACYAKNFGPKGFGY 185

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Mlp60A	NP_001137750.1	LIM1_MLP84B_like	10..63	CDD:188788	25/52 (48%)
		LIM_CRP_like	108..161	CDD:188712	23/52 (44%)
		LIM_CRP_like	213..266	CDD:188712
		LIM	316..369	CDD:413332
		LIM_CRP_like	412..465	CDD:188712
csrp2	XP_012814488.1	LIM1_CRP2	13..67	CDD:188864	26/53 (49%)
csrp2	XP_012814488.1	LIM2_CRP2	122..175	CDD:188871	24/53 (45%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	1	1.000	82	1.000	Domainoid score	I8277
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D1214165at2759
OrthoFinder	1	1.000	-	-		FOG0000284
OrthoInspector	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X318
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	4	4.010