DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Mlp60A and crip3

DIOPT Version :9

Sequence 1:	NP_001137750.1	Gene:	Mlp60A / 37853	FlyBaseID:	FBgn0259209	Length:	486	Species:	Drosophila melanogaster
Sequence 2:	NP_001015811.1	Gene:	crip3 / 548528	XenbaseID:	XB-GENE-5943480	Length:	203	Species:	Xenopus tropicalis

Alignment Length:	195	Identity:	66/195 - (33%)
Similarity:	96/195 - (49%)	Gaps:	28/195 - (14%)

- Green bases have known domain annotations that are detailed below.

  Fly     8 TPKCPACGKSVYAAEERVAGGYKFHKTCFKCSMCNKALDSTNCTEHEKELFC-KNCHGRKYGPKG 71
            |.:||.|...||.||:..:.|..:|:.|.||.:|||.|.:....||:.:.:| |.|:|..:||||
Frog     2 TSQCPRCRAPVYFAEKVSSLGKNWHRFCLKCELCNKILSAGGHAEHDGQPYCHKPCYGALFGPKG 66

  Fly    72 YGFGGGAGCLSTDTGAHLNREFVPP-------------KIPPKAPDGLG--------CPRCGIYV 115
            ... ||.|....||...:::..|.|             |...|||..:.        ||.||..|
Frog    67 VNI-GGVGSYIYDTTPQISQNPVSPTLCVPNHSSSTNTKPATKAPAPMRTFAGETALCPGCGKPV 130

  Fly   116 YAAEQMLARGKGYHRRCFKCVQCNKTLDSTLHCDGPDKDIYCR-GCYAQKFGARGYGHIGISSLG 179
            :.||::::.|:.:||.|.:|.:|||||.:..|.: .|...||. .||...||.:|   :.|..:|
Frog   131 FFAEKVMSLGRNWHRPCLRCQRCNKTLTAGGHAE-HDGLPYCHVPCYGYLFGPKG---VNIGDVG 191

Fly 180 179
Frog 192 191

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Mlp60A	NP_001137750.1	LIM1_MLP84B_like	10..63	CDD:188788	20/53 (38%)
		LIM_CRP_like	108..161	CDD:188712	21/53 (40%)
		LIM_CRP_like	213..266	CDD:188712
		LIM	316..369	CDD:413332
		LIM_CRP_like	412..465	CDD:188712
crip3	NP_001015811.1	LIM1_TLP	5..58	CDD:188860	20/52 (38%)
crip3	NP_001015811.1	LIM2_TLP	123..176	CDD:188861	21/53 (40%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D1214165at2759
OrthoFinder	1	1.000	-	-		FOG0000284
OrthoInspector	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	2.010