DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment Mlp60A and csrp1a

DIOPT Version :9

Sequence 1:	NP_001137750.1	Gene:	Mlp60A / 37853	FlyBaseID:	FBgn0259209	Length:	486	Species:	Drosophila melanogaster
Sequence 2:	NP_991130.1	Gene:	csrp1a / 378726	ZFINID:	ZDB-GENE-030909-4	Length:	192	Species:	Danio rerio

Alignment Length:	175	Identity:	82/175 - (46%)
Similarity:	104/175 - (59%)	Gaps:	13/175 - (7%)

- Green bases have known domain annotations that are detailed below.

  Fly    10 KCPACGKSVYAAEERVAGGYKFHKTCFKCSMCNKALDSTNCTEHEKELFCKNCHGRKYGPKGYGF 74
            ||..|.|:||.|||....|..||::||.|.:|.|.||||....||.|::||.|:|:||||||||:
Zfish     8 KCGCCQKTVYFAEEVQCEGRSFHRSCFLCMVCRKNLDSTTVAVHENEIYCKACYGKKYGPKGYGY 72

  Fly    75 GGGAGCLSTDTGAHLNREFVPP------------KIPPKAPDGLGCPRCGIYVYAAEQMLARGKG 127
            |.|||.||.|.|..|..:.|.|            |...|......||||...|||||:::..|..
Zfish    73 GAGAGTLSMDKGESLGIKVVEPQNHQPTNNPNTSKFAQKFGGSDVCPRCSKAVYAAEKVIGAGNA 137

  Fly   128 YHRRCFKCVQCNKTLDSTLHCDGPDKDIYCRGCYAQKFGARGYGH 172
            :||.||:|..|.|.|:||...| .|.:|||:||||:.||.:|:|:
Zfish   138 WHRGCFRCAMCGKGLESTTLAD-KDGEIYCKGCYAKNFGPKGFGY 181

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Mlp60A	NP_001137750.1	LIM1_MLP84B_like	10..63	CDD:188788	26/52 (50%)
		LIM_CRP_like	108..161	CDD:188712	26/52 (50%)
		LIM_CRP_like	213..266	CDD:188712
		LIM	316..369	CDD:413332
		LIM_CRP_like	412..465	CDD:188712
csrp1a	NP_991130.1	LIM1_CRP1	7..62	CDD:188863	27/53 (51%)
csrp1a	NP_991130.1	LIM2_CRP	118..171	CDD:188787	27/53 (51%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C170575191
Domainoid	1	1.000	79	1.000	Domainoid score	I8580
eggNOG	1	0.900	-	-		E2759_KOG1700
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D1214165at2759
OrthoFinder	1	1.000	-	-		FOG0000284
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R4662
SonicParanoid	1	1.000	-	-		X318
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	8	7.780