DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Mlp60A and Mical

DIOPT Version :9

Sequence 1:	NP_001137750.1	Gene:	Mlp60A / 37853	FlyBaseID:	FBgn0259209	Length:	486	Species:	Drosophila melanogaster
Sequence 2:	NP_001247015.1	Gene:	Mical / 41225	FlyBaseID:	FBgn0053208	Length:	4743	Species:	Drosophila melanogaster

Alignment Length:	249	Identity:	60/249 - (24%)
Similarity:	83/249 - (33%)	Gaps:	83/249 - (33%)

- Green bases have known domain annotations that are detailed below.

  Fly    45 LDST--NCTEHEK--ELFCKNCHGRKYGPKGYGFGGGAGCLSTDTGAHLNREFVPPKIPPKAPDG 105
            :||.  |..|.||  ||..|.   ..:||||                   ||.||.
  Fly   953 IDSNDWNVREIEKKIELSKKT---EIHGPKG-------------------REKVPK--------- 986

  Fly   106 LGCPRCGIYVYAAEQMLARGKGYHRRC------------FKCV-QCNKTLDSTLHCDGPDKDIYC 157
                      ::.||..||   .|:..            ||.: |..:.||..|. :|.:.|:..
  Fly   987 ----------WSKEQFQAR---QHKMSKPQRQDSREAEKFKDIDQTIRNLDKQLK-EGHNLDVGE 1037

  Fly   158 RG-----CYAQKFGARGYGHIGISSLGLMSDIRDSEWQSDMAPKAS--IINVEQIQAPIGEGCPR 215
            ||     ..|.:||.:...:....:.|  |....:...:.:.||:|  :....:.|| ..|.|..
  Fly  1038 RGRNKVASIAGQFGKKDEANSDEKNAG--SSNATTNTNNTVIPKSSSKVALAFKKQA-ASEKCRF 1099

  Fly   216 CGGVVFAAEQVLSKGRSWHRKCFKCRDCTKTL-------DSIIACDGPDNEVYC 262
            |...|:..|:...:|...||.|.||..|...|       |.    |.|....||
  Fly  1100 CKQTVYLMEKTTVEGLVLHRNCLKCHHCHTNLRLGGYAFDR----DDPQGRFYC 1149

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Mlp60A	NP_001137750.1	LIM1_MLP84B_like	10..63	CDD:188788	9/21 (43%)
		LIM_CRP_like	108..161	CDD:188712	15/70 (21%)
		LIM_CRP_like	213..266	CDD:188712	17/57 (30%)
		LIM	316..369	CDD:413332
		LIM_CRP_like	412..465	CDD:188712
Mical	NP_001247015.1	MDR	<114..>160	CDD:302572
		CH	563..>629	CDD:294029
		LIM_Mical	1097..1153	CDD:188823	17/57 (30%)
		Ehrlichia_rpt	<2081..2479	CDD:118064
		DUF3585	4592..4705	CDD:288945
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E2759_KOG1700
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	1	1.000	-	-		otm2983
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	3	2.810