DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Mlp60A and csrp3

DIOPT Version :9

Sequence 1:	NP_001137750.1	Gene:	Mlp60A / 37853	FlyBaseID:	FBgn0259209	Length:	486	Species:	Drosophila melanogaster
Sequence 2:	NP_001307020.1	Gene:	csrp3 / 450005	ZFINID:	ZDB-GENE-041010-119	Length:	222	Species:	Danio rerio

Alignment Length:	177	Identity:	84/177 - (47%)
Similarity:	106/177 - (59%)	Gaps:	18/177 - (10%)

- Green bases have known domain annotations that are detailed below.

  Fly    10 KCPACGKSVYAAEERVAGGYKFHKTCFKCSMCNKALDSTNCTEHEKELFCKNCHGRKYGPKGYGF 74
            ||.||.|:||.|||.......||||||.|.:|.|.||||....||.|::||.|:|:||||||||:
Zfish    38 KCAACEKTVYHAEEIQCNSRSFHKTCFICMVCRKGLDSTTVAAHESEIYCKTCYGKKYGPKGYGY 102

  Fly    75 GGGAGCLSTDTGAHLNREFVP--PKIPPKAPDGLG-------------CPRCGIYVYAAEQMLAR 124
            |.|||.||:|...  |.|..|  ||.|..||....             ||||...|||||:::..
Zfish   103 GQGAGALSSDPVN--NEELQPQEPKAPRPAPANSNSSKFAQKFGSTDRCPRCSKAVYAAEKIMGA 165

  Fly   125 GKGYHRRCFKCVQCNKTLDSTLHCDGPDKDIYCRGCYAQKFGARGYG 171
            ||.:|:.||:|:.|.|:|:||...| .|.::||:.|||:.||.:|.|
Zfish   166 GKPWHKTCFRCLLCGKSLESTTVTD-KDGELYCKVCYAKNFGPKGRG 211

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Mlp60A	NP_001137750.1	LIM1_MLP84B_like	10..63	CDD:188788	28/52 (54%)
		LIM_CRP_like	108..161	CDD:188712	24/52 (46%)
		LIM_CRP_like	213..266	CDD:188712
		LIM	316..369	CDD:413332
		LIM_CRP_like	412..465	CDD:188712
csrp3	NP_001307020.1	LIM1_CRP3	38..91	CDD:188865	28/52 (54%)
csrp3	NP_001307020.1	LIM2_CRP3	149..202	CDD:188866	25/53 (47%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C170575194
Domainoid	1	1.000	79	1.000	Domainoid score	I8580
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	1	1.000	-	-		H20742
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D1214165at2759
OrthoFinder	1	1.000	-	-		FOG0000284
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R4662
SonicParanoid	1	1.000	-	-		X318
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	8	7.880